Indian Journal of Public Health Research & Development

S. Sindhuja ¹, J. Bhuvaneswarri ¹, Mohan Valiathan ¹, J. Bhaskar ¹

Affiliations
1 Department of Periodontics, Sree Balaji Dental College and Hospital, BIHER, Chennai, IN

Abstract

Periodontitis is a chronic inflammatory condition, caused by bacteria, that leads to the destruction of supporting tissues around teeth, resulting ultimately in significant morbidity as a result of infection, pain and tooth loss. Curcumin, from the ischolar_main of the turmeric plant Curcuma longa, is an extended pseudo symmetric polyphenol. In recent years, in vitro and in vivo research has suggested that curcumin has anticarcinogenic, antiviral, antioxidant and anti-inflammatory effects. The aim of this review is to systematically evaluate the clinical efficacy and anti inflammatory property of curcumin in periodontal disease. An electronic search was carried out using the keywords ‘curcumin’, ‘periodontal’ and ‘periodontitis’ via the PubMed/Medline, ISI Web of Science and Google Scholar databases for relevant articles published from 2009 to February 2019.

Keywords

Curcumin, Periodontal, Periodontitis, Inflammation.

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Swetha Gadde ¹, J. Judith Christina ², P. Surendranath ³, Bagavad Gita ⁴, Mohan Valiathan ⁵, Anitha Balaji ⁵

Affiliations
1 Senior Lecturer, Department of Periodontics, Ragas Dental College, Chennai, IN
2 Post Graduate Student, Department of Periodontics, Sree Balaji Dental College and Hospital, BIHER, Chennai, IN
3 Post Graduate Student, Department of Periodontics, Sree Balaji Dental College and Hospital, BIHER, Chennai, IN
4 Head of the Department, Department of Periodontics, Sree Balaji Dental College and Hospital, BIHER, Chennai
5 Professor, Department of Periodontics, Sree Balaji Dental College and Hospital, BIHER, Chennai, IN

Abstract

Background: The aim of the present study is to assess salivary Thiobarbituric Acid Reactive Substances (TBARS) levels in pregnant and non-pregnant women with gingivitis before and after scaling.

Materials and Method: Fifteen subjects (Non-pregnant) were selected out of the patients who attended the Department of Periodontics, Sree Balaji Dental College, Pallikaranai, Chennai. Fifteen subjects (Pregnant second trimester) were selected out of the patients who attended Velachery K.S Hospital, Chennai. Periodontal examination is done and again evaluated after scaling (30 days). Collection of saliva and assessment of TBARS is done. Assessment of TBARS is done by TBARS assay using thiobarbituric acid as a reagent. Statistical analysis done using student T test.

Results: Results indicated that the level of salivary TBARS in non-pregnant individuals after scaling is reduced and is statistically significant and the level of salivary TBARS in pregnant individuals after scaling also reduced but it is not statistically significant.

Conclusion: Gingivitis in pregnancy is not a contributing factor for the oxidative stress.

Keywords

Oxidative Stress, Salivary TBARS, Pregnancy, Reactive Oxygen Species.

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J. Bhuvaneswarri ¹, A. S. Sindhuja ², Bagavad Gita ³, Mohan Valiathan ¹

Affiliations
1 Professor, Department of Periodontics, Sree Balaji Dental College And Hospital, BIHER, Chennai, IN
2 Post Graduate, Department of Periodontics, Sree Balaji Dental College And Hospital, BIHER, Chennai, IN
3 Professor and Head of the Department, Department of Periodontics, Sree Balaji Dental College And Hospital, BIHER, Chennai, IN

Abstract

Fibroma is a benign tumor in which fibroblasts proliferate to form neoplasia, resulting in an increase in collagen fibers. Many of the fibroma-like lesions seen in the oral mucosa represent reparative or reactive hyperplasia of fibrous tissue against chronic irritation, and true neoplastic lesions are considered rare. Peripheral ossifying fibroma (POF) is a non-neoplastic, reactive lesion of gingiva. The precise etiopathogenesis of POF is unclear. However, it is suggested to originate from the connective tissue of periodontal ligament. This lesion predominantly occurs in the maxillary anterior region. The treatment protocol involves surgical excision followed by the biopsy of lesion. The high recurrence rate of the lesion is due to its reactive nature and unpredictable course. Hence proper postoperative monitoring and follow-up of the lesion are necessary. The present case was surgically managed and did not show any sign of recurrence during the follow-up period of 7 months.

Keywords

Peripheral Ossifying Fibroma, Fibroma, Non-Neoplastic Lesion, Inflammatory Growth.

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