- S. Jayakumari
- V. Ravichandiran
- Arun Kumar Singh
- A. Vijaya Lakshmi
- Ranjit Singh
- B. Rathore
- Sanjay Ragala
- Mahendra Singh
- A. Vijayalakshmi
- Sanjay Ragela
- S. Ramamoorthy
- J. Srikanth
- Armstrong
- Ravichandran
- Jeyakumari
- Hemalatha
- Vijayalakshmi
- P. Jasmine Shiney
- Biplab Paul
- S. Rashmi
- Nivethitha
- Segu Prathyusha
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z All
Velraj, Malarkodi
- Antiinflammatory Activity of Adenanthera pavonina Linn. Leaves
Authors
Source
Journal of Natural Remedies, Vol 12, No 1 (2012), Pagination: 56-62Abstract
Antiinflammatory activity of Adenanthera pavonina Linn. leaves were evaluated using formalin induced rat paw oedema model for acute inflammation and cotton pellet granuloma model for chronic inflammation. The leaves of the plant was extracted with methanol by cold maceration method. The methanolic extract was fractionated with water. The extract and its aqueous fraction were screened for its anti inflammatory activity at the dose levels of 200mg/kg and 400mg/kg. Compared with control both showed significant activity against acute and chronic inflammation. Aqueous fraction of methanolic extract significantly inhibit the paw oedema in acute model and granuloma formation in chronic model with respect to the methanolic extract. The results indicates that the antiinfammatory activity of Adenanthera pavonina leaf extract could be through a inhibition of elevated prostaglandin biosynthesis and reduction of proliferative mass inflammed cells.The present results of anti inflammatory activity supports the folklore claim of Adenanthera pavonina leaves.Keywords
Adenanthera pavonina, Formalin,cotton Pellet Granuloma, Anti Inflammatory- Standardization and Preliminary Phytochemical Studies on the Bark of Madhuca indica J.F.G. Mel
Authors
1 Vels University, School of Pharmaceutical Sciences, Department of Pharmacognosy, Old Pallavaram, Chennai-116, IN
2 Vels University, School of Pharmaceutical Sciences, Department of Pharmacognosy, Old Pallavaram, Chennai-116, IN
Source
Research Journal of Pharmacognosy and Phytochemistry, Vol 3, No 5 (2011), Pagination: 221-224Abstract
Madhuca indica J.F.G. mel belongs to the family "Sapotaceae". It is a much valued herbal medicine used for Rheumatism, Ulcers, itches, bleeding, spongy gums, tonsillitis and diabetes mellitus. The present study report its anatomical, microscopical, quantitative characters, powder microscopy, histochemical, fluorescence analysis, physiochemical standards, preliminary phytochemical standards and thin layer chromatography. The study revealed important diagnostic character which can be used for identification of the plant.
Keywords
Madhuca indica, Transverse Longitudinal Section, Radial Longitudinal Section.- Free Radical Scavenging Activity of Scindapsus officinalis Fruits
Authors
1 Dept. of Pharmacognosy, Vels College of Pharmacy, Pallavaram, Chennai-600 117, IN
2 Department of Pharmacognosy, Vels College of Pharmacy, Pallavaram, Chennai-600 117, IN
Source
Research Journal of Pharmacognosy and Phytochemistry, Vol 2, No 4 (2010), Pagination: 280-283Abstract
In the present study, coarse powder of Scindapsus officinalis (Roxb.) Schott. fruit was extracted successively using hexane, chloroform, ethyl acetate and 50% ethanol. The ethyl acetate and 50% ethanolic extracts were investigated for its antioxidant activity by using nitric oxide and DPPH radical scavenging methods. The IC50 value was also calculated. Ascorbic acid was used as a standard. Both 50% ethanolic and ethyl acetate extract were found to exert concentration dependent free radical scavenging activity but former extract was more effective than the later on. The highest free radical scavenging activity by Scindapsus officinalis fruit extracts was observed at concentration of 1000 μg/ml.Keywords
Scindapsus officinalis (Roxb.) Schott., Antioxidant, Free Radicals, IC50 Value.- Antidepressant-Like Effects of the Ethanolic Extract of Albizzia lebbeck (Linn) Leaves in Animal Models of Depression
Authors
1 Department of Pharmacognosy, Vels School of Pharmaceutical Sciences, Vels University, Pallavaram, Chennai–117, Tamil Nadu, IN
2 Department of Pharmacognosy, Vels School of Pharmaceutical Sciences, Vels University, Pallavaram, Chennai-117, Tamil Nadu, IN
3 Department of Pharmacology, Sri Ramachandra College of Pharmacy, Sri Ramachandra University, Porur, Chennai-600116, Tamilnadu, IN
Source
Research Journal of Pharmacognosy and Phytochemistry, Vol 2, No 1 (2010), Pagination: 30-33Abstract
The present study was designed to investigate the antidepressant effects of Albizzia lebbeck leaves in various animal depression models. The alcoholic extract (70% v/v ethanol) of Albizzia lebbeck leaves (200 and 400 mg/kg. p.o) was administered once daily for seven successive days to separate groups of young male swiss albino mice. The immobility periods of control and treated mice were recorded in two behavioral despair models forced swim test (FST), tail suspension test (TST) and the effect of extract on locomotor function of mice was studied using actophotometer. The antidepressant-like effect of tested drug was compared to that of imipramine (15 mg/kg. p.o) and fluoxetine (20mg/kg.p.o). The leaf extract at doses of 200 and 400 mg/kg significantly decreased the duration of immobility time in a dose dependent manner in both FST and TST.
