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Jain, D.
- Spectrophotometric Determination of Olopatadine Hydrochloride in Eye Drops and Tablets
Abstract Views :186 |
PDF Views:91
Authors
D. Jain
1,
P. K. Basniwal
2
Affiliations
1 School of Pharmaceutical Sciences, Rajiv Gandhi Technological University, Bhopal - 462033, Madhya Pradesh, IN
2 LBS College of Pharmacy, Udai Marg, Tilak Nagar, Jaipur-302004, Rajasthan, IN
1 School of Pharmaceutical Sciences, Rajiv Gandhi Technological University, Bhopal - 462033, Madhya Pradesh, IN
2 LBS College of Pharmacy, Udai Marg, Tilak Nagar, Jaipur-302004, Rajasthan, IN
Source
Journal of Pharmaceutical Research, Vol 12, No 2 (2013), Pagination: 48-52Abstract
Optimized and validated three UV spectrophotometric methods have been proposed for the determination of olopatadine hydrochloride in different dosage forms (eye drop and tablets) and bulk drug. The developed methods viz. linear regression equation (LRE), standard absorptivity (SA) and first order derivative (FOD) method were validated for linearity, accuracy, precision and robustness according to ICH guideline to assure reliability of the developed methods. The methods follow Beer-Lambert's law for the concentration of 10-50 μg mL-1. Validated methods were applied for determination of olopatadine hydrochloride content in tablet dosage forms as well as in eye drops with non-significant difference (P > 0.05) and can be successfully applied for routine analysis like assay, dissolution studies, bio-equivalence studies etc. in pharmaceutical industries.Keywords
Olopatadine HCI, Eye Drop, Tablets, UV Spectrophotometry.Full Text
- Purple Urine Bag Syndrome:An Uncommon Case Presentation
Abstract Views :165 |
PDF Views:0
Authors
Affiliations
1 Pt. B.D. Sharma University of Health Sciences, ROHTAK-124001 (Haryana), IN
2 Department of Gyane and Obstetrics, Pt. B.D. Sharma University of Health Sciences, ROHTAK-124001 (Haryana), IN
3 Dept. of Medicine, PGIMS, Rohtak-124001 (Haryana), IN
4 Department of Medicine, Pt. B.D. Sharma University of Health Sciences, ROHTAK-124001 (Haryana), IN
1 Pt. B.D. Sharma University of Health Sciences, ROHTAK-124001 (Haryana), IN
2 Department of Gyane and Obstetrics, Pt. B.D. Sharma University of Health Sciences, ROHTAK-124001 (Haryana), IN
3 Dept. of Medicine, PGIMS, Rohtak-124001 (Haryana), IN
4 Department of Medicine, Pt. B.D. Sharma University of Health Sciences, ROHTAK-124001 (Haryana), IN
Source
The Indian Practitioner, Vol 69, No 10 (2016), Pagination: 29-31Abstract
Purple urine bag syndrome (PUBS) is a rare condition indicating the presence of UTI characterized by intense purple discoloration of the urine. Although typically benign, purple urine is alarming to patients. This article presents the case of a chronically debilitated female patient whose urine became purple in the due course of hospital admission with indwelling urinary catheter in situ. The case report includes brief summary of PUBS, including its documented risk factors, the chemical chain reaction involved in producing purple urine, and how healthcare providers should treat patients when PUBS is encountered.Keywords
Purple Urine Bag Syndrome, Urinary Tract Infections, Chronic Catheterization.
References
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- Does Hemodialysis Improve Health-Related Quality of Life in Chronic Kidney Disease? A Tertiary Care Centre Experience
Abstract Views :191 |
PDF Views:1
Authors
Affiliations
1 Department of Medicine and Division of Nephrology, Pt. B.D. Sharma University of Health Sciences, Rohtak-124001 (Haryana), IN
1 Department of Medicine and Division of Nephrology, Pt. B.D. Sharma University of Health Sciences, Rohtak-124001 (Haryana), IN
Source
The Indian Practitioner, Vol 70, No 3 (2017), Pagination: 23-27Abstract
Introduction: Advances in dialysis procedures have improved treatment and prolonged lives of chronic kidney disease (CKD) patients. However, improving survival via dialysis is not enough. Assessment of health-related quality of life (HRQoL) in CKD patients has evolved with treatment advances so that the expectation of patient outcomes has grown from simple survival to achieving a sense of well-being.
Objective: To evaluate HRQoL scores with either Hemodialysis (HD) or non-dialysis-dependent advanced CKD.
Methods: Adults CKD patients with eGFR less than 30 ml/min/1.73 m2 were randomly selected and divided into two groups; group A and B. Group A consisted of patients on medical management without any renal replacement therapy and group B with patients undergoing thrice-weekly in-center HD for more than three months. All patients were assessed for HRQoL through the SF-36 questionnaire. Patients having psychiatric illness or cognitive dysfunction, transplanted kidney and haemodialysis less than three months were excluded from study.
Results: HRQoL composite summary scores were severely and significantly impaired in group B patients as compared to group A. The mean PCS scores in group A and B were 34.52±5.54 and 31.08±6.83, respectively and the difference being statistically significant. The MCS scores also showed a statistically significant difference among both groups.
Conclusion: In our study low scores were registered in both the composite summary scores of HRQoL in HD group of patients as compare to non-HD group Study points that care is often suboptimal by developed world standards.
Keywords
Chronic Kidney Disease, Health-Related Quality of Life, Renal Replacement Therapy, Hemodialysis.References
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