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Kapoor, M.
- Anti-asthmatic & Anti-allergic Activity of Lagenaria siceraria Mol. Standley
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Journal of Natural Remedies, Vol 12, No 1 (2012), Pagination: 72-76Abstract
The present attempt was aimed to evaluate the Anti-asthmatic and anti allergic activity of the aqueous extract of Lagenaria siceraria leaf (LSA) using various animal models like histamine and acetylcholine induced bronchoconstriction in Guinea pigs, compound 48/80 induced mast cell degranulation in rats and paw edema in mice. LSA exhibited significant and dose dependent bronchodilatory activity at the doses of 150 and 300 mg/kg intraperitonially (i.p.). LSA at the concentrations of 10, 20 and 30 μg/ml significantly inhibited compound 48/80 induced mast cell degranulation. The anti inflammatory activity was observed at the doses of 50, 75 and 100 mg/kg (i.p.) against compound 48/80 induced paw edema in rats. These results prove the traditional claim of the drug in treatment of asthmatic disorders.Keywords
Lagenaria siceraria Mol. Standley, Bronchoconstriction, Compound 48/80, Mast Cell Stabilization, Paw Edema- National Cardiopulmonary Resuscitation Guidelines: Journey Forward
Abstract Views :191 |
PDF Views:81
Authors
Affiliations
1 Department of Onco-Anaesthesiology and Palliative Medicine, Dr BRAIRCH, All India Institute of Medical Sciences, New Delhi, IN
2 Department of Anaesthesiology, Jawahar Lal Nehru Medical College, Aligarh Muslim University, Uttar Pradesh, 202001, IN
3 Anaesthesiology, Max Smart Superspeciality Hospital, Saket, Delhi, IN
4 Indian Society of Anesthesiologists, IN
5 Indian Resuscitation Council, IN
1 Department of Onco-Anaesthesiology and Palliative Medicine, Dr BRAIRCH, All India Institute of Medical Sciences, New Delhi, IN
2 Department of Anaesthesiology, Jawahar Lal Nehru Medical College, Aligarh Muslim University, Uttar Pradesh, 202001, IN
3 Anaesthesiology, Max Smart Superspeciality Hospital, Saket, Delhi, IN
4 Indian Society of Anesthesiologists, IN
5 Indian Resuscitation Council, IN
Source
Central Journal of ISA, Vol 2, No 1 (2018), Pagination: 1-2Abstract
No Abstract.Keywords
No KeywordsReferences
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