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V. S. Nade , L. A. Kawale , S. Dwivedi , A. V. Yadav

Abstract

Objective: To investigate the effect of the methanolic extract of Hibiscus rosa sinensis ischolar_mains (H. sinensis) on the central nervous system in mice and rats. Materials and methods: The methanolic extract of H. sinensis was studied on pentobarbital-induced sleeping time, elevated plus maze, hole board test, foot shock-induced aggression, haloperidol-induced catalepsy, lithium-induced head twitches, locomotor activity, acetic acid-induced writhing and hot plate analgesiometer at various doses (50 - 200 mg/kg), intraperitoneally for sedative, anxiolytic, antipsychotic, muscle relaxant and analgesic activities. Results: The extract prolonged pentobarbital-induced sleeping time indicating sedative effect. The extract increased the time spent in open arms and the number of head dips in elevated plus maze and hole board test respectively demonstrating anxiolytic activity. H. sinensis decreased number of fights in foot shock-induced aggression and potentiated haloperidol-induced catalepsy in dose dependent manner showing antipsychotic effect. The extract significantly inhibited head twitches induced by lithium suggesting its inhibitory effect on serotonergic system. The H. sinensis significantly decreased the locomotor activity in dose dependent manner. The extract showed potential analgesic activity in acetic acid-induced writhing and hot plate analgesiometer. The H. sinensis attenuated the behavior mediated by the dopaminergic and serotonergic system and potentiated the GABAergic actions. Conclusion: The results suggest that the methanolic extract of Hibiscus rosa sinensis has potential neuropharmacological activities.

Keywords

Hibiscus Rosa Sinensis, Sedative, Anxiolytic, Antipsychotic, Analgesic, Catalepsy

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S. Dwivedi ¹, S. Kumar ², K. C. Garg ²

Affiliations
1 Banaras Hindu University, Varanasi, 221 005, IN
2 CSIR-National Institute of Science Technology and Development Studies, Dr K.S. Krishnan Marg, New Delhi 110 012, IN

Abstract

An analysis of 17,344 papers published by Indian scientists and indexed by Web of Science in the discipline of organic chemistry and its sub-disciplines during 2004-2013 indicates that the Indian output has increased significantly in the later period. Academic institutions contributed about 46% of the total output followed by the Council of Scientific and Industrial Research (CSIR) with 26% of the total output. The most prolific institutions among them mainly belonging to academic institutions and CSIR contributed about 60% of the total output. The value of citation per paper for most of the prolific institutions was higher than the Indian average. Similar trend was observed for the relative citation impact. Indian researchers in the discipline of organic chemistry published their papers in international journals with impact factor greater than 1. About 11% of the papers published by Indian scientists in the discipline of organic chemistry during 2004-2013 remained uncited.

Keywords

Bibliometric indicators, citation analysis, organic chemistry, scientometrics

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S. K. Pandey ¹, S. Pandey ², S. Dwivedi ¹, N. Bajaj ¹, S. Kunder ³

Affiliations
1 S.S. Medical College Rewa (M.P.), IN
2 Dept. of Pediatrics, S.S. Medical College, Rewa (M.P.), IN
3 Dept. of Zoology, Girls P.G. Degree College Rewa (M.P.), IN

Abstract

Research methodology is the route through which researchers are required to conduct their research. It shows the path through which these researchers formulate their problem and purpose and present their results from the data obtained during the study period. This research design and methodology shows how the research results will be achieved in the end, along with fulfilling the purpose of the study. The purpose of the research method is to satisfy the research plan and the goal prepared by the researcher. Scientific research methods help us collect samples, data and find a solution to a problem.

Keywords

Research Methodology, Sampling Method, Study Design, Odd Ratio.

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S. Pandey ¹, S. Kunder ², N. Bajaj ¹, S. Dwivedi ³, SP. Mahapatra ⁴, D. Pandey ⁵, SK. Pandey ⁶

Affiliations
1 Deptt. of Pediatrics, S.S. Medical College Rewa (M.P.), IN
2 Deptt. of Zoology, Girls P.G. Degree College Rewa (M.P.), IN
3 Deptt. of Anaesthesiology, S.S. Medical College Rewa (M.P.), IN
4 Deptt. of Pharmacology, S.S. Medical College Rewa (M.P.), IN
5 S.S. Medical College Rewa (M.P.), IN
6 Scientist-II, Multi-disciplinary Research Unit, S.S. Medical College Rewa (M.P.), IN

Abstract

An impact factor is a measure of citations to articles published in a journal. A citation is a reference to a specific work cited in another work. The work is a scholarly work such as one in a peer reviewed journal. To find out how much impact of a particular article or author has had by showing that other authors cited work within their own papers. An abstracting and indexing service is an important part of the publishing process. It indexes content at the article level by specifying subject headings at each level and then making them searchable in the product’s database. These services also list other bibliographic elements of journal articles, including author, title and date of publication etc.

Keywords

Impact Factor, Indexing, Abstracting, Citation Metrics, Pubmed.

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