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Jeganathan, Jayakumar
- A Study of Postinfectious Glomerulonephritis in Adults
Authors
1 Dept of Nephrology, Kasturba Medical College-Mangalore, Manipal Academy of Higher Education, Karnataka, IN
2 Dept of Medicine, Kasturba Medical College-Mangalore, Manipal Academy of Higher Education, Karnataka, IN
Source
Indian Journal of Public Health Research & Development, Vol 10, No 12 (2019), Pagination: 124-126Abstract
Introduction: To study the clinical presentation and outcome of postinfectious glomerulonephritis in adults.
Materials and Method: This was a prospective study of 50 cases of post-infectious glomerulonephritis. All patients were followed up for 18 months. The mode of presentation, history of sore throat or skin infections were documented. Serum creatine, Urinary proteinuria, C3 level, and ASO titre were performed.All these patients were followed up every two weeks after discharge for six months and four weekly thereafter for one year. Outcomes were classified as complete remission, partial remission and development of end stage renal disease.
Results: In their presentation to the hospital Oedema was present in 98% of the cases. 84% of patients had oliguria, Gross haematuria was present in 24% of patients and hypertension was present in 92% of the patients. ASO titre was positive in 16% of the patients. Most patients (82%) had proteinuria between 2.5-3.5 gm/24hrs. Complete remission was achieved in 84% of the patients. Partial remission in 12% of the cases and 4% of the patients went on to develop end stage renal disease (ESRD). The presence of gross haematuria and nephrotic range proteinuria correlated with the development of end stage renal disease
Conclusion: Gross haematuria, nephrotic proteinuria, impaired renal function and presence of crescents in kidney biopsy at intial presentation are poor prognostic indicators of post-infectious glomerulonephritis in adults.
Keywords
Glomerulonephritis, Postinfectious, Proteinuria, Outcomes, Prospective.
- Factors Influencing the Development of Chronic Cough Following Common Cold
Authors
1 Kasturba Medical College, Mangaluru, IN
2 Kasturba Medical College, Manipal Academy of Higher Education, Mangaluru, IN
Source
Indian Journal of Public Health Research & Development, Vol 10, No 11 (2019), Pagination: 105-107Abstract
Introduction: Following common cold most of the patients recover within a week. However a few people go on to develop chronic cough. There have been no studies looking at simple patient characteristics which may tell us which patients may go on to develop chronic cough.
Materials and method: The main Aim was to study factors that determine which group of patients develop chronic cough following common cold. A total of 131 patients were included in the study. They were followed up for 3 weeks. They were divided into 2 groups based on whether they had cough for more than 3 weeks and less than 3 weeks. The collected data was analyzed using Chi square test.
Results: Among 131 individuals who underwent study 45 had chronic cough. Age group less than 20 yrs and more than 60 years, smoking history and a low PEFR (Peak Expiratory flow rate) were associated with development of chronic cough.
Conclusion: Extremes of age, smoking history and low PEFR were associated with the development of chronic cough following common cold.