El-Sharkawy Eman Ramdan ¹, zEd-Dra Abdelazi ², Emad Mohamed Abdallah ³

Affiliations
1 Department of Eco-Physiology, Desert Research Center, 15753, Cairo, EG
2 Laboratory of Chemistry-Biology Applied to the Environment, Department of Biology, Moulay Ismail University, Meknes, MA
3 Department of Laboratory Sciences, College of Sciences and Arts, Qassim University, Al-Rass, SA

Abstract

Plant extracts could be beneficial for biocontrol of macro-organisms and micro-organisms which attack plants and it could be also beneficial for protection or treatment of some diseases in animals and human. In the current study, two plants from the arid areas in the Northern Regions in Saudi Arabia, namely, Farsetia hamiltonii and Launaea nudicaulis were screened for their phytochemical, antimicrobial and antioxidant properties. GC-MS screening of methanol extract of flowers of F. hamiltonii revealed the presence of triterpen compound (Betulins, Lanosterin), and quercterin. The methanol extract of L. nudicaulis revealed the presence of dihydro-isosteviolmethylester and flavone-4’-OH,5-OH,7-di-O-glucoside. Dihydrotorulosol and Urs-12-ene-3-one were detected in two extracts, where chloroform extract of Launaea were rich in alkaloid compounds, aspidofractinin, and tocopherol. The antioxidant activity showed that the chloroform extract of L. nudicaulis had higher antioxidant activity (IC50=1.6±0.1g/L; EC50=2.15±0.3g/L), followed by methanol extract of F. hamiltonii (IC50=3.6±0.1g/L; EC50=4.1±0.1g/L) and methanol extract of L. nudicaulis (IC50=7.1±0.2g/L;EC50=7.85±0.4g/L). The microbiological investigation revealed that methanol extract of F. hamitonii and chloroform extract of Launaea nudicaulis showed no antimicrobial activity against all tested microorganisms. While the methanol extract of L. nudica exhibited average antibacterial activity against Staphylococcus epidermidis ATCC 12228 and weak antibacterial activity against S. aureus ATCC 25923 and Escherichia coli ATCC 35218.

Keywords

Antimicrobial, Antioxidant, Farsetia hamiltonii, Launaea nudicaulis, Phytochemical Components.

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