Antidiarrhoeal Activity of Abutilon indicum Linn Leaf Extract

Objective: The present study is aimed to evaluate the leaf extracts of Abutilon indicum for acclaimed anti-diarrhoeal activity using albino rats. Materials and methods: Anti-diarrhoeal activity of Abutilon indicum was evaluated by gastro intestinal motility, castor oil-induced diarrhoea and prostaglandin E₂ -induced enteropooling in rats. Loperamide was used as a standard drug. Results : The study revealed that, the methanolic extract and aqueous extract possessed significant antidiarrhoeal activity in castor oil-induced diarrhoea and prostaglandin E₂-induced diarrhoea, compared to the control group. Conclusion: Abutilon indicum showed significant anti-diarrhoeal activity as compared to loperamide and can be recommended for further studies.