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A B C D E F G H I J K L M N O P Q R S T U V W X Y Z All
Natarajan, K.
- Antibacterial Activity of Crude Extracts of Marine Invertebrate Polyclinum madrasensis Sebastian
Abstract Views :420 |
PDF Views:136
Authors
Affiliations
1 Dept. of Pharmaceutical Biotechnology, Ultra College of Pharmacy, 4/235, Thasildhar nagar, Madurai-625020, IN
2 Dept. of Pharmacology, Ultra College of Pharmacy, Madurai-625020, IN
3 Dept. of Pharmaceutics, Ultra College of Pharmacy, Madurai-625020, IN
4 1Dept. of Pharmaceutical Biotechnology, Ultra College of Pharmacy, 4/235, Thasildhar nagar, Madurai-625020, IN
1 Dept. of Pharmaceutical Biotechnology, Ultra College of Pharmacy, 4/235, Thasildhar nagar, Madurai-625020, IN
2 Dept. of Pharmacology, Ultra College of Pharmacy, Madurai-625020, IN
3 Dept. of Pharmaceutics, Ultra College of Pharmacy, Madurai-625020, IN
4 1Dept. of Pharmaceutical Biotechnology, Ultra College of Pharmacy, 4/235, Thasildhar nagar, Madurai-625020, IN
Source
Indian Journal of Science and Technology, Vol 3, No 3 (2010), Pagination: 303-304Abstract
Antibacterial activity of methanol, hexane and petroleum ether extracts of Polyclinum madrasensis was evaluated by cup plate method against various clinical isolates. Two different concentrations (1&4 mg/ml) were analyzed. Methanolic extract of P. madrasensis demonstrated high degree of activity against all tested bacterial isolates in increasing concentrations, whereas hexane extract showed good activity against gram negative pathogens in high concentration and moderate against gram positive pathogens in lower concentration. All strains were resistant to Pet ether extract in both the concentrations when compared to the standard (ciprofloxacin) used. The MIC and MBC for methanolic extract tested in study inferred that the values range between 0.70-0.95 mg/ml and 0.85-1.1 mg/ml respectively. It was concluded from the study that methanolic extract of P. madrasensis exhibits potential antibacterial property.Keywords
Antimicrobial Activity, Polyclinum Madrasensis, Cup Plate Method, Clinical IsolatesFull Text
References
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- Seleghim MHR, Lira SP, Kossuga MH, Batista T, Berlinck RGS and Hajdu E (2007) Antibiotic, cytotoxic and enzyme inhibitory activity of crude extracts from Brazilian marine invertebrates. Brazilian J. Pharmacognosy. 17(3), 287-318.
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- GC-MS Analysis of Biologically Active Compounds in Indigofera viscosa Lam.
Abstract Views :250 |
PDF Views:0
Authors
Affiliations
1 Dr. Zahir Husain College, Ilayankudi, T.N., IN
2 Department of Botany, Rani Anna Govt. College for Women, Tirunelveli, T.N., IN
3 Siddha Medicinal Plants Garden, C.C.R.S., Mettur Dam, T.N., IN
4 Nnai Arts and Science College for Women, Karur, T.N., IN
1 Dr. Zahir Husain College, Ilayankudi, T.N., IN
2 Department of Botany, Rani Anna Govt. College for Women, Tirunelveli, T.N., IN
3 Siddha Medicinal Plants Garden, C.C.R.S., Mettur Dam, T.N., IN
4 Nnai Arts and Science College for Women, Karur, T.N., IN
Source
International Journal of Plant Sciences, Vol 8, No 1 (2013), Pagination: 116-119Abstract
