International Journal of Physiology

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Contribution of Ergoreflex to Crrto Isometric Exercise in CP


Affiliations
1 Department of Physiology, SRDC Faridabad(HR), India
2 Department of Physiology, India
3 Physiology, India
4 Department of Surgery, Oncology Unit, HIMS, Jolly Grant, Dehradun, India
     

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Background: Muscle hypothesis implicates abnormalities in peripheral muscle as a source of stimulus for symptoms and reflex abnormalities seen in chronic heart failure.

Aim: To evaluate ergoreflex contribution to CRRto isometric exercise in CP.

Material and Results: We studied 30 CP (age- 56.1±0.7) and 30 age matched normal subjects (age- 55.0±0.7). Post exercise regional circulatory occlusion method (PE-RCO) was used to assess ergoreflex. We compared cardiaorespiratory responses to sustained handgrip and during a 3-minute period of post exercise regional circulatory occlusion (PE-RCO). Contributions made specifically by ergoreflex to cardiorespiratory parameters in responses to exercise were derived by calculating absolute difference in these parameters during 10min recovery between with PE-RCO and without PE-RCO. CP showed significant ergoreflex activation compared with control subjects in term of Heart Rate and Respiratory Rate.

Conclusion: Ergoreflex is overactive in CP.


Keywords

Cancer, Cachexia, Ergoreceptors, Ergoreflex, CCR:Cardiorespiratory Responses, CP: Cancer Patients
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  • Contribution of Ergoreflex to Crrto Isometric Exercise in CP

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Authors

Manveen Kaur
Department of Physiology, SRDC Faridabad(HR), India
Rani Gupta
Department of Physiology, India
Abha Shrivastava
Physiology, India
Sunil Saini
Department of Surgery, Oncology Unit, HIMS, Jolly Grant, Dehradun, India

Abstract


Background: Muscle hypothesis implicates abnormalities in peripheral muscle as a source of stimulus for symptoms and reflex abnormalities seen in chronic heart failure.

Aim: To evaluate ergoreflex contribution to CRRto isometric exercise in CP.

Material and Results: We studied 30 CP (age- 56.1±0.7) and 30 age matched normal subjects (age- 55.0±0.7). Post exercise regional circulatory occlusion method (PE-RCO) was used to assess ergoreflex. We compared cardiaorespiratory responses to sustained handgrip and during a 3-minute period of post exercise regional circulatory occlusion (PE-RCO). Contributions made specifically by ergoreflex to cardiorespiratory parameters in responses to exercise were derived by calculating absolute difference in these parameters during 10min recovery between with PE-RCO and without PE-RCO. CP showed significant ergoreflex activation compared with control subjects in term of Heart Rate and Respiratory Rate.

Conclusion: Ergoreflex is overactive in CP.


Keywords


Cancer, Cachexia, Ergoreceptors, Ergoreflex, CCR:Cardiorespiratory Responses, CP: Cancer Patients