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Software-Assisted Depth Analysis of Optic Nerve Stereoscopic Images in Telemedicine


Affiliations
1 The Institute of Ophthalmology and Visual Science, Rutgers New Jersey Medical School, Newark, NJ 07103, United States
 

Background: Software guided optic nerve assessment can assist in process automation and reduce interob server disagreement.We tested depth analysis software (DAS) in assessing optic nerve cup-to-disc ratio (VCD) from stereoscopic optic nerve images (SONI) of normal eyes. Methods: In a prospective study, simultaneous SONI from normal subjects were collected during telemedicine screenings using a Kowa 3Wx nonmydriatic simultaneous stereoscopic retinal camera (Tokyo, Japan). VCD was determined from SONI pairs and proprietary pixelDAS (Kowa Inc., Tokyo, Japan) after disc and cup contour line placement. Anonstereoscopic VCD was determined using the right channel of a stereo pair. Mean, standard deviation, t-test, and the intraclass correlation coefficient (ICCC) were calculated. Results: 32 patients had mean age of 40 ± 14 years. Mean VCD on SONI was 0.36 ± 0.09, with DAS 0.38 ± 0.08, and with nonstereoscopic 0.29 ± 0.12. The difference between stereoscopic and DAS assisted was not significant (p = 0.45). ICCC showed agreement between stereoscopic and software VCD assessment. Mean VCD difference was significant between nonstereoscopic and stereoscopic (p < 0.05) and nonstereoscopic and DAS (p < 0.005) recordings. Conclusions: DAS successfully assessed SONI and showed a high degree of correlation to physician-determined stereoscopic VCD.
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  • Software-Assisted Depth Analysis of Optic Nerve Stereoscopic Images in Telemedicine

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Authors

Tian Xia
The Institute of Ophthalmology and Visual Science, Rutgers New Jersey Medical School, Newark, NJ 07103, United States
Shriji N. Patel
The Institute of Ophthalmology and Visual Science, Rutgers New Jersey Medical School, Newark, NJ 07103, United States
Ben C. Szirth
The Institute of Ophthalmology and Visual Science, Rutgers New Jersey Medical School, Newark, NJ 07103, United States
Anton M. Kolomeyer
The Institute of Ophthalmology and Visual Science, Rutgers New Jersey Medical School, Newark, NJ 07103, United States
Albert S. Khouri
The Institute of Ophthalmology and Visual Science, Rutgers New Jersey Medical School, Newark, NJ 07103, United States

Abstract


Background: Software guided optic nerve assessment can assist in process automation and reduce interob server disagreement.We tested depth analysis software (DAS) in assessing optic nerve cup-to-disc ratio (VCD) from stereoscopic optic nerve images (SONI) of normal eyes. Methods: In a prospective study, simultaneous SONI from normal subjects were collected during telemedicine screenings using a Kowa 3Wx nonmydriatic simultaneous stereoscopic retinal camera (Tokyo, Japan). VCD was determined from SONI pairs and proprietary pixelDAS (Kowa Inc., Tokyo, Japan) after disc and cup contour line placement. Anonstereoscopic VCD was determined using the right channel of a stereo pair. Mean, standard deviation, t-test, and the intraclass correlation coefficient (ICCC) were calculated. Results: 32 patients had mean age of 40 ± 14 years. Mean VCD on SONI was 0.36 ± 0.09, with DAS 0.38 ± 0.08, and with nonstereoscopic 0.29 ± 0.12. The difference between stereoscopic and DAS assisted was not significant (p = 0.45). ICCC showed agreement between stereoscopic and software VCD assessment. Mean VCD difference was significant between nonstereoscopic and stereoscopic (p < 0.05) and nonstereoscopic and DAS (p < 0.005) recordings. Conclusions: DAS successfully assessed SONI and showed a high degree of correlation to physician-determined stereoscopic VCD.