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Varshitha, C.
- Antidiabetic Activities of Euphorbia nivulia Buch in Alloxan Induced Diabetic Rats
Abstract Views :258 |
PDF Views:2
Authors
Affiliations
1 Department of Pharmacology, Gautham College, Bengaluru–32, IN
1 Department of Pharmacology, Gautham College, Bengaluru–32, IN
Source
Research Journal of Pharmacology and Pharmacodynamics, Vol 6, No 1 (2014), Pagination: 8-12Abstract
Diabetes is a group of metabolic diseases in which a person has high blood sugar, either because the body does not produce enough insulin or because cells do not respond to the insulin that is produced. This high blood sugar produces the classical symptoms of polyuria (frequent urination), polydipsia (increased thirst) and polyphagia (increased hunger). Diabetes mellitus is often called 'The silent killer', because it causes serious complications without serious symptoms and can affect many of major organs in the body. In the present study diabetes was induced in albino rat models with alloxan monohydrate. Euphorbia nivulia Buch, has been claimed to possess antidiabetic properties in Ayurveda medicine system. The present study was undertaken to screen the hypoglycemic activity of petroleum ether, methanolic and aqueous extracts of Euphorbia nivulia (100mg/kg., b.w.). All the extracts at 100mg/kg., b.w. showed significant decrease in blood glucose level. It also showed the significant response in blood serum parameters (albumin, urea, creatnine, and total protein) lipid parameters such as total cholesterol, LDL, HDL, VLDL and TG when compared with diabetic control.Keywords
Alloxan, Euphorbia nivulia Buch, Diabetes Mellitus, Blood Glucose, Lipid Profile And Blood Serum Parameters.
References
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- Anti-Obesity Activities of Hydro-Alcoholic Extract of Echinochloa crusgalli (L.) P. Beauv Grains in Albino Rats
Abstract Views :283 |
PDF Views:3
Authors
Affiliations
1 Department of Pharmacology, Gautham College of Pharmacy, Bangalore, Karnataka, IN
1 Department of Pharmacology, Gautham College of Pharmacy, Bangalore, Karnataka, IN
Source
Research Journal of Pharmacology and Pharmacodynamics, Vol 6, No 1 (2014), Pagination: 13-20Abstract
Obesity is often defined simply as a condition of abnormal or excessive fat accumulation in adipose tissue, to the extent that health may be impaired. The present study was undertaken to evaluate anti-obesity effect of hydro-alcoholic extracts of Echinochloa crusgalli on high fat diet induced obesity in albino rats. Obesity was induced by administration of high fat diet for 4 weeks with normal diet and obtained obese rats were treated with Echinochloa crusgalli in a dose of 200, 400 and 600 mg/kg, b.w. p.o for next 4 weeks. It showed significant decrease in body weights, adipose tissue weight, SGOT and SGPT levels, blood glucose levels, LDL-C, VLDL-C, total cholesterol, triglyceride levels, atherogenic index, and also showed significant increase in HDL-C levels when compared with high fat diet control.Keywords
Obesity, Echinochloa crusgalli, High Fat Diet, Body Weight, Adipose Tissue Weight, Lipid Profile, Atherogenic Index, Serum Blood Glucose Levels.References
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