A medicinal herb can be viewed as a synthetic laboratory as it produces and contains a number of chemical compounds. Gas chromatography (GC) and mass spectroscopy (MS) can be used to study traditional medicines and characterize the compound of interest. Indigofera viscosa Lam. is herb distributed in hill slopes of southern peninsular India. The macerate of the crushed whole plant is used as rectal application, twice a week for one week, to stop diarrhea. Sterols, triterpenes, polar and other constituents in whole plant of Indigofera viscosa Lam. were analyzed by gas chromatography-mass spectrometry. Over 23 compounds were identified. Sitosterol and stigmasterol were the most abundant of sterols identified in the sterol fraction.Keywords
Gas Chromatography (gc), Mass Spectroscopy (ms), Indigofera Viscosa
- Antidiabetic Activity of Swietenia mahagoni Seed Powder in Alloxan Induced Diabetic Mice
Abstract Views :816 |
PDF Views:0
Authors
Affiliations
1 Department of Pharmacology, Ultra College of Pharmacy, Madurai, IN
2 Department of Pharmaceutical Biotechnology, Ultra College of Pharmacy, Madurai, IN
3 Department of Pharmacology, Madurai Medical College, Madurai, IN
1 Department of Pharmacology, Ultra College of Pharmacy, Madurai, IN
2 Department of Pharmaceutical Biotechnology, Ultra College of Pharmacy, Madurai, IN
3 Department of Pharmacology, Madurai Medical College, Madurai, IN
Source
Research Journal of Pharmacology and Pharmacodynamics, Vol 2, No 4 (2010), Pagination: 296-299Abstract
Swietenia mahagoni (Meliaceae) is an evergreen hard wood timber species widely distributed in India and has ethno medicinal uses in malaria, diabetes, anemia, diarrhoea, fever, and dysentery. In this present study antidiabetic effect of Swietenia mahagoni seeds were evaluated in alloxan induced diabetic mice. Blood and urine Glucose levels, food and water consumptions and histopathological studies were determined. In diabetic mice, Swietenia mahagoni seeds significantly reduced the elevated blood glucose level by 43.92% at 500mg/kg and 42.47% at 250mg/kg compared to vehicle treated diabetic mice, without increase in urine glucose, food and water intake. The experimental data indicated that Swietenia mahagoni demonstrated significant antidiabetic action in alloxan induced diabetic mice and could be a potential orally active drug for diabetes mellitus.Keywords
Antidiabetic, Indian Mahogany, Alloxan, Diabetic Mice, Swietenia.References
- Amit R, Shailendra S. Limonoids. Overview of significant bioactive triterpenes distributed in plants kingdom. Bio Pharm Bull 2006; 29: 191-201.
- Abdelgaleil SAM et al. D-seco limonoids from the leaves of Swietenia mahogany. Phytochemistry. 2006; 67: 452-458.
- Tripathy.K.D, Essential of medicinal pharmacology. Jaypee brother's Medical Publishers (P) Ltd, New Delhi, 2003; 5th ed , pp. 235-253.
- Badole S et al. Antihyperglycemic activity of aqueous extract of leaves of Cocculus hirsutus (L.) Diels in Alloxan - induced diabetic mice. Ind J pharmacol. 2006; 38: 49-53.
- Srinivasan K, Ramarao P. Animal models in type 2 diabetes research, an overview. Ind. J Med Res 2007; 125: 451-472.
- Bacsal K et al. The effect of Swietenia mahogani (mahogany) seed extract on indomethacin-induced gastric ulcers in female Sprague-Dawley rats. Acta Medica Philippina. 1997; 33: 127-139.
- Elliott JJ, Dewchand H and Altmann DM. Streptozotocin-induced diabetes in mice lacking α,β,T cells. Clin Exp immunology. 1997; 109: 116-120.
- Antia BS, Okokon JE and Okon PA. Hypoglycemic activity of aqueous leaf extract of Persea americana Mill. Ind J pharmacol. 2005; 37(5): 325-326.
- Gorray KC et al. Baskin, D, Brodsky J, Fujimoto WY. Responses of pancreatic β cells to alloxan and streptozotocin in the guinea pig. Pancreas. 1986; 1: 130-138.
- Ghosh S, Suryawanshi SA. Effect of Vinca rosea extracts in treatment of alloxan diabetes in male albino rats. Ind. J. Exp. Biol. 2001; 39: 748-759.
