Erosion and sediment transport are very important issues in river researches. Using of mathematical models are suitable tools for simulation of flow regime and sediment transport conditions in the rivers. Karkheh River Catchment is very important basin of Iran that located in south western of Iran. Karkheh River is third biggest river of Iran. Karkheh Reservoir Dam is one of the largest dam in Iran that is located in Khouzestan Province near Andimeshk City. In this research, we simulated flow regime and sediment transport in Karkheh River in downstream of Karkheh Reservoir Dam. Downstream of Karkheh River condition after construction of the Reservoir Dam is simulated and evaluated using the famous numerical model of MIKE 11. The study period of this research is exactly ten years, Between 2001 and 2010. The river reach is about 100 Km, between Abdolkhan Hydrometric Station and Hamidiyeh Hydrometric Station which their data were used for this investigation.The Manning coefficient of 0.025 estimated and selected to use on hydrodynamic model of MIKE 11 software and acceptable hydraulic and sediment results were obtained, the total sediment load transport methods of Engelund-Hansen and Ackers-White represent more desirable results for the different flow discharges. The results show that downstream of Karkheh River in Hamidiyeh Hydrometric Station has more sediment transport capacity.
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