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Antimicrobial, Antioxidant and Anticancer Activity of the Ethanol Extract of Pleurotus ostreatus


Affiliations
1 Molecular Diagnostics & Biomolecule Characterization Lab, Department of Biotechnology, Bannari Amman Institute of Technology, Sathyamangalam – 638401, Erode District, Tamil Nadu, India
 

The current study evaluates antimicrobial, antioxidant and anticancer activity of the ethanol extract of Pleurotus ostreatus. Chemical analysis showed the presence of alcohol, amides, alkanes, ether, phenol and sulphides. Most of the chemical constituents were found to be esters and carboxylic acid derivatives. The extract showed highest resistant against Bacillus cereus. P. ostreatus ethanol extract showed comparable antioxidant activity with ascorbic acid in both DPPH and FRAP method and also showed an IC50 of 39.29 μg/ml against HL60 cells.

Keywords

MTT, DPPH, HL-60 Cells, FRAP, GC-MS.
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  • Antimicrobial, Antioxidant and Anticancer Activity of the Ethanol Extract of Pleurotus ostreatus

Abstract Views: 277  |  PDF Views: 240

Authors

J. Bindhu
Molecular Diagnostics & Biomolecule Characterization Lab, Department of Biotechnology, Bannari Amman Institute of Technology, Sathyamangalam – 638401, Erode District, Tamil Nadu, India
Arunava Das
Molecular Diagnostics & Biomolecule Characterization Lab, Department of Biotechnology, Bannari Amman Institute of Technology, Sathyamangalam – 638401, Erode District, Tamil Nadu, India
E. Vihashinee
Molecular Diagnostics & Biomolecule Characterization Lab, Department of Biotechnology, Bannari Amman Institute of Technology, Sathyamangalam – 638401, Erode District, Tamil Nadu, India
A. Rubiga
Molecular Diagnostics & Biomolecule Characterization Lab, Department of Biotechnology, Bannari Amman Institute of Technology, Sathyamangalam – 638401, Erode District, Tamil Nadu, India
Aswin Edward
Molecular Diagnostics & Biomolecule Characterization Lab, Department of Biotechnology, Bannari Amman Institute of Technology, Sathyamangalam – 638401, Erode District, Tamil Nadu, India
R. Eswaran
Molecular Diagnostics & Biomolecule Characterization Lab, Department of Biotechnology, Bannari Amman Institute of Technology, Sathyamangalam – 638401, Erode District, Tamil Nadu, India
G. Shanmuga Priya
Molecular Diagnostics & Biomolecule Characterization Lab, Department of Biotechnology, Bannari Amman Institute of Technology, Sathyamangalam – 638401, Erode District, Tamil Nadu, India
S. Soundariya
Molecular Diagnostics & Biomolecule Characterization Lab, Department of Biotechnology, Bannari Amman Institute of Technology, Sathyamangalam – 638401, Erode District, Tamil Nadu, India
Aileen Rose Edwin
Molecular Diagnostics & Biomolecule Characterization Lab, Department of Biotechnology, Bannari Amman Institute of Technology, Sathyamangalam – 638401, Erode District, Tamil Nadu, India

Abstract


The current study evaluates antimicrobial, antioxidant and anticancer activity of the ethanol extract of Pleurotus ostreatus. Chemical analysis showed the presence of alcohol, amides, alkanes, ether, phenol and sulphides. Most of the chemical constituents were found to be esters and carboxylic acid derivatives. The extract showed highest resistant against Bacillus cereus. P. ostreatus ethanol extract showed comparable antioxidant activity with ascorbic acid in both DPPH and FRAP method and also showed an IC50 of 39.29 μg/ml against HL60 cells.

Keywords


MTT, DPPH, HL-60 Cells, FRAP, GC-MS.

References





DOI: https://doi.org/10.18311/jnr%2F2020%2F24382