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- Aishwarya Sahu
- Akansha Yadav
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- Chandrashekhar Nayak
- Dev Kumar
- Harshita Yarda
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Jaiswal, Akash
- A Short Review on the Formulation of Transdermal Dermal Drug Delivery System (TDDS)
Abstract Views :452 |
PDF Views:0
Authors
Alok Ranjan
1,
Aishwarya Sahu
1,
Akansha Yadav
1,
Alka Payasi
1,
Akash Jaiswal
1,
Akshay Kumar
1,
Akash Sahu
1,
Ashwani Jangde
1,
Chandrashekhar Nayak
1,
Dev Kumar
1,
Harshita Yarda
1,
Mitali Sahu
1,
Nokesh Sahu
1,
Rajesh Patel
1,
Nisha Nair
1,
Mukta Agrawal
1,
Ajazuddin
1,
D. K. Tripathi
1,
Amit Alexander
1
Affiliations
1 Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai - 490024, Chhattisgarh, IN
1 Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai - 490024, Chhattisgarh, IN
Source
Research Journal of Pharmaceutical Dosage Form and Technology, Vol 10, No 2 (2018), Pagination: 90-94Abstract
The transdermal drug delivery systems (TDDS) are drug delivery system that gives rapid, the immediate therapeutic effect of the drug across the patient’s skin and its different layers. They are also called as patches. More than 75% of the drugs, now a day’s, are taken orally and are not very much effective. To overcome these problems, the transdermal drug delivery system has been evolved. The advantage of transdermal patches is that they deliver the drugs for better systemic effects at a controlled and a predetermined rate. This drug delivery system also endorses the controlled release of drug medicament into the skin of the patients. The chief aim of this drug delivery system is to deliver the drug contents into the systemic circulation through the permeation of skin at a predetermined rate. This article is an overview of different types of transdermal patches, their various method of preparation as well as their various physicochemical evaluation methods. The present study is performed for the motivation of the graduates towards publication and research. Hence, we have encouraged the graduates to prepare an informative article on the present subject.Keywords
TDDS, Systemic Circulation, Transdermal Patches, Systemic Effects, Drug Medicament, Novel Drug Delivery System.References
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- Formulation and Evaluation of Emulgel for Topical Delivery of Dexibuprofen
Abstract Views :70 |
PDF Views:0
Authors
Rina Maskare
1,
Shital Thakre
1,
Vithika Gupta
1,
Manisha Basantwani
1,
Ayush Kshirsagar
1,
Triveni Bahekar
1,
Akash Jaiswal
1
Affiliations
1 Manoharbhai Patel Institute of B-Pharmacy, Kudwa, Gondia-441614, Maharashtra., IN
1 Manoharbhai Patel Institute of B-Pharmacy, Kudwa, Gondia-441614, Maharashtra., IN
Source
Research Journal of Pharmacy and Technology, Vol 15, No 2 (2022), Pagination: 745-750Abstract
An emulgel formulation was developed for a topical non-steroidal anti-inflammatory agent using carbopol as the gelling agent. The effect of concentrations of oil, surfactant and gelling agent on the in-vitro drug release pattern was investigated using 23 factorial design. The optimized emulgel formulations were characterized for appearance, color, pH, homogeneity, viscosity and spreadability. The in-vitro release profile drug from the emulgel formulation was strongly affected by the concentration of gelling agent, surfactants and oil. Stability studies were conducted at different temperatures and humidity conditions that indicated the formulations to be stable under accelerated conditions. No erythema or irritation was observed during the skin irritation studies on rabbits. Optimized formulation showed comparable analgesic and anti-inflammatory activity when they compared with marketed Nurofen gel. So, it can be concluded that topical emulgel of dexibuprofen posses an effective anti-inflammatory and analgesic activity.Keywords
Dexibuprofen, Topical drug delivery, Anti-inflammatory, Analgesic, NASAIDs.References
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