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Malekar, Nikita S.
- An overview on Trends and Development of Niosomes as Drug Delivery
Abstract Views :406 |
PDF Views:0
Authors
Affiliations
1 Department of Pharmaceutics, R. G. Sapkal College of Pharmacy, Anjenari, Nashik-422213, Maharashtra, IN
2 Department of Quality Assurance Techniques, R. G. Sapkal College of Pharmacy, Anjenari, Nashik-422213, Maharashtra, IN
3 Department of Pharmaceutical Chemistry, R.G. Sapkal College of Pharmacy, Anjenari, Nashik-422213, Maharashtra, IN
1 Department of Pharmaceutics, R. G. Sapkal College of Pharmacy, Anjenari, Nashik-422213, Maharashtra, IN
2 Department of Quality Assurance Techniques, R. G. Sapkal College of Pharmacy, Anjenari, Nashik-422213, Maharashtra, IN
3 Department of Pharmaceutical Chemistry, R.G. Sapkal College of Pharmacy, Anjenari, Nashik-422213, Maharashtra, IN
Source
Research Journal of Topical and Cosmetic Sciences, Vol 7, No 2 (2016), Pagination: 79-85Abstract
Niosomes or non ionic surfactant are microscopic lamellar structures which may be unilamellar or multilamellar. These are amphiphillic in nature, hence capable of entrapping both hydrophilic and lipophilic drugs for their controlled delivery. Niosomes are formulated by hydration of the lipid by the aqueous phase which may be either single surfactant or a mixture of surfactant with cholesterol. Stability of niosomes is greater as compared with other novel drug delivery techniques. Niosomes are widely used for delivery of many drugs especially in treatment of life threatening diseases, site specific targeting can be achieved with niosomes, and they are also used in diagnostic imaging purpose. This study is based upon the recent advances by which niosomes can be formulated and their application in controlled and effective delivery of variousdrugs. Niosomes represent a promising drug delivery module. They present a structure similar to liposome and hence they can represent alternative vesicular systems with respect to liposomes, due to the niosome ability to encapsulate different type of drugs within their multi environmental structure. Niosomes are thoughts to be better candidate's drug delivery as compared to liposomes due to various factors like cost, stability etc. Various types of drug deliveries can be possible using niosomes like targeting, ophthalmic, topical, parenteral, etc.Keywords
Niosomes, Drug Delivery, Routes of Administrations, Applications.- In- Situ Nasal Gel: A Review
Abstract Views :200 |
PDF Views:1
Authors
Affiliations
1 Department of Quality Assurance Techniques, R. G. Sapkal College of Pharmacy, Anjenari, Nashik-422213, Maharashtra, IN
2 Department of Pharmaceutics, R. G. Sapkal College of Pharmacy, Anjenari, Nashik-422213, Maharashtra, IN
3 Department of Pharmaceutical Chemistry, R.G.Sapkal College of Pharmacy, Anjenari, Nashik-422213, Maharashtra, IN
1 Department of Quality Assurance Techniques, R. G. Sapkal College of Pharmacy, Anjenari, Nashik-422213, Maharashtra, IN
2 Department of Pharmaceutics, R. G. Sapkal College of Pharmacy, Anjenari, Nashik-422213, Maharashtra, IN
3 Department of Pharmaceutical Chemistry, R.G.Sapkal College of Pharmacy, Anjenari, Nashik-422213, Maharashtra, IN
Source
Research Journal of Pharmaceutical Dosage Form and Technology, Vol 7, No 4 (2015), Pagination: 285-293Abstract
Nasal therapy also called "Nasya Karma" has been recognized form of treatment in the Ayurvedic. System of Indian Medicine. Nowadays many drugs have better systemic bioavailability through nasal route as compared to oral administration. The nose is also considered an attractive route for needle-free vaccination and for systemic drug delivery, especially when rapid absorption and effect are desired. The nasal delivery is a feasible alternative to oral or parenteral administration for some drug because of the high permeability of the nasal epithelium, rapid drug absorption across this membrane and avidance of first pass metabolism. Prolonged drug delivery can be achieved by various new dosage forms like in-situ gel. In-situ forming polymeric formulation are drug delivery system that is in sol form before administration in the body, but once administered, undergoes gelation in-situ to form a gel. In-situ nasal drug delivery system is the type of mucoadhesive drug delivery system. Now a days insitu gel has been used as vehicle for the drug delivery of the drug for both local treatment and systemic effect. In-situ nasal gel drug delivery system is advantageous over the conventional drug delivery system like sustained and prolonged release of drug, reduced frequency of administration, improved patient compliance and comfort.Keywords
Nasal Drug Delivery, Nasal In-Situ Gel, Mucoadhesive Drug Delivery System.- Development of Naratriptan Hydrochloride In-Situ Nasal Gel
Abstract Views :240 |
PDF Views:3
Authors
Nikita S. Malekar
1,
Sheetal B. Gondkar
1,
Bhushan A. Bhairav
1,
Pinak S. Paralkar
2,
Ravindra B. Saudagar
3
Affiliations
1 Department of Quality Assurance Techniques, KCT’S, Ravindra Gambhirrao Sapkal College of Pharmacy, Anjaneri, Nashik-422213, Maharashtra, IN
2 Department of Pharmaceutics , KCT’S, Ravindra Gambhirrao Sapkal College of Pharmacy, Anjaneri, Nashik-422213, Maharashtra, IN
3 Department of Pharmaceutical Chemistry, KCT’S, Ravindra Gambhirrao College of Pharmacy, Anjaneri, Nashik-422213, Maharashtra, IN
1 Department of Quality Assurance Techniques, KCT’S, Ravindra Gambhirrao Sapkal College of Pharmacy, Anjaneri, Nashik-422213, Maharashtra, IN
2 Department of Pharmaceutics , KCT’S, Ravindra Gambhirrao Sapkal College of Pharmacy, Anjaneri, Nashik-422213, Maharashtra, IN
3 Department of Pharmaceutical Chemistry, KCT’S, Ravindra Gambhirrao College of Pharmacy, Anjaneri, Nashik-422213, Maharashtra, IN