Informatics Publishing Limited

R. S. Dass ¹, Jai Kishan ¹, U. B. Singh ¹

Affiliations
1 Nuclear Research Laboratory, Animal Nutrition Division, Indian Veterinary Research Institute, Izatnagar - 243122 (U. P.), IN

Abstract

In India the crop residues from the staple feed for the livestock and are a potential source of energy for the ruminants. Unfortunately their usefulness is limited due to low digestibility and low crude protein content. Treatment with different chemicals have been used to increase their digestibility. Recently the use of ammonia (produced from urea) for the treatment of pool quality roughages has been tried.

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Abhishek Chauhan ¹, Jai Kishan ², Sameer Singhal ³, Achchhar Singh ⁴, Aditi Gupta ⁵, Pankaj Saini ¹

Affiliations
1 Junior Resident, Department of Respiratory Medicine, MMIMSR, M.M. Deemed to be University, Mullana, Ambala, Haryana, IN
2 Prof and Head, Department of Respiratory Medicine, MMIMSR, M.M. Deemed to be University, Mullana, Ambala, Haryana, IN
3 Professor, Department of Respiratory Medicine, MMIMSR, M.M. Deemed to be University, Mullana, Ambala, Haryana, IN
4 Associate Professor, Department of Respiratory Medicine, MMIMSR, M.M. Deemed to be University, Mullana, Ambala, Haryana, IN
5 Assistant Professor, Department of Respiratory Medicine, MMIMSR, M.M. Deemed to be University, Mullana, Ambala, Haryana, IN

Abstract

Tuberculosis is an infectious disease. It is caused by bacteria Mycobacterium Tuberculosis. It can be diagnosed by demonstrating AFB by either phenotypic method like sputum smear microscopy, culture or by genotypic method like NAAT or LPA. For better results there should be a good quality sputum sample. Induction of sputum is a method for improving the quality of sample. The most commonly used method is induction using 3% saline. It has been seen that during taking throat swab specimen patients usually produce cough. This induced cough can produce better quality of sputum. The following study was done to know about the role of throat swab as a method of sputum induction.

Keywords

AFB, CBNAAT, LPA, Mycobacterium Tuberculosis.

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Achchhar Singh ¹, Jai Kishan ², Sameer Singhal ³, Vishvdeep Saini ⁴, Abhishek Chauhan ⁴

Affiliations
1 Associate Professor, Department of Respiratory Medicine, MMIMSR, M.M. Deemed to be University, Mullana, Ambala, Haryana, IN
2 Professor and Head, Department of Respiratory Medicine, MMIMSR, M.M. Deemed to be University, Mullana, Ambala, Haryana, IN
3 Professor, Department of Respiratory Medicine, MMIMSR, M.M. Deemed to be University, Mullana, Ambala, Haryana, IN
4 Junior Resident, Department of Respiratory Medicine, MMIMSR, M.M. Deemed to be University, Mullana, Ambala, Haryana, IN

Abstract

The aim was to evaluate the inhalation technique among COPD patients using pressurized metered dose inhaler and determinants of incorrect inhalation technique. In this hospital based cross-sectional study, total 92 COPD patients were enrolled. Basic socio-demographic information was collected. The inhalation technique was visually observed and scored on checklist. Statistical Analysis Used: Chi-square test and Fisher exact test. Among the 92 patients observed, 69 (75.0%) were males. The mean age of the patients was 45.8 ± 1.4 years. Correct technique was observed in only 22 (23.9%) patients step at which maximum number of patients committed mistake was exhalation 65.2% followed by breath holding 45.7% and multiple actuations were seen in 44.5%. It was found that substantial errors were made in the inhalation technique hence proper training and follow-up of the patients is required to achieve the desired effects of the inhaled medications.

Keywords

COPD, pMDI, Inhalation technique.

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Jai Kishan ¹, Obul Reddy ², Achchhar Singh ³, Sameer Singhal ⁴

Affiliations
1 Professor and Head, Department of Respiratory Medicine, MMIMSR, M.M. Deemed to be University, Mullana, Ambala, Haryana
2 Junior Resident, Department of Respiratory Medicine, MMIMSR, M.M. Deemed to be University, Mullana, Ambala, Haryana, IN
3 Associate Professor, Department of Respiratory Medicine, MMIMSR, M.M. Deemed to be University, Mullana, Ambala, Haryana, IN
4 Professor, Department of Respiratory Medicine, MMIMSR, M.M. Deemed to be University, Mullana, Ambala, Haryana, IN

