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Brindha, D.
- Antimicrobial Activity of White and Pink Nelumbo Nucifera Gaertn Flowers
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Asian Journal of Pharmaceutical Research and Health Care, Vol 2, No 2 (2010), Pagination: 147-155Abstract
Nelumbo nucifera Gaertn (Family: Nelumbonaceae), medicinally versatile and used as an important raw material of age-old traditional medical practices like Ayurveda and folk medicine. Bioassays for antimicrobial activities were carried out using hydroethanolic extract of both white and pink flowers of Nelumbo nucifera Gaertn plant. Both the flower extracts were tested against five important bacterial strains and two fungal strains. Further, Minimum Inhibitory Concentration (MIC) was evaluated against Escherichia coli (gram negative) and Staphylococcus aureus (gram positive) organisms. Both the flower extracts showed considerable activity against all tested bacteria and fungi strains. The white and pink flower extracts more or less showed similar antimicrobial activities. MIC for white flower extract against Escherichia coli and Staphylococcus aureus was found to be 430μg and 450μg respectively and pink flower showed 480μg and 490μg respectively. The antibacterial and antifungal activities of both flower extracts were comparable to those of selected chemical antibiotics suggesting their potential as alternatives to orthodox antibiotics in the treatment of infectious caused by these microorganisms.Keywords
Nelumbo nucifera Gaertn, Antibacterial Activity, Minimum Inhibitory Concentration (MIC), Antifungal Activity, Agar Disc Diffusion.- Phytochemical Screening, Antimicrobial Activity and Antimicrobial Finishing of Polyherbal Extract on Nonwoven Wound Dressing
Abstract Views :149 |
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Affiliations
1 Department of Costume Design and Fashion, PSG College of Arts and Science, Coimbatore, IN
2 Department of Home Science, Mother Teresa Women’s University, Coimbatore, IN
3 Department of Biochemistry, PSG College of Arts and Science, Coimbatore, IN
1 Department of Costume Design and Fashion, PSG College of Arts and Science, Coimbatore, IN
2 Department of Home Science, Mother Teresa Women’s University, Coimbatore, IN
3 Department of Biochemistry, PSG College of Arts and Science, Coimbatore, IN
Source
Research Journal of Pharmacy and Technology, Vol 12, No 2 (2019), Pagination: 632-636Abstract
Terminalia bellerica, Withania somnifera, Madhuca longifolia and Sygyzium cumini was selected for the current study based on its potent antimicrobial activity. The poly herbal plant extract was tested against nine clinical bacterial strains that are responsible for the wound infections. The FTIR and GCMS studies of the poly herbal plant extract revealed the presence of functional groups such as phenols, alcohol, amines, carbonyl group and components responsible for antimicrobial properties respectively. The phytochemical analysis showed the presence of bioactive principles such as alkaloids, flavanoids, phenols, steroids and tannins. The poly herbal extract was then coated on the TencelR nonwoven fabric using pad-dry-cure method. The antimicrobial efficacy of the coated fabrics exhibited better inhibitory activity against all the test organisms under the standard AATCC 147. The coated fabric also showed 8 mm zone of inhibition against Candida albicans. The results recommend the use of poly herbal plant extract can potentially be used as a substitute to synthetic agents. Also, it can be employed in non-implantable medical textiles such as wound dressings to prevent the microbial infestation and also to reduce the bio burden in wound therapy.Keywords
Antibacterial Susceptibility, Non-Implantable, Nonwoven, Wound Dressing, Wound Infections.References
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