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Rupali, Wagh
- Quantification of Itopride Hydrochloride from Tablet Dosage Form by Visible Spectroscopy
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Authors
A. Salunke Poonam
1,
Kadam Lalit
1,
Jaiswal Nikita
1,
Jain Roshan
1,
Patil Shital
1,
Wagh Rupali
1,
S. D. Barhate
1
Affiliations
1 Shree Sureshdada Jain Institute of Pharmaceutical Education and Research, Jamner, Dist-Jalgaon, IN
1 Shree Sureshdada Jain Institute of Pharmaceutical Education and Research, Jamner, Dist-Jalgaon, IN
Source
Research Journal of Pharmacy and Technology, Vol 11, No 1 (2018), Pagination: 121-125Abstract
The present study to describe the Quantification of Itopride Hydrochloride from tablet dosage form by visible spectroscopy by applying principle of colorimetric study. It involves the measurement of the amount of ultraviolet (190-380 nm) or visible (380-800nm) radiation absorbed by a substance in solution. The final optimised method carried out on double beam UV-visible spectrophotometer (Shimadzu, model 1800) having two matched quartz cells with 1 cm light path by using Bromothymol blue of concentration 0.5% w/v solution. Itopride Hydrochloride detection wavelength was set at 479.40nm The linearity was found to be in the range of 10-50μg/ml. This method for the quantitative determination of the drug by validation in accordance with the International Conference on Harmonization. The proposed method is economic, simple, sensitive, reproducible, and accurate and no interference is observed due to common excipients of tablet. The proposed method was successfully applied to determination of Itopride hydrochloride in pharmaceutical formulations.Keywords
Itopride Hydrochloride, UV-Visible Spectrophotometer, Analytical Method Validation, Acid-Dye Method.
References
- Hobart H. Willard, Lynne L. Merritt, Jr, John A. Dean, Frank A. Settle, Jr, Instrumental Method of Analysis, CBS Publication and Distributor, Delhi, 7(2), 118-158.
- A.H. Beckett and J.B. Stenlake, Practical Pharmaceutical Chemistry, CBS Publisher and Distributor, Delhi, 4(2), 275-277.
- A.H. Beckett and J.B. Stenlake, Practical Pharmaceutical Chemistry, CBS Publisher and Distributor, Delhi, 4(2), 275-277.
- A.H. Beckett and J.B. Stenlake, Practical Pharmaceutical Chemistry, 4th Edition Part Two, CBS Publisher and Distributor, Delhi, 4(2), 30.
- http://www.druginfosys.com/drug.aspx?drugcode=1599andtype=1. https://en.wikipedia.org/wiki/Itopride.
- Kd. Tripathi, Essential of Medical Pharmacology, 6th Edition, Jaypee Brohers, New Delhi, 627.
- Hussainy, Areefulla S, Smitha G, Swamy PV, Raju SA. Spectrophotometric Determination of Itopride Hydrochloride. Int. J Chem. Sci 2006; 4(3): 713-716.
- Singh SS, Jain M, Sharma K, Shah B, Vyas M, Thakpar P, Et Al. Quantitation of Itopride In Human Serum By High Performance Liquid Chromatography With Fluorescence Detection and Its Application To A Bioequivalence Study. J Charatogr B Analyst Technol Biomed Life Sci 2005; 818(2): 213-220.
- Kaul N, Agrawal H, Maske, PR, Ramchandra J, Mahadik, KR, Kadam, SS. Chromatographic Determination of Itopride Hydrochloride In The Presence of Its Degradation Products. J Separ Sci 2005; 28(13): 1566-1576.
- Suganthi A, Karthikeyan R, Ravi TK. HPTLC Methods for Estimation of Itopride Hydrochloride From Its Tablet Formulations. Indian Drugs 2006; 43(10): 827-830.
- Prof. Manohar A. Potdar, Pharmaceutical Quality Assurance, 3rd Edition, October 2013, Nirali Prakashan, 8.28.