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Jeevitha, M.
- Antimicrobial Activity of Silver Nanoparticles Synthesized using Marine Brown Seaweed Spatoglossum asperum against Oral Pathogens
Authors
1 Senior Lecturer, Department of Pharmacology, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, IN
2 Associate Professor, Department of Pharmacology, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, IN
Source
Indian Journal of Public Health Research & Development, Vol 10, No 11 (2019), Pagination: 3568-3573Abstract
Background: Green synthesis of nanoparticles using plant extract, bacteria, fungi and enzymes are ecofriendly and cost effective which do not need high pressure, energy, temperature and toxic chemicals for its synthesis protocol.
Materials and Method: In this report, we used the extract of marine brown algae Spatoglossum asperum to synthesize silver nanoparticles and were characterized using UV-visible spectrophotometer, TEM, XRD and FTIR and were also tested for their antimicrobial activity.
Results: These biosynthesized silver nanoparticles exhibited potent antimicrobial activity against oral pathogens namely, Streptococcus mutans, Enterococcus faecalis, Pseudomonas aeruginosa and Candida albicans and can be developed as a novel medicine against pathogenic oral diseases.
Conclusion: With increasing demand in advancements in diagnosis and treatment modalities, green synthesis of silver nanoparticles using marine brown algae Spatoglossum asperum has potent antimicrobial action have wider applications in dentistry.
Keywords
Spatoglossum asperum, Silver Nanoparticles, Marine Algae, Green Synthesis, Antimicrobial Activity.
- Anticariogenic Activity of Fresh Aloe vera Gel Mediated Copper Oxide Nanoparticles
Authors
1 Associate Professor, Department of Pharmacology, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, IN
2 Researcher, Department of Pharmacology, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, IN
3 Senior Lecturer, Department of Periodontics, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, IN
4 Researcher, Department of Biotechnology, School of Biosciences and Technology, VIT, Vellore, Tamil Nadu, IN
Source
Indian Journal of Public Health Research & Development, Vol 10, No 11 (2019), Pagination: 3664-3667Abstract
Background: Biosynthesis of metallic nanoparticles for its medical applications has become a major focus in nanotechnology in the recent years. Aloe vera has a wide spectrum of medicinal applications due to its anti-inflammatory, antimicrobial, anticancer and wound healing properties. Copper oxide nanoparticles have effective antimicrobial action against a wide range of pathogens and also dug resistant bacteria.
Materials and Method: In the present study, Aloe vera gel is used to synthesize copper oxide nanoparticles and were characterized using UV-visible spectrophotometry and FT-IR. The anticariogenic activity of oral pathogens namely, Staphylococcus aureus, Streptococcus mutans, Enterococcus faecalis, Pseudomonas sp, were also tested.
Results: UV absorption spectra of the synthesized nanoparticles revealed an intense surface plasmon resonance between 250 and 300. The functional groups in the copper oxide nanoparticles were determined by FT-IR and these also shown to have potent anticariogenic activity.
Conclusion: Copper oxide nanoparticles synthesized using Aloe vera gel shown to have an excellent anticariogenic activity and has a wide array of dental applications.