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Wadkar, Ganesh
- Anti-ulcer Activity of Caesalpinia bonducella (Linn.) Flem. Leaves
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Journal of Natural Remedies, Vol 10, No 2 (2010), Pagination: 91-96Abstract
The purpose of the present study is to evaluate the anti-ulcer activity of Caesalpinia bonducella (Linn.) Flem. The methanolic extract of Caesalpinia bonducella (Linn.) Flem. leaves were evaluated for its anti-ulcer activity against aspirin plus pylorous ligation induced gastric ulcer (antisecretory) in rats, water immersion stress induced ulcer models in rats and HCl-Ethanol induced ulcer (cytoprotective) in mice at two different doses viz. 100 and 200 mg/ kg. Biochemical parameters like volume, pH, free acidity, total acidity of the gastric juice, ulcer index and percentage protection were studied. The methanolic extract of Caesalpinia bonducella leaves in aspirin plus pyrolus ligation showed significant (P<0.05, P<0.01) reduction in gastric volume, free acidity, total acidity and ulcer index at dose of 100 and 200 mg/kg as compared to control, there was marked increase in pH at dose of 100 and 200 mg/kg. The plant extract at both dose of 100 and 200 mg/kg showed significant gastro protective activity in water immersion stress induced ulcer and HCl-Ethanol induced ulcer. Thus, the present results indicate that the methanolic extract of Caesalpinia bonducella (Linn.) Flem. leaves have significant anti-ulcer activity.Keywords
Caesalpinia bonducella, Anti-ulcer, Aspirin Pylorus Ligation Ulceration, HCL-ethanol Ulceration, Water Stress Ulcer- Antioxidant Activity of Borassus flabellifer (linn.) Fruits
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1 K.L.E. University, Department of Pharmacognosy and Phytochemistry, J.N.M.C Campus, Nehru Nagar, Belgaum, Karnataka-590010, IN
1 K.L.E. University, Department of Pharmacognosy and Phytochemistry, J.N.M.C Campus, Nehru Nagar, Belgaum, Karnataka-590010, IN
Source
Asian Journal of Pharmacy and Technology, Vol 3, No 1 (2013), Pagination: 16-19Abstract
The fruit of Borassus flabellifer Linn. belonging to family Areaceae reported to be posses the antioxidant activity. The extracts have been also evaluated for antioxidant activity by using in-vitro methods DPPH (2, 2-Diphenyl-1 picryl hydrazyl) and ABTS (2, 2-azinobis-(3-ethylbenzo-thiazoline-6-sulfonic acid) assay. The phytochemical analysis carried out revealed the presence of saponins, tannins, flavonoids, carbohydrates, amino acids and phenolic compounds in the extracts.Keywords
Antioxidant, DPPH, ABTS, Borassus flabellifer LinnReferences
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