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Sharma, Aryan
- Use of Custom-Made Antibiotic Coated Intra-Medullary Nail in Treatment of Infected Non-Union of Long Bones
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Authors
Vineet Pruthi
1,
Ashwani Ummat
2,
Manjeet Singh
3,
Sonia Kochhar
4,
Subodh Pathak
5,
Vishesh Verma
1,
Aryan Sharma
1
Affiliations
1 PG Resident MS Orthopaedics, Maharishi Markandeshwar Deemed to be University, Mullana, Ambala, IN
2 Professor Department of Orthopaedics, Maharishi Markandeshwar Deemed to be University, Mullana, Ambala, IN
3 Professor and Head, Department of Orthopaedics, Maharishi Markandeshwar Deemed to be University, Mullana, Ambala, IN
4 Associate. Professor, Department of Physiology, AIIMS, Bathinda5, IN
5 Assistant Professor, Department of Orthopaedics, Maharishi Markandeshwar Deemed to be University, Mullana, Ambala, IN
1 PG Resident MS Orthopaedics, Maharishi Markandeshwar Deemed to be University, Mullana, Ambala, IN
2 Professor Department of Orthopaedics, Maharishi Markandeshwar Deemed to be University, Mullana, Ambala, IN
3 Professor and Head, Department of Orthopaedics, Maharishi Markandeshwar Deemed to be University, Mullana, Ambala, IN
4 Associate. Professor, Department of Physiology, AIIMS, Bathinda5, IN
5 Assistant Professor, Department of Orthopaedics, Maharishi Markandeshwar Deemed to be University, Mullana, Ambala, IN
Source
Indian Journal of Public Health Research & Development, Vol 11, No 2 (2020), Pagination: 802-807Abstract
Introduction: In cases of infected Nonunion of long bones Antibiotic coated nail provides mechanical support for the affected bone with delivery of high concentration of antibiotics for infection control and a conclusive environment for fracture healing. The aim of the study was to observe and study the treatment of infected non-union of long bones with antibiotic coated nailing in infection control and bony union. Material and Method: The study was conducted on 30 patients (male and female between the age of 18‑70 years). All patient on admission were subjected to detailed history, relevant investigations and thorough clinical examinations. Minimum follow-up period was 6 months. Radiological and blood investigations were done for infection control and bony union. Result: In the current study of 30 patients with mean age of 43.67 years, Infection control and bony union was achieved in 27 patients without any need for subsequent procedures. Current study provides an alternative to external fixation alone as a means of stabilizing non-unions while providing a high concentration of antibiotic locally for combating this difficult problem. Conclusion: The clinical results and final outcome after antibiotic coated I.M. nailing in infected nonunion of long bones are both satisfactory and reproducible as evident by the comparison of this present study with the previous literature available.Keywords
Infected nonunion, antibiotic coated nail.- Study of Correlation of Hyperuricemia with Knee Osteoarthritis
Abstract Views :518 |
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Authors
Rajdeep Singh Bajwa
1,
Rakesh Gautam
2,
Subodh K. Pathak
3,
Aryan Sharma
1,
Vineet Pruthi
1,
Vishesh Verma
1
Affiliations
1 PG Resident M/S Orthopaedics, Department Orthopaedics, Maharishi Markandeshwar Deemed to be University, Mullana, Ambala, IN
2 Associate Professor,Department Orthopaedics, Maharishi Markandeshwar Deemed to be University, Mullana, Ambala, IN
3 Assistant Professor, Department Orthopaedics, Maharishi Markandeshwar Deemed to be University, Mullana, Ambala, IN
1 PG Resident M/S Orthopaedics, Department Orthopaedics, Maharishi Markandeshwar Deemed to be University, Mullana, Ambala, IN
2 Associate Professor,Department Orthopaedics, Maharishi Markandeshwar Deemed to be University, Mullana, Ambala, IN
3 Assistant Professor, Department Orthopaedics, Maharishi Markandeshwar Deemed to be University, Mullana, Ambala, IN
Source
Indian Journal of Public Health Research & Development, Vol 11, No 2 (2020), Pagination: 945-949Abstract
The present study was conducted to identify the link between increased uric acid and osteoarthritis and to find out the prevalence of hyperuricemia in population suffering from osteoarthritis of knee. Material and Method: The study was conducted on 100 patients (male and female between the age of 40- 70 years) with knee pain for more than 6 weeks to establish a correlation between knee osteoarthritis and hyperuricemia. Result: In the current study female preponderance was seen. Mean age of the patients was 50.10 years and maximum patients were in the age group of 40-50 years. KOA patients had higher values of uric acid as compared to patients without KOA however no stastically significant relation was found between increasing uric acid levels and severity of KOA with p-value .668 being insignificant. The mean BMI of patients with KOA was higher than the patients without KOA but no statistical significant relation was found between increased incidence of KOA in females as compared to males with increasing BMI p-value 0.777 being insignificant. There was no statistically significant correlation between hyperuricemia and either gender with p-value being >.0.05 (0.119). VAS and WOMAC scoring was done at 0 and 16 weeks however no significant improvement was seen except for the pain component which improved in KOA patients. Conclusion: In this present study we observed increased prevalence of OA knee in females and in patients with hyperuricemia and also with patients with higher BMI. Serum levels of CRP and ESR also show positive prevalence in patients with KOA in this study. However, no s statistically significant correlation was observed between levels of hyperuricemia and severity of KOA. Hence in conclusion our study points towards positive correlation between hyperuricemia and KOA. Limitations of our study included inability to homogenise groups in terms of BMI, age, activity level, smoking, alcohol etc.Keywords
Knee osteoarthritis, Hyperuricemia, WOMAC Score- Characterization of the Second Wave of COVID-19 in India
Abstract Views :210 |
PDF Views:82
Authors
Affiliations
1 Department of Aerospace Engineering, Indian Institute of Technology, Kanpur 208 016, India, IN
2 Department of Physics, Indian Institute of Technology, Kanpur 208 016, India, IN
1 Department of Aerospace Engineering, Indian Institute of Technology, Kanpur 208 016, India, IN
2 Department of Physics, Indian Institute of Technology, Kanpur 208 016, India, IN
Source
Current Science, Vol 121, No 1 (2021), Pagination: 85-93Abstract
The second wave of COVID-19, which began in India around 11 February 2021, has hit the country hard with daily cases reaching nearly triple the first peak value as on 19 April 2021. The epidemic evolution in India is complex due to regional inhomogeneities and the spread of several coronavirus mutants. In this study, we characterize the virus spread in the ongoing second wave in India and its states until 19 April 2021, and also examine the dynamic evolution of the epidemic from the beginning of the outbreak. Variations in the effective reproduction number (Rt) are taken as quantifiable measures of virus transmissibility. Rt value for every state, including those with large rural populations, is greater than the self-sustaining threshold of 1. An exponential fit on recent data also shows that the infection rate is much higher than in the first wave. Subsequently, characteristics of COVID-19 spread are analysed region-wise, by estimating test positivity rates (TPRs) and case fatality rates (CFRs). Very high TPR values for several states present an alarming situation. CFR values are lower than those in the first wave, but are recently showing signs of increase as the healthcare system is being over-stretched with the surge in infections. Preliminary estimates with a classical epidemiological model suggest that the peak for the second wave could occur around mid-May 2021, with daily count exceeding 0.4 million. The study strongly suggests that an effective administrative intervention is needed to arrest the rapid growth of the epidemic.Keywords
Coronavirus, COVID-19, Epidemic Evolution, Reproduction Number, Second Wave.References
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