Abstract

Background: Pulse oximetry is widely used in patients of respiratory diseases for monitoring the oxygen saturation in blood. First commercial pulse oximetry was used in 1975. Although there have been many improvements in its design since then, still there are a few limitations. The limitations of pulse oximetry include mechanical artefacts accuracy, electromagnetic interference, calibration, delay, pulse dependencevolume and rhythm, abnormal haemoglobins, other absorbents, pulsatile veins, pigmentation. Objective: Despite so many studies on the pulse oximetry, there still isn’t any study on pulse oximetry which focused changes in the readings of pulse oximeter with respect to position of finger in relation to the sensor. So in this study we tried to analyse the effect of anatomical plane of finger on O₂ saturation as measured by pulse oximetry. Material and Method: This study was done on 400 patients and included both healthy and unhealthy patients. Portable pulse oximeter was used in the study. Pulse oximetry was done on the subjects with finger in supine, prone and lateral position in respect to the probe, while the patient was in sitting position with a waiting period of 1 min between each reading. Results: The study shows no significant difference (p value > 0.05) between Spo₂ value obtained from any position of finger in relation to the sensor while applying the pulse oximeter. Conclusion: Pulse oximetry is a very safe, non-invasive and inexpensive way of continuous O₂ saturation monitoring in critical patients. Mal-positioning of sensors can be potentially dangerous as it may give erroneous high or low readings. The ways to prevent mal-positioning of the sensor are good design of pulse oximeter and ensuring that it is properly visible to the clinician.

Keywords

Pulse oximetry, oxygen saturation variation, sensor mal-positioning.

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Vishvdeep Saini ¹, Jai Kishan ², Sameer Singhal ³, Sukhjinder Pal Singh ⁴, Achchhar Singh ⁵

Affiliations
1 Junior Resident, Department of Respiratory Medicine, MMIMSR, M.M. Deemed to be University, Mullana, Ambala, Haryana, IN
2 Professor and Head, Department of Respiratory Medicine, MMIMSR, M.M. Deemed to be University, Mullana, Ambala, Haryana, IN
3 Professor, Department of Respiratory Medicine, MMIMSR, M.M. Deemed to be University, Mullana, Ambala, Haryana, IN
4 Senior Resident, Department of Respiratory Medicine, MMMC & H, Kumarhatti, Solan, Himachal Pradesh, IN
5 Associate Professor, Department of Respiratory Medicine, MMIMSR, M.M. Deemed to be University, Mullana, Ambala, Haryana, IN

Abstract

Introduction: CBNAAT is a very useful rapid diagnostic test for the early diagnosis of DS and DR TB. Report of sample can be available in just 2 hours. But the results of these tests are not available for many days to weeks which results in delay in diagnosis and treatment initiation. Material and Method: This study was conducted for a period of 4 months from mid-April to mid-august 2018 in MMIMSR, Mullana. A total of 535 samples were sent for CBNAAT to TB Hospital, Ambala and the time taken from sending of samples to the receiving of report was analysed and time lag was calculated. Results: Out of 535 samples, 429 samples were negative, 104 were positive for MTB and 2 samples resulted as invalid/error. Out of 104 positive samples, 95 were rifampicin sensitive and 9 were rifampicin resistant MTB. The average time lag in reporting of CBNAAT samples was 11.1 days with shortest time being 2 days and longest being 33 days. Conclusion: CBNAAT is a very useful modality in TB diagnosis and should be made available to all eligible patients especially so in high DR-TB prevalence areas. But delay in reporting undermines the purpose of the test i.e. rapid diagnosis and treatment. There is an urgent need to establish more centres with CBNAAT facility throughout India so that there is no delay in reporting and early treatment can be started.

Keywords

RNTCP, CBNAAT, Tuberculosis, NIKSHAY, TB prevalence.

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Ajit Yadav ¹, Jai Kishan ², Sameer Singhal ³, Achchhar Singh ⁴, Aditi Gupta ⁵

Affiliations
1 Junior Resident,Department of Respiratory Medicine, MMIMSR, M.M. Deemed to be University, Mullana, Ambala, Haryana, IN
2 Prof and Head, Department of Respiratory Medicine, MMIMSR, M.M. Deemed to be University, Mullana, Ambala, Haryana, IN
3 Professor, Department of Respiratory Medicine, MMIMSR, M.M. Deemed to be University, Mullana, Ambala, Haryana, IN
4 Associate Professor, Department of Respiratory Medicine, MMIMSR, M.M. Deemed to be University, Mullana, Ambala, Haryana, IN
5 Assistant Professor, Department of Respiratory Medicine, MMIMSR, M.M. Deemed to be University, Mullana, Ambala, Haryana, IN

Abstract

Aim: To study the prevalence of obstructive airway disease in patient of OSA diagnosed by polysomnography. Method: This study is a descriptive cross-sectional and was carried out in patients admitted in the department of Respiratory Medicine who were diagnosed with OSA after polysomnography. Total 41 patients who were diagnosed as cases of obstructive sleep apnea were clinically evaluated and investigated by history taking and final diagnosis were made as either COPD, Asthma on basis of GOLD and GINA guidelines respectively. Results: Mean age of the study participants was 50.95 years. Prevalence of Asthma and COPD among cases with OSA was 58.5% and 14.6%.Mean AHI and ESS score was 42.45 and 16.80 respectively. The most common co-morbid condition was GERD (19.5%). Conclusion: Present study concluded that asthma is more prevalent than COPD in patients of obstructive sleep apnea. The main factors associated with Obstructive lung diseases and its pathogenesis is the obesity, hypertension, smoking habits, adenoids, tonsillitis, musculoskeletal changes, weakness and atrophy of muscles of upper respiratory tract.

