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Sekhar, P.
- Transient Gestational Hypothyroidism-Induced Changes in the Pituitary Testicular Axis Differ from that of Neonatal Onset Hypothyroidism
Abstract Views :183 |
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Authors
A. M. J. Sashi
1,
N. S. Venkatesh
1,
P. Sekhar
1,
J. Anbalagan
1,
G. Vengatesh
1,
P. Govindarajulu
1,
M. M. Aruldhas
1
Affiliations
1 Department of Endocrinology, Dr. ALM Post Graduate Institute of Basic Medical Sciences, University of Madras, Taramani Campus, Chennai 600 113, IN
1 Department of Endocrinology, Dr. ALM Post Graduate Institute of Basic Medical Sciences, University of Madras, Taramani Campus, Chennai 600 113, IN
Source
Journal of Endocrinology and Reproduction, Vol 7, No 1&2 (2003), Pagination: 42-42Abstract
Hypogonadism and male infertility associated with congenital hypothyroidism are two important reproductive health problems. Studies emanated from our laboratory and a few others have established thyroid hormone as an important regulator of testicular development, growth, structure and function. Existing literature are centering around the effect of neonatal, prepuberal and puberal onset hypothyroidism on the testis of adult rats.- Gestational Exposure to Chromium Alters the Histoarchitecture of Adult Rat Testis: a Light Microscopic Study
Abstract Views :180 |
PDF Views:0
Authors
P. Sekhar
1,
S. Subramanian
2,
N. S. Venkatesh
2,
A. M. J. Sashi
2,
N. Kalpana
2,
J. Anbalagan
2,
G. Vengatesh
2,
P. Govindarajulu
2,
M. A. Akbarsha
3,
M. M. Aruldhas
2
Affiliations
1 Post Graduate Department of Zoology, Voorhees College, Vellore-632001, IN
2 Department of Endocrinology, University of Madras, Dr. ALM Post Graduate Institute of Basic Medical Sciences, Taramani Campus, Chennai-600113, IN
3 Department of Animal Science, Bharathidasan University, Tiruchirappalli-620024, IN
1 Post Graduate Department of Zoology, Voorhees College, Vellore-632001, IN
2 Department of Endocrinology, University of Madras, Dr. ALM Post Graduate Institute of Basic Medical Sciences, Taramani Campus, Chennai-600113, IN
3 Department of Animal Science, Bharathidasan University, Tiruchirappalli-620024, IN
Source
Journal of Endocrinology and Reproduction, Vol 7, No 1&2 (2003), Pagination: 86-87Abstract
Heavy metals and chemicals are known to cause male infertility. Chromium, an occupational heavy metal pollutant is a wellknown carcinogen with toxic effect on skin, lung and kidney. A few early reports point out the reproductive toxicity of chromium in experimental animals. An extensive study conducted in our laboratory in adult rats and monkeys established that altered prooxidant - antioxidant balance leading to free radical toxicity in the testis as the mechanism underlying the reproductive toxicity of chromium.- Gestational Exposure to Chromium Interferes with Post-Natal Development and Growth of the Thyroid Gland through Altered TSH
Abstract Views :156 |
PDF Views:0
Authors
Affiliations
1 Department of Endocrinology, University of Madras, Dr. ALM Post Graduate Institute of Basic Medical Sciences, Taramani Campus, Chennai-600113, IN
1 Department of Endocrinology, University of Madras, Dr. ALM Post Graduate Institute of Basic Medical Sciences, Taramani Campus, Chennai-600113, IN
Source
Journal of Endocrinology and Reproduction, Vol 7, No 1&2 (2003), Pagination: 87-88Abstract
Chromium is one of the important heavy metal toxicants released into the environment by about 50 industries, which includes leather tanneries, stainless steel welding, and ordinance factory and chrome platting. Though the adverse effect of chromium on skin, lung and reproductive organs are known, its toxic effect on endocrine glands is little known. It is well known that chromium can readily pass through the placental barriers to reach the growing foetus. Recent studies attest the embryo toxicity of gestational exposure to chromium. The thyroid is one of the earliest endocrine organs to develop from the endoderm and its development is regulated by specific transcription factor like TTF-1, TTF-2, Pax-8 and various other growth factors.- Transient Hypothyroidism during the Second Week of Gestation has a Temporal and Region Specific Effect on the Histoarchitecture of the Epididymis at Prepuberal, Puberal and Adult Rats
Abstract Views :183 |
PDF Views:0
Authors
A. M. J. Sashi
1,
N. S. Venkatesh
1,
G. Vengatesh
1,
P. Sekhar
1,
J. Anbalagan
1,
N. Kala
1,
P. Govindarajulu
1,
M. A. Akbarsha
2,
M. M. Aruldhas
1
Affiliations
1 Department of Endocrinology, Dr. ALM Post Graduate Institute of Basic Medical Sciences, University of Madras, Taramani Campus, Chennai-600113, IN
2 Department of Animal Science, Bharathidasan University, Tiruchirappalli-620024, IN
1 Department of Endocrinology, Dr. ALM Post Graduate Institute of Basic Medical Sciences, University of Madras, Taramani Campus, Chennai-600113, IN
2 Department of Animal Science, Bharathidasan University, Tiruchirappalli-620024, IN