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Udupa, N.
- Evaluation of Outcomes of Breast Cancer with a Special Focus on Economic Impact and Quality of Life - a Pilot Study
Abstract Views :194 |
PDF Views:84
Authors
Affiliations
1 Manipal College of pharmaceutical Sciences, Madhav Nagar, Manipal 576104, IN
2 Department of Radiation Oncology,Manipal Hospital ,Old Air Port Road, Bangalore, IN
3 University of Michigan College of Pharmacy, Church Street, Ann Arbor, Michigan, US
1 Manipal College of pharmaceutical Sciences, Madhav Nagar, Manipal 576104, IN
2 Department of Radiation Oncology,Manipal Hospital ,Old Air Port Road, Bangalore, IN
3 University of Michigan College of Pharmacy, Church Street, Ann Arbor, Michigan, US
Source
Journal of Pharmaceutical Research, Vol 11, No 4 (2012), Pagination: 118-122Abstract
Objectives: A pilot study is conducted to evaluate the outcomes of pharmacological management of breast cancer in a hospital setting. Method: Patient interviews were held to study the economic out come and standardized tool EORTC QLQ C 30 and its breast specific module EORTC QLQ BR 23 was utilized to measure the quality of life. Fifty two subjects diagnosed at different stages of the disease were studied. Results: The respondent's age ranged between 28-67 years, mean age 47.05(SD=9.33). The educational status varied from illiterate to university, the illiterate (28.84%), primary education (25.0%), class 5-10 (36.53%), intermediate undergraduate (7.69%), and post graduate studies (1.92%). Most of the participants (84.6%) were married and cohabiting with their spouses and few (15.38%) were widowed. The TNM staging of breast cancer was observed as first stage (none), stage II (42.3%), stage III (40.4%), and stage IV (15.4%), stage unknown (1.9%). All patients were treated with a multimodality approach for management. The cost analysis revealed that there are significant, differences among different modalities of treatments (Rs.1.01 lakh, Rs.1.17 lakh, Rs.1.53 lakh). The average direct cost of treatment for group I (4cycles of AC chemo, Rs.1.01 lakh), and group II (6 cycles of chemo Rs.1.17 lakh) and group III (8 cycles of chemo Rs.1.53 lakh).The quality of life study revealed that there are differences in the functional scales as well as symptoms scales among the patients treated with different treatment regimens. Discussions and Implications: Breast cancer is a very commonly diagnosed cancer among women all over the world .Early diagnosis and timely treatment can prolong the disease free survival of such patients with an improved quality of life. This research revealed different approaches of treatment for breast cancer management, in a private hospital setting in south India and the cost involved in three approaches, and their quality of life .The follow up after one year showed that most of them are leading a disease free life with better quality of life.Keywords
Breast Cancer, Outcomes Evaluation, Quality of Life, Cost Analysis.- Analytical Method Development and Validation for Dipyridamole
Abstract Views :229 |
PDF Views:118
Authors
Source
Asian Journal of Pharmaceutical Research and Health Care, Vol 2, No 4 (2010), Pagination: 333-338Abstract
A sensitive, specific, precise and cost effective High Performance Liquid Chromatographic method of analysis for dipyridamole in presence of its degradation products is developed and validated. The method employed Targa C8 column i.e., (250 X 4.6 mm 5 μm particle size) column as stationary phase. The mobile phase consists of acetonitrile and pH3.0 buffer in the ratio 35:65 %. It is pumped through the chromatographic system at a flow rate of 1.2 ml /min. The UV detector is operated at 282 nm. This system was found to give good resolution between dipyridamole and its degradation products. Method was validated as per ICH guidelines.Keywords
HPLC, Dipyridamole, UV Detector, Targa C8 Column.- An Overview on Fast Dissolving Oral Films
Abstract Views :222 |
PDF Views:0
Authors
Affiliations
1 Manipal College of Pharmaceutical Sciences, Manipal University, Manipal, IN
2 Sree Siddaganga College of Pharmacy, Thumkur, IN
1 Manipal College of Pharmaceutical Sciences, Manipal University, Manipal, IN
2 Sree Siddaganga College of Pharmacy, Thumkur, IN
Source
Asian Journal of Pharmacy and Technology, Vol 5, No 3 (2015), Pagination: 129-137Abstract
Research and developments in oral drug delivery has evolved to changeover of solid dosage forms from conventional solid tablets/capsules to mouth dissolving drug delivery system (MDDS). Intension behind the development of MDDS was to provide the patients with more conventional means of taking their medication. But in MDDS, dissolution of drug in saliva offers the oral transmucosal absorption of the drug to reach to the systemic circulation. Concept of orotransmucosal drug delivery results into various dosage forms which allows orotransmucosal absorption of the drug. Oral strip is the thin film fabricated using hydrophilic polymers that rapidly dissolves beneath the tongue or in buccal cavity and dissolved drug gets absorbed through the oral mucosal surface to reach to the systemic circulation. Here in this review, formulation consideration, manufacturing, physical evaluation of oral films have been discussed.Keywords
Oral Films, Transmucosal, MDDS, Hydrophilic Polymers, Orotransmucosal.- Knowledge and Attitude of Ayurvedic Physicians Towards Adverse Drug Reactions and Reporting Methods in Udupi Region
Abstract Views :208 |
PDF Views:0
Authors
Affiliations
1 Department of Pharmacy Management, Manipal College of Pharmaceutical Sciences, Manipal University, Manipal, IN
2 Manipal University, Manipal, IN
1 Department of Pharmacy Management, Manipal College of Pharmaceutical Sciences, Manipal University, Manipal, IN
2 Manipal University, Manipal, IN
Source
Research Journal of Pharmacy and Technology, Vol 11, No 1 (2018), Pagination: 117-120Abstract
Introduction: Patient safety is of utmost important in any system of medicine. There is a well-established pharmacovigilance system with allopathic drugs and the ADRs reporting methods are known by allopathic physicians but the same scenario is not with ayurvedic medicines. Objective: To access the knowledge and attitude of ayurvedic physicians with respect to adverse drug reactions caused using ayurvedic medicines and reporting methods. Methodology: A survey among the ayurvedic physicians with the questionnaire was conducted. Results: The mean age of the respondents was 37.12 + 10.24. Of total 33 respondents 15 (45.5%) have observed ADRs in their practice. 25 (75.7%) of the respondents stated that they were aware of all the reporting methods whereas 8 (24.3%) of the respondents were not aware about reporting methods. Conclusion: The finding of this study indicates the need for awareness about the ayurvedic medicines adverse drug reactions and reporting methods among ayurvedic physicians. AYUSH may conduct a few training sessions or programs exclusively on adverse drug reactions and its reporting methods and credit hours can be awarded to the participants. A few more such studies and research are warranted to get a larger picture about knowledge and attitude of physicians towards adverse drug reactions.Keywords
Ayurveda, Physicians, ADR, Reporting Methods, Pharmacovigilance.References
- Manjunath Ajanal, Shradda Nayak, Buduru Sreenivasa Prasad, and Avinash Kadam. Adverse drug reaction and concepts of drug safety in Ayurveda: An overview. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930110/.
