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M. Gayathri , K. Kannabiran

Abstract

A study was planned to evaluate the ameliorative potential of aqueous extract of bark of Pterocarpus marsupium Roxb (PM) in streptozotocin (STZ) induced diabetic rats. The effect of oral administration of plant extract on serum electrolytes, serum glycolytic enzymes, liver microsomal protein, hepatic cytochrome P-450 dependent monooxygenase enzymes and lipid peroxidation of the liver and kidney of streptozoticin - induced diabetic rats was studied. Administration of the bark extract to diabetic rats restored the levels of serum electrolytes, glycolytic enzymes and hepatic cytochrome P-450 dependent enzyme systems by preventing the formation of liver and kidney lipid peroxides at the end of study period of 12 weeks. Further, the bark extract at the dosage of 500mg/kg/ day exhibits a significant ameliorative activity as evidenced by the histological studies in normal and PM treated STZ - induced diabetic rats. On the basis of our findings, it could be used as an effective ameliorative agent for the management of diabetes and associated metabolic alterations.

Keywords

Pterocarpus marsupium Roxb, Ameliorative Potential, Cytochrome P-450 Dependent Enzymes, Lipid Peroxides

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Lakshmipathy Deepika , K. Kannabiran

Abstract

Actinobacteria isolated from soil samples collected at the Ennore saltern, Tamil Nadu was screened for antibacterial and antifungal activity against common clinical pathogens. The isolate VITDDK3 exhibited more promising antagonistic activity against Escherichia coli, Pseudomonas aeruginosa, Aspergillus flavus and Aspergillus fumigatus. Presence of LL-Diaminopimelic acid and glycine assigned the isolate VITDDK3 to the genus Streptomyces. Further 16S rRNA partial gene sequence was carried out to confirm the chemotaxonomic results. BLAST analysis showed that the strain VITDDK3 possessed 98% similarity with Streptomyces sp. A254Ydz-ZZ but phylogenetic analysis revealed that its closest neighbour was Streptomyces tricolor HBUM175176. The rRNA secondary structure and the restriction sites of VITDDK3 were predicted using Genebee and NEBCutter online softwares respectively.

Keywords

Streptomyces sp. VITDDK3, Antibacterial Activity, Antifungal Activity, Chemotaxonomy, Phylogenetic Analysis.

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K. Kannabiran ¹, Padmanaban ¹

Affiliations
1 Department of Spices and Plantation Crops, Horticulture College & Research Institute, TNAU, Coimbatore, Tamil Nadu, IN

Abstract

The experiment studying the effect of growth regulators in Glory lily was conducted in Factorial Randomized Block Design with two factors. Five different growth regulators, namely, GA₃, CCC, MH, Ethrel and NAA, each at two concentrations (250ppm and 500ppm) were  applied on tubers of two different sizes (average weight of 90-100 g and 140-150 g tubers). Among the various treatments experimented, the growth attributing characters like plant height and number of branches showed positive response to the growth promoter, GA₃ @ 500 ppm applied on to tubers with an average weight of 140-150 g (GR₃W₂). This combination exerted significant influence on the above mentioned traits in Glory lily.

Keywords

Glory Lily, Medicinal Plant, Growth Regulators.

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