- Natural Enemies of Bemisia tabaci Gennadius and Effect of Insecticides on their Activity
Abstract Views :212 |
PDF Views:204
Authors
Affiliations
1 Central Institute for Cotton Research, Regional Station, Coimbatore-641 003, IN
1 Central Institute for Cotton Research, Regional Station, Coimbatore-641 003, IN
Source
Journal of Biological Control, Vol 4, No 2 (1990), Pagination: 86-88Abstract
In a survey on the natural enemies of Bemlsia tabaci Gennadius, two parasitoids Eretmocerus mundus Mere and Encarsia shafeel (Hayat) and seven predators were recorded in cotton ecosystem. The predators viz., Serangium parcesetosum (Coccinellidae), Deraeocoris indianus (Miridae) and Paederus fuscipes Curtis (Staphylinidae) were recorded for the first time on this pest. Field experiment revealed that the activity and abundance of the natural enemies were significantly reduced when triazophos, monocrotophos and methamidophos were sprayed as compared to endosuifan and phosalone, Neem oil and fish oil rosin soap were less harmful to the natural enemies.Keywords
Bemisia tabaci, Natural Enemies, Toxicity Insecticides.Full Text
- Effect of Leaf Pubescence in Cotton, Gossypium hirsutum on the Parasitism of Whitefly, Bemisia tabaci (Gennadius)
Abstract Views :216 |
PDF Views:130
Authors
Affiliations
1 Central Institute for Cotton Research, Regional Station, Coimbatore-641 003, IN
1 Central Institute for Cotton Research, Regional Station, Coimbatore-641 003, IN
Source
Journal of Biological Control, Vol 4, No 1 (1990), Pagination: 57-58Abstract
Two aphelinid parasites viz., Eretmocerus mundus Mercet and Encarsia shafeei Hayat are important parasitoids causing 85 to 90% mortality of cotton whitefly, Bemisia tabaci (Gennadius) (Natarajan et al., 1986.) The abundance and activity of natural enemies depend on the physical and chemical traits of the host plant upon which the host insect or prey is located (Vinson, 1976). In cotton, cultivars with glabrous leaf support more natural enemies than those with hairy leaves (Schuster and Calderon, 1986). The effect of cotton genotypes on the activity of two parasites of B. tabaci is reported.Keywords
Cotton, Leaf Pubescense, Whitefly, Parasitism.Full Text
- An Easy Method for Clipping Regular/Irregular 2D Polygon
Abstract Views :170 |
PDF Views:2
Authors
K. Natarajan
1,
K. Kuppusamy
2
Affiliations
1 Department of Computer Science, Thiagarajar College, Madurai-625009, TN, IN
2 Department of Computer Science and Engineering, Alagappa University, Karaikudi, TN, IN
1 Department of Computer Science, Thiagarajar College, Madurai-625009, TN, IN
2 Department of Computer Science and Engineering, Alagappa University, Karaikudi, TN, IN
Source
Digital Image Processing, Vol 3, No 9 (2011), Pagination: 519-523Abstract
The paper presents a new simple clipping algorithm for 2D-polygon against rectangular windows. The polygon clipping process often involves a lot of intersection calculations and comparison. This paper propose a new 2D polygon clipping method, which makes only least number of edge and clipping region comparison and very few intersection calculations than any other traditional polygon clipping algorithms. The proposed algorithm is explained in step by step and compared with the Patrick-Gilles Maillot proposed method, and the Sutherland-Hodgeman algorithm and showing very less edge and clipping region comparison. The experimental results strongly support superiority of the proposed algorithm in comparison wise and it is theoretically and experimentally better than the conventional and Patrick-Gilles Maillot proposed method.Keywords
Clipping Region, Clipped Point, Gentle Slope, Polygon Clipping, Sharp Slope.- A New Fast Clipping Algorithm for 2D-Polygon against Rectangular Windows
Abstract Views :181 |
PDF Views:32
Authors
K. Natarajan
1,
K. Kuppusamy
2
Affiliations
1 Department of Computer Science, Thiagarajar College, Madurai – 625 009, TN, IN
2 Department of Computer Science and Engineering, Alagappa University, Karaikudi, TN, IN
1 Department of Computer Science, Thiagarajar College, Madurai – 625 009, TN, IN
2 Department of Computer Science and Engineering, Alagappa University, Karaikudi, TN, IN
Source
Digital Image Processing, Vol 3, No 1 (2011), Pagination: 63-67Abstract
Polygon clipping process often involves a lot of intersection calculations and comparison. One way for improving the efficiency of a polygon clipping algorithm is to save the unnecessary intersection calculations demanded by traditional algorithm by rejecting totally the edges lies outside the window. This paper presents a new 2D polygon clipping method, based on an extension to the Sutherland- Hodgman polygon clipping method in which the efficiency is improved either by rejecting the edges lies outside a boundary or by avoiding the comparison of clipping boundaries against the sides of a polygon which neither totally nor partially crossing a polygon. The proposed algorithm neither remembers so-called entry/exit intersection points and nor about union points. After discussing two basic polygon clipping algorithms, a different approach is proposed, explaining the principles of a new algorithm and presenting it step by step. An example implementation of the algorithm is given along with some results. A comparison between the proposed method, the Patrick-Gilles Maillot polygon clipping algorithm, and the Sutherland-Hodgman algorithm is also given, showing very less comparison of edge and clipping region boundary than the Sutherland-Hodgman algorithm, and the Patrick-Gilles Maillot proposed method.Keywords
Clipping Region, Line Intersection, Polygon Clipping, Window.- An Enhanced Method for Filling a 2D-Polygon
Abstract Views :160 |
PDF Views:2
Authors
K. Natarajan
1,
K. Kuppusamy
2
Affiliations
1 Department of Computer Science in Thiagarajar College, Madurai, IN
2 Department of Computer Science and Engineering in Alagappa University, Karaikudi, IN
1 Department of Computer Science in Thiagarajar College, Madurai, IN
2 Department of Computer Science and Engineering in Alagappa University, Karaikudi, IN
Source
Digital Image Processing, Vol 2, No 11 (2010), Pagination: 486-489Abstract
Polygon filling is a fundamental operation in computer graphics and image processing. The conventional polygon filling algorithms normally adopt an approach of scan line at a time generally called Scan_Line Algorithms typically uses many procedures and data structure of table (records) and fields. Using these procedures and data structures, the polygon filling process slows down because, many procedures which are involving to fill a polygon performing operation of sorting, reordering records and fields in a table and it makes these algorithm a time-consuming, tedious and very complex. This paper presents an enhanced 2D polygon filling method based on to the Scan-Line algorithm. After discussing simply about the Scan-Line filling algorithm and its procedures, a different approach is proposed and is explained step by step.