Keywords

Asthma, COPD, Obstructive Sleep Apnea, Polysomnography

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Abhishek Chauhan ¹, Jai Kishan ², Sameer Singhal ³, Achhar Singh ⁴, Aditi Gupta ⁵

Affiliations
1 Resident, Department of Respiratory Medicine, M.M. (Deemed to be) University, Mullana, Ambala, IN
2 Prof. and Head, Department of Respiratory Medicine, M.M. (Deemed to be) University, Mullana, Ambala, IN
3 Professor, Department of Respiratory Medicine, M.M. (Deemed to be) University, Mullana, Ambala, IN
4 Associate Professor, Department of Respiratory Medicine, M.M. (Deemed to be) University, Mullana, Ambala, IN
5 Assistant Professor, Department of Respiratory Medicine, M.M. (Deemed to be) University, Mullana, Ambala, IN

Abstract

Sputum examination is the most widely used test for diagnosis of TB. Under RNTCP two samples of sputum are required for examinations which are preferably 1st spot and early morning sample or two spot samples collected on the same day. Patients usually come from far off places at the tertiary care centre and frequent visits are usually not possible. Giving an early morning sample is usually defaulted by the patient due to various reasons. The present study was aimed at studying the delay in giving the early morning sample and barriers in accessing the sputum smear microscopy services at a tertiary care hospital. In this study 300 presumptive TB patients were studied. Patients were asked to give a 1st spot sample for sputum smear examination and asked to bring early morning sputum sample. Patients who refused to give early morning sample were asked to give 2nd spot sample and the reason for not coming early morning were noted. The patients who did not come despite agreeing to come were noted. If they came after a delay of few days, then also the reason of delay were noted. It was found that nearly one third (31%) of the patients agreed and came on the next day to give early morning sample. A large number of patients (16%) did not come at all to give the early morning sample.

Keywords

Pulmonary tuberculosis, presumptive TB patient, sputum microscopy, spot sample, early morning sample, RNTCP.

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Ajit Yadav ¹, Jai Kishan ², Sameer Singhal ³, Achchhar Singh ⁴, Aditi Gupta ⁴

Affiliations
1 Junior Resident, Department of Respiratory Medicine, MMIMSR, M.M. Deemed to be University, Mullana, Ambala, Haryana, IN
2 Prof. and Head, Department of Respiratory Medicine, MMIMSR, M.M. Deemed to be University, Mullana, Ambala, Haryana, IN
3 Professor, Department of Respiratory Medicine, MMIMSR, M.M. Deemed to be University, Mullana, Ambala, Haryana, IN
4 Associate Professor, Department of Respiratory Medicine, MMIMSR, M.M. Deemed to be University, Mullana, Ambala, Haryana, IN

Abstract

Cough as symptom to diagnose achalasia cardia. Achalasia typically presents with dysphagia and regurgitation of undigested food. Diagnosis is usually performed with esophageal manometry, barium swallow before macroscopic anatomical changes appear. But sometime cough as a symptom can diagnose. We present a 45-year old women whose diagnosis was suspected with chest-x-ray showing enlargement of right mediastinum. Diagnosis was then confirmed with upper endoscopy and barium swallow.

Keywords

Cough, Dyspnoe Achalasia; Dysphagia; Barium swallow; Heller myotomy; Pneumatic dilatation.

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Achchhar Singh ¹, Jai Kishan ², Sameer Singhal ³, Vishvdeep Saini ⁴, Abhishek Chauhan ⁴

Affiliations
1 Associate Professor, Department of Respiratory Medicine, MMIMSR, M.M. Deemed to be University, Mullana, Ambala, Haryana, IN
2 Professor and Head, Department of Respiratory Medicine, MMIMSR, M.M. Deemed to be University, Mullana, Ambala, Haryana, IN
3 Professor, Department of Respiratory Medicine, MMIMSR, M.M. Deemed to be University, Mullana, Ambala, Haryana, IN
4 Junior Resident, Department of Respiratory Medicine, MMIMSR, M.M. Deemed to be University, Mullana, Ambala, Haryana, IN

Abstract

Aim: study the prevalence of various risk factors and co-morbidities in patients with acute exacerbation of chronic obstructive pulmonary disease. Material and Method: 73 patients admitted with AE-COPD data on body mass index (BMI), smoking, symptoms, co-morbidities course of the disease, spirometry management were obtained. Results: Eighty-eight percent of the admitted patients had current or past smoking habit of ‘Bidi’ and 9% were cigarette smokers. of admitted patients, 46% had at least one co-morbid condition. Mean FEV1 was 42.5%. Conclusion: Study concluded that the hospitalized patient with AE-COPD suggests spirometric impairments because majority of the patients had current or past smoking habits. Diabetes and cardiovascular diseases were found to be the major co-morbidities.

Keywords

AE-COD, Co-morbidities, FEV1.

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