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Vijayakumar, B.
- Post-Coital Antiimplantation and Pregnancy Interruption Potency of the Seeds of Crotalaria juncea Linn
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1 Reproductive Biology Laboratory, Department of Post-Graduate Studies and Research in Zoology, Gulbarga University, Gulbarga-585106, IN
1 Reproductive Biology Laboratory, Department of Post-Graduate Studies and Research in Zoology, Gulbarga University, Gulbarga-585106, IN
Source
Journal of Endocrinology and Reproduction, Vol 7, No 1&2 (2003), Pagination: 69-69Abstract
The petroleum ether, benzene and alcohol extracts of the seeds of C.juncea were tested for antiimplantation and pregnancy interruption activities in female albino rats. Out of these three extracts the alcohol extract was found to be the most effective in causing antiimplantation and pregnancy interruption activities. These adverse effects on fertility are reversible on withdrawl of the treatment of the extracts. The alcohol extract upon testing showed to possess estrogenic activity. Among the three extracts subjected to preliminary phytochemical screening, the alcohol extract showed positive tests for alkaloids, steroids, glycosides, saponins, flavonoides, fixed oils, phenols and tannins.- Extractive Spectrophotometric Methods for Determination of Esmolol Hydrochloride Using Acidic Triphenylmethane Dyes
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1 Department of Chemistry, Nizam College (O.U), Hyderabad, 500001, IN
1 Department of Chemistry, Nizam College (O.U), Hyderabad, 500001, IN
Source
Asian Journal of Research in Chemistry, Vol 4, No 11 (2011), Pagination: 1789-1792Abstract
Three simple and sensitive extractive spectrophotometric methods have been described for the assay of Esmolol hydrochloride either in pure form or in pharmaceutical formulations. The developed methods involve formation of coloured chloroform extractable ion-pair complexes of the drug with bromothymol blue (BTB), bromophenol blue (BPB) and bromocresol green (BCG) in acidic medium. The extracted complexes showed absorbances maxima at 415,412 and 412nm with BTB, BPB and BCG respectively. Beer's law is obeyed in the concentration ranges 2.5- 25μg/ml for all three dyes. The effect of concentration of dye and pH have been studied and optimized. The limits of detection and quantification have been determined for three methods. All the three methods have been validated as per the guidelines of ICH. The methods have been applied to the determination of drug in commercial tablets and results of analysis were validated statistically through recovery studies.Keywords
Esmolol Hydrochloride, Bromothymol Blue, Bromophenol Blue, Bromocresol Green, Spectrophotometry.- Extractive Spectrophotometric Methods for Determination of Moxifloxacin Hydrochloride Using Acidic Triphenylmethane Dyes
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Authors
Affiliations
1 Department of Chemistry, Nizam College (O.U), Hyderabad, 500001, IN
1 Department of Chemistry, Nizam College (O.U), Hyderabad, 500001, IN