This proposed method, KN algorithm is fast, and uses simple data structure and less execution time, data reordering work and is independent of the polygon geometry. The experimental results strongly support superiority of the proposed algorithm in execution time wise and it is theoretically and experimentally better than the conventional algorithm.Keywords
Concave Polygon, End Points, Polygon Filling, Vertex.- A New Method for Filling a 2D-Polygon
Abstract Views :168 |
PDF Views:1
Authors
K. Natarajan
1,
K. Kuppusamy
2
Affiliations
1 Department of Computer Science in Thiagarajar College, Madurai, IN
2 Department of Computer Science and Engineering in Alagappa University, Karaikudi, IN
1 Department of Computer Science in Thiagarajar College, Madurai, IN
2 Department of Computer Science and Engineering in Alagappa University, Karaikudi, IN
Source
Digital Image Processing, Vol 2, No 11 (2010), Pagination: 490-495Abstract
Polygon filling process often involves with lot of procedures which are repeatedly called by one another and making lot of calculations and data reordering works to fill a polygon. One way for improving the efficiency of a polygon filling algorithm is to save the unnecessary calculations and reordering works demanded by traditional algorithms either for rejecting some reordering works or for avoiding some sorting and calculations works. An adaptive filling algorithm is presented here to achieve this goal. The filling process of our new algorithm, NH algorithm, consists of five steps. Firstly, we read the value of edges of a polygon and avoiding the sorting of the sides which are normally required in a traditional algorithm. Secondly, we calculated all boundary points for each sides of a polygon between its maximum and minimum y value. Thirdly, we find all boundary points for each scan level. Fourthly, we sort all boundary points in the order of their minimum x values. And finally, even number of boundary points are selected and filled. Here, the data reordering analysis and experimental statistics between these two algorithms demonstrate the high efficiency of our new algorithm.
Keywords
Boundary Points, Concave Polygon, Polygon Filling, Vertex.- Influence of SiC and Al2O3 Particulate Reinforcements on Metal-Metal Wear Behavior of Al6061 Alloy Hybrid Composites Produced by Stir Casting Method
Abstract Views :175 |
PDF Views:4
Authors
Affiliations
1 School of Mechanical Engineering, Vel Tech Dr.RR & Dr.SR Technical University, Chennai-600062, Tamilnadu, IN
2 Department of Mechanical Engineering, Sri Sai Ram Institute of Technology, Chennai-600044, Tamilnadu, IN
1 School of Mechanical Engineering, Vel Tech Dr.RR & Dr.SR Technical University, Chennai-600062, Tamilnadu, IN
2 Department of Mechanical Engineering, Sri Sai Ram Institute of Technology, Chennai-600044, Tamilnadu, IN
Source
Artificial Intelligent Systems and Machine Learning, Vol 2, No 3 (2010), Pagination:Abstract
Dry sliding metal-metal wear behavior of Al6061 alloy, discontinuously reinforced with fine particles of SiC and Al2O3 are presented and discussed this paper. The discontinuously reinforced aluminum (DRA) alloy composites with 5-25% volume fractions of SiC and Al2O3 particulates were produced by stir casting method and using them test specimens were prepared. The dry sliding behavior of these hybrid composite specimens and that of Al6061 unreinforced alloy at room temperature was investigated by using pin-on-disk wear testing machine over a load range of 29.43N-49.05N (3-5 kgf) for a total sliding distance of 1413m at a constant sliding speed of 1.57m/s. The results show that, the reinforcement of the metal matrix with SiC and Al2O3 particulates upto a volume fraction of 25% reduces the wear rate at room temperature. Higher the volume fraction of the reinforcements lower was the rate of wear. The results also show that the wear of test specimens increase with increasing load and sliding distance. Also micro hardness of the specimens at the room temperature was measured before and after the wear tests by Vickers hardness testing