The extract did not show significant effect on locomotor activity of mice. The efficacy of tested extract was found to be comparable to that of imipramine and fluoxetine. Our results suggested that the ethanolic extract of Albizzia lebbeck leaves exerts antidepressant-like effect.
Keywords
Albizzia lebbeck, Depression, Forced Swim Test, Tail Suspension Test.- Pharmacognostical and Preliminary Phytochemical Studies on the Stem Bark of Soymida febrifuga (Roxb)
Authors
1 Department of Pharmacognosy, VELS College of Pharmacy, VELS University, Pallavaram, Chennai-600 043, Tamil Nadu, IN
2 Department of Pharmacology, Sri Ramachandra College of Pharmacy, Sri Ramachandra University, Porur, Chennai-600 116, Tamil Nadu, IN
Source
Research Journal of Pharmacognosy and Phytochemistry, Vol 1, No 3 (2009), Pagination: 213-216Abstract
Soymida febrifuga is commonly known as Shem in Tamil and Indian red wood in English. In Ayurveda the bark is used as a good cure for ulcer, leprosy and dysentery. In unani the bark is used as an astringent to the bowel and useful in fever. The bark is also used in vaginal infection, rheumatic swellings, oedema, wounds, dental problems, uterine bleeding and malarial fever. There was no report on the pharmacognostic study of the plant and hence the present investigation deals with the anatomical, microscopical, powder microscopy, physio-chemical, fluorescence analysis, Thin layer chromatography and high performance thin layer chromatography. The study revealed the presence of drugs of calcium oxalate, tannins dilated phloem rays, sieve elements and schlerids. Phytochemical studies showed the presence of steroids, terpenoids, flavanoids and tannins.
Keywords
Soymida febrifuga, TLS, RLS.- Biosynthesis of Silver Nano Particles from the Ethanolic Extract Fruits of Mallotus phillipensis
Authors
1 Department of Pharmacognosy, School of Pharmaceutical Sciences, Vels University (VISTAS), Pallavaram, Chennai – 600117, IN
Source
Research Journal of Pharmacy and Technology, Vol 10, No 1 (2017), Pagination: 21-25Abstract
Objective: To develop a novel approach for the green synthesis of silver nanoparticles using Ethanolic extract of fruits of Mallotus phillipensis. Characterizations were determined by using ultraviolet-visible (UV-Vis) spectrophotometry, FTIR, scanning electron microscopy (SEM), and X-ray diffraction. The UV results showed the maximum absorption peak at range of 300-400nm. FTIR Showed the Presence of halides group, aliphatic amines group, alkenes group, alkynes, alcohols and phenol Groups. SEM showed the formation of silver nanoparticles with an average size of 30 - 100 nm. The typical XRD pattern revealed that the sample contains a mixed phase (cubic and hexagonal) structures of silver nanoparticles.Keywords
Mallotus phillipensis, UV, FTIR, SEM and XRD.- Phytochemical Analysis by HR-LCMS and In vitro Anti-diabetic Potential of Michelia champaca Bark
Authors
1 Department of Pharmacognosy, School of Pharmacy, GNITC, Hyderabad – 501506, Telangana Department of Pharmacognosy, VELS Institute of Science, Technology and Advanced studies, Chennai – 600117, Tamil Nadu, IN
2 Department of Pharmacognosy, VELS Institute of Science, Technology and Advanced studies, Chennai – 600117, Tamil Nadu, IN
Source
Journal of Natural Remedies, Vol 22, No 3 (2022), Pagination: 432 - 439Abstract
The current analysis was aimed to study the phytochemical profile and in vitro antidiabetic capacity of HEMC bark. HR-LCMS1 was used to identify the phytochemicals present in the extract. The outcomes of HR-LCMS showed the presence of 15 phytochemical compounds. DL-Carnitine, Catechin, D-α-Tocopherol, Colchicine, Myricetin, Epicatechin, Quercetin, Epigallocatechin gallate, Quercetin-3β-D-glucoside, Kaempferol, Sorbic acid, Apocynin, Epigallocatechin gallate, myricetin 3-O-beta-D-galactopyranoside, Naringeninchalcone are the main compounds identified. The inhibition of enzymes like α-amylase and α-glucosidase delays the rate of glucose absorption thus reducing blood glucose levels in the experimental models. The IC50 values of α-amylase and α-glucosidase inhibitory activity of HEMC were acquired to be 88.65 μg/mL and 71.28 μg/mL correspondingly. Positive control acarbose displayed IC50 assessment of 52.94 μg/mL and 50.01 μg/mL correspondingly. Consequently, the current study confirms that HEMC had remarkable antidiabetic activity and hence holds future potential as nutraceuticals in the treatment of diabetes and related ailments.
Keywords
HR – LCMS, Antidiabetic, Michelia champaca, Bark, α-amylase, α-glucosidase.References
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