- Davyson de L. Moreira, Sabrina Schaaf Teixeira, Maria Helena D. Monteiro, Ana Cecilia A.X. De-Oliveira, Francisco J.R. Paumgartten. Traditional use and safety of herbal medicines. http://dx.doi.org/10.1016/j.bjp.2014.03.006.
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- Mahmood Hilal. Sawsan Hilal. Knowledge, attitude, and utilization of herbal medicines by physicians in the Kingdom of Bahrain: A cross-sectional study. http://www.sciencedirect.com/ science/article/pii/S1815385216300438.
- Neha Soni, Joshi PK, Rout OP and Soni BK. Pharmacovigilance: Future Need of Ayurveda. http://ijapc.com/volume5-second-issue/V5-I2-44-p-313-324.pdf.
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- AYUSH doctors available. Health and Ministry Welfare Secretariat. http://www.karnataka.gov.in/hfwsecretariat/Pages/AYUSH-DOCTORS-UDUPI.aspx.
- Legislation Limbo on e-Pharmacies in India
Abstract Views :274 |
PDF Views:75
Authors
Affiliations
1 Department of Pharmacy Management, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal 576 104, IN
1 Department of Pharmacy Management, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal 576 104, IN
Source
Current Science, Vol 117, No 9 (2019), Pagination: 1406-1407Abstract
In the era of digitalization and electronic empowerment, every person has a freedom to procure what they want with a click of the button. Medicines are no exception. Evolution of e-pharmacies seems to be a logical progression of medicine and technology. However, there is a need to have an in-depth analysis of its functioning and possible medico-legal issues that might prop-up.References
- Kahan, S. E., Seftel, A. D., Resnick, M. I., Sildenafil and the Internet. J. Urol., 2000, 163, 919–923.
- WHO medicines strategy: framework for action in essential drugs and medicines policy 2000–2003, WHO, Geneva.
- The Pharmacists goes online. http:// timesofindia.indiatimes.com/india/The-pharmacist-goes-online/article show/47228104.cms (accessed on 1–28 September 2018).
- Government gears up for e-pharmacies. http://www.livemint.com/Politics/9hMPyMKYHTJSu5VVPRJmWO/Government-gears-up-for-epharmacies.html (accessed on 1–28 September 2018).
- Legality of selling medicines online in India. http://blog.ipleaders.in/legality-of-selling-medicines-online-in-india/ (accessed on 1–28 September 2018).
- MCI letter dated 30.1.2015, No. MCI211(2) (Gen.)/2014/Ethics./155202. Model prescription format for the purpose of making prescription by the Registered Medical Practitioners.
- Verified pharmacy program. https:// nabp.pharmacy/programs/verified-pharmacy-program/ (accessed on 1–28 September 2018).
- http://www.financialexpress.com/article/pharma/latest-updates/dcgi-to-formulate-guidelines-for-e-commerce-marketplace-to-ensure-safety-of-consumers/86732/ (accessed on 15 November 2018).
- Opposed to online pharmacy, chemists observe total bandh. http://indiatoday.intoday.in/story/opposed-to-online-pharmacy-chemists-observe-total-bandh/1/498-830.html (accessed on 15 November 2018).
- NetMeds goes Pan India. http://www.thehindu.com/business/Industry/netmeds-goes-panindia/article7519152.ece (accessed on 1 December 2018).
- Delhi High Court directs govt to stop sale of drugs through e-pharmacies. http://www.pharmabiz.com/NewsDetails.aspx?aid=112821&sid=2 (accessed on 17 December 2018).
- DTAB approves regulatory provisions for online medicine sales; mandatory registration, rigorous monitoring in offing. http://www.pharmabiz.com/News-Details.aspx?aid=112836&sid=1 (accessed on 17 December 2018).
- Madras High Court imposes blanket ban on sale of medicines through e-pharmacies; http://www.pharmabiz.com/News-Details.aspx?aid=112908&sid=2 (accessed on 17 December 2018).