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Deepesh, P.
- In Vitro Anticancer Study of Bioactive Compound Isolated from Musa Extract (Musa acuminata)
Abstract Views :395 |
PDF Views:0
Authors
Affiliations
1 Associate Professor, Molecular Diagnostics and Bacterial Pathogenomics Research Laboratory, Department of Biotechnology, Bannari Amman Institute Technology, Sathyamangalam, Erode District, Tamil Nadu, IN
2 Research Associate cum Assistant Professor, Molecular Diagnostics and Bacterial Pathogenomics Research Laboratory, Department of Biotechnology, Bannari Amman Institute Technology, Sathyamangalam, Erode District, Tamil Nadu, IN
3 III Year Biotech Students, Molecular Diagnostics and Bacterial Pathogenomics Research Laboratory, Department of Biotechnology, Bannari Amman Institute Technology, Sathyamangalam, Erode District, Tamil Nadu, IN
1 Associate Professor, Molecular Diagnostics and Bacterial Pathogenomics Research Laboratory, Department of Biotechnology, Bannari Amman Institute Technology, Sathyamangalam, Erode District, Tamil Nadu, IN
2 Research Associate cum Assistant Professor, Molecular Diagnostics and Bacterial Pathogenomics Research Laboratory, Department of Biotechnology, Bannari Amman Institute Technology, Sathyamangalam, Erode District, Tamil Nadu, IN
3 III Year Biotech Students, Molecular Diagnostics and Bacterial Pathogenomics Research Laboratory, Department of Biotechnology, Bannari Amman Institute Technology, Sathyamangalam, Erode District, Tamil Nadu, IN
Source
Indian Journal of Public Health Research & Development, Vol 11, No 1 (2020), Pagination: 340-346Abstract
Banana tree being one of the most economically important tree worldwide is cut once the fruits are harvested. However other parts of the tree are used in medicine worldwide. In this study, the flower extract of Musa acuminatais extracted by maceration with methanol and the phenolic and aliphatic compounds present in the flower extract is identified using GC-MS analysis. Phytochemical screening of the banana extract showed the presence of alkaloids, phlobatanning, triterpanoids, flavanoids, lipids, steroids and terpenoids. Potent antibacterial activity is observed from the flower extract against the tested gram positive and negative bacteria. Anticancer activity of the flower extract is assessed on the cervical cancer cell line HeLa. MTT assay is used to evaluate the antiproliferative effects. This study concluded that the economically important Musa acuminatais widely used in anticancer studies worldwide.Keywords
Musa acuminata, Phenolic Compounds, GC-MS Analysis, Phytochemical Screening, Antibacterial Activity, MTT Assay.
- Antibacterial and in vitro Anticancer Study of Methanol Extracts of Clitoria ternatea Leaves
Abstract Views :309 |
PDF Views:401
Authors
Arunava Das
1,
G. Shanmuga Priya
1,
S. Soundariya
1,
P. Deepesh
1,
Aileen Rose Edwin
1,
E. Vihashinee
1,
A. Rubiga
1,
S. Megavarthini
1,
R. Eswaran
1,
J. Bindhu
1
Affiliations
1 Molecular Diagnostics & Biomolecule Characterization Lab, Department of Biotechnology, Bannari Amman Institute of Technology, Sathyamangalam – 638401, Erode, IN
1 Molecular Diagnostics & Biomolecule Characterization Lab, Department of Biotechnology, Bannari Amman Institute of Technology, Sathyamangalam – 638401, Erode, IN
Source
Journal of Natural Remedies, Vol 20, No 2 (2020), Pagination: 96-102Abstract
Clitoria ternatea is often known as butterfly pea plant by the natives and is one of the major plants used in Ayurveda and traditional medicine worldwide. It is also used in food and cosmetic industries for various purposes. In this study, methanol leaf extract of Clitoria ternatea was studied for its antibacterial and in vitro anticancer study against human promyelocytic leukemia cells (HL60). Secondary metabolites like alkaloids, phlobatannin, triterpenoids, flavonoids, lipids, steroids, terpenoids, tannins and glycosides are identified in the extract by phytochemical screening. Leaf extract showed the presence of ethers and carboxylic acid groups (GCMS analysis). The leaf extract showed resistance against Salmonella typhi. Thus, from this study it can be concluded Clitoria ternatea leaves methanol extract has bioactive compounds showing anticancer activity against HL60 cells.Keywords
Antibacterial Activity, Anticancer Activity, Clitoria ternatea, GC-MS Analysis, Phytochemical Screening, MTT Assay.Full Text
References
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