Informatics Publishing Limited

L. Malathi ¹, K. M. K. Masthan ¹, Sudha Jimson ¹, V. Hemasri ¹

Affiliations
1 Dept of Oral Pathology Sree Balaji Dental College & Hospital, Bharath Institute of Higher Education and Research, IN

Abstract

Verrucous carcinoma is a variant of squamous cell carcinoma. It most typically affects the mouth with buccal mucous membrane being the most typical site affected. Clinically its proliferative finger like projections or a cauliflower like growth could be a typical feature towards diagnosis. It’s more common in tobacco user and more predilection in males. The histopathological diagnosis of verrucouscarcinoma is quite difficult and need immense expertise to report a case of verrucous carcinoma. Though verrucous carcinoma is a benign lesion with minimum aggressive potential however long standing cases shows transformation into squamous cell carcinoma. Here in we discussthe clinical and histopathological finding of the case of 80 year old male patient with oral verrucous carcinoma on buccal sulcus as a differential diagnosis with possible etiology, management of the lesion.

Keywords

Verrucous Carcinoma, Buccal Mucosa, Incisional Biopsy, Cauliflower Like Growth.

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S. Leena Sankari ¹, F. Ryhanath Gulshan ², Sudha Jimson ³, K. M. K. Masthan ⁴

Affiliations
1 Professor, Sree Balaji Dental College and Hospital, Bharat Institute of Higher Education (BIHER) Chennai, IN
2 Post Graduate Student, Sree Balaji Dental College and Hospital, Bharat Institute of Higher Education (BIHER) Chennai, IN
3 Reader, Sree Balaji Dental College and Hospital, Bharat Institute of Higher Education (BIHER) Chennai, IN
4 Professor and Head of the Dept., Sree Balaji Dental College and Hospital, Bharat Institute of Higher Education (BIHER) Chennai, IN

Abstract

Human mouth consists of diverse micro-organisms which includes bacteria, viruses, fungi and protozoan. Oral microbiome is unique because of the constant contact of oral cavity with the external environment. Diets, Temperature, pH of saliva are important factors that contribute to the establishment of oral microbiome. The oral microbiome is imperative to health as it causes both oral and systemic diseases. A dysbiotic microflora influences the development of oral diseases like dental caries, periodontal diseases (gingivitis and periodontitis). Promoting a balanced microbiome is the key to maintain or reestablish oral health. Technological advances Iin the recent times have started to unwind the mysteries and complexities of the oral microbiome helping us to gain insights into its role in health and disease states.

Keywords

Microbiome, Microorganism, Disease, Health.

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Sudha Jimson ¹, G. Nishanth ², S. Leena Sankari ³, K. M. K. Masthan ⁴, N. Aravindha Babu ³

Affiliations
1 Reader, Sree Balaji Dental College and Hospital, Bharat Institute of Higher Education (BIHER), Chennai, IN
2 Post Graduate Student, Sree Balaji Dental College and Hospital, Bharat Institute of Higher Education (BIHER), Chennai, IN
3 Professor, Sree Balaji Dental College and Hospital, Bharat Institute of Higher Education (BIHER), Chennai, IN
4 Professor and Head of the Dept., Sree Balaji Dental College and Hospital, Bharat Institute of Higher Education (BIHER), Chennai

Abstract

Oral submucous fibrosis is an incidious, chronic disease stirring any part of oral cavity and sometimes the pharynx. South east Asian counties are proven to be high prevent zones.for oral sub mucous fibrosis.. Areca quid related oral mucosal lesions are potential hazard to an outsized e population worldwide. Commercially freeze dried products such as pan masala, guthka and mawa have high concentration of areca nut per chew and appear to cause osmf more rapidly than by self prepared betel quid that contain smaller amounts of areca nut. These chemicals appear to interact with the molecular processes of deposition and or degradation of extracellular matrix molecules such as collagen causing imbalance in the regular process. Various studies done in the past include osmf as potentially malignant disorder. Understanding the etiopathogenesis of osmf may be beneficial to revert the risk factors thereby minimizing the progress of the disease which is included as the priority in the prevention of disease.

Keywords

OSMF, Areca Nut, Betel Quid.

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Sudha Jimson ¹, M. Parasakthi ², S. Leena Sankari ³, K. M. K. Masthan ³, N. Aravindha Babu ³

Affiliations
1 Reader, Sree Balaji Dental College and Hospital, Bharat Institute of Higher Education (BIHER), Chennai, IN
2 Post Graduate Student, Sree Balaji Dental College and Hospital, Bharat Institute of Higher Education (BIHER), Chennai, IN
3 Sree Balaji Dental College and Hospital, Bharat Institute of Higher Education (BIHER), Chennai, IN

Abstract

Giant cells are often seen in many conditions. Their presence in microscope is of great interest and play a vital role in histopathological diagnosis. They can be classified into several types by various authors. Their formation in physiological and pathological conditions is based on several mechanisms. The physiological giant cells seen in our body are synctiotrophoblasts in placenta, megakaryocytes in bone marrow and osteoclasts in bone. This article attempts to review on the basic mechanisms of formation and histopathology of giant cell associated lesions

Keywords

Giant cell, Langhans Cell, Touton, Osteoclast.

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Sudha Jimson ¹, S. Jimson ², S. Leena Sankari ¹, Lokesh Bhanumurthy ³, A. Julius ⁴

Affiliations
1 Professor, Department of Oral Pathology, Sree Balaji Dental College & Hospital, Chennai, IN
2 Professor & Head, Department of Oral & Maxillofacial Surgery, Tagore Dental College & Hospital, Chennai, IN
3 Reader, Department of Oral & Maxillofacial Surgery, Tagore Dental College & Hospital, Chennai, IN
4 Professor & Head, Department of Biochemistry, Sree Balaji Dental College & Hospital, Chennai, IN

Abstract

Radicular cyst is the common odontogenic inflammatory cyst which arises from the cell rest of malassez. It is asymptomatic and swelling proceeds solely indicating cortical plate expansion radicular cyst is the consequence of pulpal necrosis. The management of radicular cyst is aided by clinical, FNAC and radiographic examination. Diagnosis is confirmed by histopathological examination. Treatment options are based on the extent of the lesion, structure, origin and clinical/systemic condition of the patient. Untreated cyst may expand causing local tissue destruction and further pathological deformity. Management includes non-surgical endodontics and surgical methods like endodontic surgery, decompression, marsupialization or enucleation. This article briefly discusses the clinical features, etiopathogenesis and treatment options for management of radicular cysts.

Keywords

Cyst, MTA, Pathogenesis, Periapical.

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