machine. The micro hardness of the hybrid composite test specimens increases with increasing volume fraction of particulates reinforcement. The optical micrographs taken for the micro structure analysis of the hybrid composite specimens show that the SiC and Al2O3 particulates are uniformly distributed in the matrix. It was also found from the optical micrographs that the porosity of the test specimens increases with the increasing volume fraction of particulate reinforcement. The wear surfaces were examined by scanning electron microscopy, which showed that the wear surface of the composite alloy was generally much rougher than that of the unreinforced alloy. Large grooved regions and cavities with ceramic particles were found on the worn surface of the composite alloy. This indicates an abrasive wear mechanism which is essentially a result of hard ceramic particles exposed on the worn surface.Keywords
Al6061Alloys Hybrid Composites, Stir Casting, Wear Behavior of Composites.- In Vitro Cytotoxic Study on Crude Extract of Marine Invertebrate Animal Polyclinum madrasensis Sebastian
Abstract Views :178 |
PDF Views:2
Authors
Affiliations
1 Department of Pharmaceutical Biotechnology, Ultra College of Pharmacy, Madurai, IN
1 Department of Pharmaceutical Biotechnology, Ultra College of Pharmacy, Madurai, IN
Source
Asian Journal of Pharmacy and Technology, Vol 1, No 4 (2011), Pagination: 152-154Abstract
Many marine origin organic molecules entered clinical studies for anticancer therapy. Ascidians, a marine invertebrate animal draw attention of the researchers for its versatility as medicine and nutrition. In this study methylene chloride crude extract of Polyclinum madrasensis Sebastian (Ascidaciae) was tested for its in-vitro anticancer property on HeLa cell lines (cervical cancer cell lines) using MTT assay. Results revealed that the extract exhibits cytotoxic effect on the cell lines used (IC 50- 0.23mg/ml). Extract was further elucidated using chemical and spectral analysis (IR, HNMR), in which peptides were found to be the major constituent. As a conclusion, Polyclinum madrasensis is found to be a good source for drug lead component in cancer drug discovery process.Keywords
Polyclinum madrasensis, PME, Cytotoxicity, HeLa.- Study on Tri Calcium Phosphate Solubilisation Efficiency of Soil Microbes
Abstract Views :150 |
PDF Views:0
Authors
Affiliations
1 Ultra College of Pharmacy, Madurai, IN
1 Ultra College of Pharmacy, Madurai, IN
Source
Asian Journal of Research in Chemistry, Vol 3, No 4 (2010), Pagination: 1054-1057Abstract
Different soil microbes were analyzed for their phosphate solubilizing capacity. The characterization of the microbes which exhibits phosphate solubilisation in preliminary screening reveals that the isolated strains were Pseudomonas aeroginosa, Pseudomonas flurosence, Bacillus subtilis, Bacillus cereus and E. coli. General parameters for determining phosphate solubilisation in PVK broth such as pH changes, estimation of phosphorus release in media and the phosphatase enzyme activity were performed. Investigation results showed high potency of the microbes to solubilize TCP. From the above tested organisms Pseudomonos pocess high efficiency to solubilize TCP followed by Bacillus and E.coli on tested all parameters. Biofertilizer was developed and nursery experiments were conducted with paddy crop. Parameters such as Germination of seed, Color of the crop and Height were analyzed. Biofertilizer treated crop displayed comparatively good results with non treated and chemical fertilizer treated crop. In conclusion Pseudomonas and Bacillus strains showed good phosphate solubilisation and can be utilized in biofertilizers.Keywords
Phosphate Solubilization, PVK Broth, Pseudomonas, Bacillus.- Hepatoprotective and Anti Pyretic Activities of Methanolic Extract of Butea monosperma Lam Stem Bark in Wister Rats
Abstract Views :172 |
PDF Views:1
Authors
Affiliations
1 Department of Pharmacology, Ultra College of Pharmacy, Madurai, IN
1 Department of Pharmacology, Ultra College of Pharmacy, Madurai, IN