International Journal of Physiology

Open Access Open Access  Restricted Access Subscription Access
Open Access Open Access Open Access  Restricted Access Restricted Access Subscription Access

A Comparitive Study:Autonomic Functions in Cerebral Palsy Individuals and Their Siblings


Affiliations
1 Department of Physiology, Bowring and lady Curzon medical college and research Institute, Bangalore, Karnataka, India
2 Department of Physiology, Vijayanagar Institute of Medical Sciences, Ballari, Karnataka, India
     

   Subscribe/Renew Journal


Introduction: It is defined as an “umbrella term covering a group of non-progressive, but often changing, motor impairment syndromes secondary to lesions or anomalies of the brain arising in the early stages of its development”1 primarily leading to a disorder of movement and posture. Objective: To assess autonomic functions in cerebral palsy individuals and their siblings. Method: Twenty cerebral palsy and sibling volunteers with no neurological damage were recruited for the study. Heart rate variability was used to assess the autonomic function. HRV was recorded in supine position for 5 minutes under quiet, calm conditions. Time domain parameters and frequency domain parameters were analyzed. Results: There was no statistically significant difference in any of the HRV parameters. There was no significant difference in HRV parameters in children with CP and healthy children indicating a normal sympatho-vagal balance. Conclusion: The presence of normal sympatho vagal balance in CP predicts that patients with CP have the same predilection as the general population to abnormalities associated with sympatho-vagal balance.

Keywords

Cerebral Palsy, HRV, Sympathetic Activity, Parasympathetic Activity, Sympatho Vagal Balance.
Subscription Login to verify subscription
User
Notifications
Font Size


  • Mutch L, Alberman E, Hagberg B, Kodama K, Perat MV. Cerebral palsy epidemiology: where are we now and where are we going. Dev Med Child Neurol. 1992; 34:547-551.

  • 23 Martha Wilson Jones, Elaine Morgan, Jean E. Shelton, Christine Thorogood. Cerebral Palsy: Introduction and Diagnosis (Part 1). MD J Pediatr Health Care. 2007; 21(3):146-152.

  • Bass N. Cerebral palsy and neurodegenerative disease. Curr Opin Pediatric 1999; 11: 504-507.

  • United Cerebral Palsy (2005) Press room: cerebral palsy - facts & figures. Available from: URL http://www.ucerebral palsy.org/ucerebral palsy_generaldoc.cfm/1/9/37/37-37/447.

  • MacLennan A. A template for defining a causal relation between acute intrapartum events and cerebral palsy: international consensus statement. BMJ 1999; 319:1054-1059.

  • Heart rate variability. Standards of measurement, physiological interpretation, and clinical use. Task for of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology. Eur Heart J 1996; 17:354–81.

  • Jalife J, Michaels DC. Neural control of sinoatrial pacemaker activity. In: Levy MN, Schwartz PJ, eds. Vagal Control of the Heart: Experimental Basis and Clinical Implications. Armonk, NY: Futura; 1994:173-205.

  • Chess GF, Tam RMK, Calaresu FR. Influence of cardiac neural inputs on rhythmic variations of heart period in the cat. Am J Physiol.1975; 228:775-780.

  • Larson SK, Porges SW. The ontogeny of heart period patterning in the rat. Dev fsychobiol 1982; 15:519.


Abstract Views: 484

PDF Views: 0




  • A Comparitive Study:Autonomic Functions in Cerebral Palsy Individuals and Their Siblings

Abstract Views: 484  |  PDF Views: 0

Authors

P. Sowmya
Department of Physiology, Bowring and lady Curzon medical college and research Institute, Bangalore, Karnataka, India
J. Govindaraj
Department of Physiology, Vijayanagar Institute of Medical Sciences, Ballari, Karnataka, India

Abstract


Introduction: It is defined as an “umbrella term covering a group of non-progressive, but often changing, motor impairment syndromes secondary to lesions or anomalies of the brain arising in the early stages of its development”1 primarily leading to a disorder of movement and posture. Objective: To assess autonomic functions in cerebral palsy individuals and their siblings. Method: Twenty cerebral palsy and sibling volunteers with no neurological damage were recruited for the study. Heart rate variability was used to assess the autonomic function. HRV was recorded in supine position for 5 minutes under quiet, calm conditions. Time domain parameters and frequency domain parameters were analyzed. Results: There was no statistically significant difference in any of the HRV parameters. There was no significant difference in HRV parameters in children with CP and healthy children indicating a normal sympatho-vagal balance. Conclusion: The presence of normal sympatho vagal balance in CP predicts that patients with CP have the same predilection as the general population to abnormalities associated with sympatho-vagal balance.

Keywords


Cerebral Palsy, HRV, Sympathetic Activity, Parasympathetic Activity, Sympatho Vagal Balance.

References