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Praveen Kumar, P. K.
- Studies on the Effects of Ph and Incubation Period on Protease Production by bacillus spp. Using Groundnut Cake and Wheat Bran
Abstract Views :436 |
PDF Views:114
Authors
Affiliations
1 Department of Industrial Biotechnology, Bharath University, Chennai-600 073, IN
2 Chemical Engineering Department, Anna University, Chennai-600 025, IN
3 Department of Biotechnology, St. Peter’s Engineering College, Chennai-54, IN
1 Department of Industrial Biotechnology, Bharath University, Chennai-600 073, IN
2 Chemical Engineering Department, Anna University, Chennai-600 025, IN
3 Department of Biotechnology, St. Peter’s Engineering College, Chennai-54, IN
Source
Indian Journal of Science and Technology, Vol 1, No 4 (2008), Pagination: 1-4Abstract
The production of alkaline protease by Bacillus licheniformis (MTCC 1483) and Bacillus subtilis of indigenous isolates using cheapest sources- groundnut cake (N2 Source) and wheat bran (C source) was studied. The proteolytic activity was found maximum at 72 hr of the culture for both the bacterial types but the pH of the medium for maximal enzyme production varied as 9 for Bacillus licheniformis and as 8 for Bacillus subtilis. Thus investigations of this study reveal the possibility of employing cheapest nutrient source for microbial proteases that can be used on a commercial scale.Keywords
pH, Protease, Bacillus licheniformis, B. subtilis, Groundnut Cake, Wheat BranFull Text
References
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- A Computational Analysis to Study the Application of Lipid Nanotechnology in the Field of Drug Delivery to Treat Liver Diseases
Abstract Views :262 |
PDF Views:0
Authors
Affiliations
1 Department of Biotechnology, Sri Venkateswara College of Engineering, Sriperumbudur, IN
1 Department of Biotechnology, Sri Venkateswara College of Engineering, Sriperumbudur, IN
Source
Research Journal of Engineering and Technology, Vol 4, No 4 (2013), Pagination: 284-287Abstract
The Present Study is to analyse the targeted delivery of Ursodiol, a drug used in the treatment of Primary Sclerosing Cholangitis (PSC) using Lipid Bilayer Nano-Particles or Solid Lipid Nano Particles(SLNPs) which is taken for insilico binding studies with various 4 different liver receptors. 3 Solid Lipid Nano Particles are chosen and Binding Efficiency of the Drug with Solid Lipid Nano Particles are Studied Using DFT Analysis and FEM Analysis. It was seen that the complete drug binding is seen in Small Unilamellar Vessicle (SUV). Chosen Liver Receptors with Ursodiol of the SUV are checked for binding studies using AutoDock 4. The Study revealed that Liver X Receptor has a greater efficiency in binding with the Solid Lipid Nano Particles.Keywords
Ursodiol, Solid Lipid Nano Particles, Small Unilamellar Vessicle, Liver Receptors.
- In-Silico Analysis of Targeted Drug Delivery to Hepatic Cells using Lipid Nano-Particles to Treat Liver Diseases
Abstract Views :289 |
PDF Views:2
Authors
Affiliations
1 Department of Biotechnology, Sri Venkateswara College of Engineering, Sriperumbudur, Chennai, IN
2 Department of Bioinformatics and ARIS Cell, Madras Veterinary College, Chennai, IN
1 Department of Biotechnology, Sri Venkateswara College of Engineering, Sriperumbudur, Chennai, IN
2 Department of Bioinformatics and ARIS Cell, Madras Veterinary College, Chennai, IN