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Hemashree, J.
- Evaluation of Malondialdehyde, Glutathione Peroxidase and Defensin Levels in Patients with and without Periodontitis
Authors
1 Graduate Student, Department of Biochemistry, Saveetha Dental College & Hospital, Saveetha Institute of Medical and Technical Sciences, Chennai, IN
2 Reader, Department of Biochemistry, Saveetha Dental College & Hospital, Saveetha Institute of Medical and Technical Sciences, Chennai, IN
3 Assistant Professor, Department of Biochemistry, Saveetha Dental College & Hospital, Saveetha Institute of Medical and Technical Sciences, Chennai, IN
Source
Indian Journal of Public Health Research & Development, Vol 11, No 1 (2020), Pagination: 246-250Abstract
Aim: Aim of the study is to estimate the levels of Malondialdehyde, glutathione peroxidase and Defensin levels on patients with and without periodontitis.
Materials and Method: The levels of Malondialdehyde and Glutathione peroxidase was estimated using colorimetric estimation and Defensin was estimated using ELISA.
Results: Levels of Defensin is increased in patients with periodontitis 9.18+-1.72 when compared to healthy subjects 6.22+-2.73. The mean levels of MDA is increased in patients with periodontitis 2.35+-0.32 when compared to normal patients 3.58+-0.36. The levels of Gpx is lower in patients with periodontitis 2.52+-0.58 when compared to normal patients 3.58+-0.36. The p-value was found to be significant (0.001).
Conclusion: Thus, this study reveals that Malondialdehyde, Defensin and glutathione peroxidase can be considered as biomarkers in the periodontal diseases.