A B C D E F G H I J K L M N O P Q R S T U V W X Y Z All
Sagri, Aaisha
- Evaluation of Antimicrobial Potency and Synergistic Activity of Nine Traditionally Used Indian Medicinal Plants
Authors
1 M. C. E. Society’s Allana College of Pharmacy, Azam Campus, Camp, Pune, 411001, Maharashtra, IN
2 M.C.E. Society’s Allana College of Pharmacy, Pune, IN
3 Abeda Inamdar Senior College for Girls, Pune, IN
Source
Research Journal of Pharmacognosy and Phytochemistry, Vol 2, No 2 (2010), Pagination: 131-135Abstract
Recent acceptance of natural herbal medicines as an alternative form of health care and development of microbial resistance has led to investigate the antimicrobial action of medicinal plants. Present investigation is focused on antimicrobial potential of nine commonly used Indian medicinal herbs. The antimicrobial screening of hydroalcoholic extract of all the nine plants was carried out by agar welldiffusion method and broth dilution method. The efficacy of extracts has been evaluated in terms of minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) against pathogenic strains of Staphylococcus aureus (ATCC 6538), Pseudomonas aeruginosa (ATCC 9027) and Candida albicance (ATCC 10231). MIC values of individual extracts ranged between 0.4-0.9 mg/ml. MIC values of the combined crude extracts were recorded as 0.3 mg/ml (C. albicance ) , 0.5 mg/ml (Staph. aureus), and 0.6 mg/ml (P. aeruginosa) . The MIC values obtained in each test organisms were inhibitory as well as cidal values. Susceptibility of test organisms was in decreasing order C. albicance > Staph . aureus > P. aeruginosa. Thus our findings validate the use of these medicinal plants in traditional systems of medicines and their potential role in antimicrobial therapy.
Keywords
Antimicrobial Activity, Hydro Alcoholic Extract, Synergistic Activity.- Pharmacognostic and Phytochemical Evaluation of Quirivelia frutescens (Apocynaceae)
Authors
1 M.C.E. Society’s Allana College of Pharmacy, Pune-01, MS, IN
Source
Asian Journal of Research in Chemistry, Vol 2, No 4 (2009), Pagination: 509-512Abstract
Quirivelia frutescens (Apocynaceae) also known as kalidudhi or shymlata is much branched twining shrub of West Bengal. It is used by natives as wound healing, digestive etc. However the plant is not much explored pharmacognostically and phytochemically, therefore the aim of this study was to evaluate pharmacognostic and phytochemical characteristics of plant Quirivelia fructescens. Microscopy of leaves showed distinct bicollateral vascular bundle,single layer of palisade, and well defined anomocytic stomata. Presence of calcium oxalate crystal in the form of thin pointed needle and xylem vessels with circular bordered pits were observed in the stem.The total ash, acid insoluble and water-soluble ash were found to be within the limit as compared to other plants belonging to Apocyanaceae family. The preliminary phytochemical studies indicated the presence of alkaloids and tannins. Phytochemical analysis, like TLC, UV, IR NMR, GCMS, were carried out by using the extract of stem. In TLC, the Rf value was found to be 0.77, which is near to many alkaloids. In C13 NMR, the peak showed the presence of unsaturation between conjugated carbon of alkaloid and steroid group and saturated ring substituted with aliphatic chain. GCMS study showed the presence of eight chemicals constituent in the extract. In UV, the λmax was found between 331 to 337 nm and peak indicated the presence of unsaturation.
Thus, from the above study, it can be concluded that the plant Quirivalia fructescens, has rich content of alkaloid, steroid and tannins.