Informatics Publishing Limited

Vaikundam Kannabirran ¹, Subramanian Madhu ², P. Vidhya Priya ³, R. Uthaya ³, Senguttuvan Sivan Mozhi ³

Affiliations
1 Surya School of Pharmacy, Vikravandi, Villupuram, Tamilnadu, IN
2 Kamalaktchi Pandurangan College of Pharmacy, Thiruvannamalai, Tamilnadu, IN
3 Prist University, Department of Biotechnology, Puducherry Campus, Puducherry, IN

Abstract

Dengue fever is a serious threat to global health issues; it leads us to a public health challenge with an economic saddle. Approximately 100 countries are endemic for dengue fever and 40% of the world's population or about 2.5 billion people in the tropical and sub-tropics have an increased risk. It is also known break bone fever, is a selflimited, systematic viral infection transmitted from mosquitoes to humans.. Symptoms include fever, headache, muscle and joint pains, and with a characteristic skin rashes that is similar to measles. In a small proportion of cases, the disease develops into the life-threatening dengue hemorrhagic fever, resulting in bleeding, low levels of blood platelets and blood plasma leakage, or into dengue shock syndrome. To the core of this review are ought to discuss about the symptoms, mechanism of the virus in the host, penetration towards our body, characteristic antibody responses, life cycle, various phases involved in the cycle, efficient vector control strategies, pathogenesis, Diagnosis, ongoing therapies, and its management and prevention.

Keywords

Aedes aegypti, Systematic Viral Infection, Denv-1, Denv-2, Denv- 3, and Denv-4, Symptoms, Nonstructural (NS) Enzyme

Full Text

   

R. Uthaya ¹, Vaikumdam Kannabirran ², Subramanian Madhu , Senguttuvan Sivan Mozhi ³, P. Vidhya Priya ³

Affiliations
1 Prist University, Department of Biotechnology, Puducherry Campus, Puducherry. Surya School of Pharmacy, Vikravandi, Villupuram, Tamilnadu
2 Kamalaktchi Pandurangan College of Pharmacy, Thiruvannamalai, Tamilnadu, IN
3 Prist University, Department of Biotechnology, Puducherry Campus, Puducherry. Surya School of Pharmacy, Vikravandi, Villupuram, Tamilnadu, IN

Abstract

Dengue fever also known as break bone fever, is a self limited, systematic viral infection transmitted between humans by mosquitoes. It leads to a public health challenge with an economic saddle. Its symptoms include fever, headache, muscle and joint pains, and a characteristic skin rash that is similar to measles. In a small proportion of cases, the disease develops into the life-threatening dengue hemorrhagic fever, resulting in bleeding, low levels of blood platelets and blood plasma leakage, or into dengue shock syndrome, where dangerously low blood pressure occurs. Dengue fever is a serious threat to global health issues. Approximately 100 countries are endemic for dengue fever and 40% of the world's population or about 2.5 billion people in the tropical and sub-tropics have an increased risk of catching the disease. So, to the core of the review we are ought to discuss about a wide topics towards the symptoms, Mechanism of the virus in the host, penetration towards our body, Characteristic antibody responses, life cycle, various phases involved in the cycle, efficient vector control strategies, pathogenesis, Diagnosis, ongoing therapies, and its management and prevention. In addition, we ought to suggest at conclusion that would be a better way to research in this type of disease with reviews.

Keywords

Break Bone Fever, Dengue Hemorrhagic Fever, Dengue Shock Syndrome, Flavivirus Vectors

Full Text