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Authors
Affiliations
1 Department of Physiology, SRDC Faridabad(HR), IN
2 Department of Physiology, IN
3 Physiology, IN
4 Department of Surgery, Oncology Unit, HIMS, Jolly Grant, Dehradun, IN
Source
International Journal of Physiology, Vol 2, No 1 (2014), Pagination: 44-49
Abstract
Background: Muscle hypothesis implicates abnormalities in peripheral muscle as a source of stimulus for symptoms and reflex abnormalities seen in chronic heart failure.
Aim: To evaluate ergoreflex contribution to CRRto isometric exercise in CP.
Material and Results: We studied 30 CP (age- 56.1±0.7) and 30 age matched normal subjects (age- 55.0±0.7). Post exercise regional circulatory occlusion method (PE-RCO) was used to assess ergoreflex. We compared cardiaorespiratory responses to sustained handgrip and during a 3-minute period of post exercise regional circulatory occlusion (PE-RCO). Contributions made specifically by ergoreflex to cardiorespiratory parameters in responses to exercise were derived by calculating absolute difference in these parameters during 10min recovery between with PE-RCO and without PE-RCO. CP showed significant ergoreflex activation compared with control subjects in term of Heart Rate and Respiratory Rate.
Conclusion: Ergoreflex is overactive in CP.
Keywords
Cancer, Cachexia, Ergoreceptors, Ergoreflex, CCR:Cardiorespiratory Responses, CP: Cancer Patients
