Indian Journal of Public Health Research & Development

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ABO Blood Group and Secretor Status in IHD Patients


Affiliations
1 Dept. of Physiology, MRMC, Gulbarga, India
2 Dept. of Anatomy, MRMC, Gulbarga, Karnataka, India
     

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Various studies have been done trying to relate ABO blood groups with diseases e.g. Peptic ulcer, duodenal ulcer, pernicious anaemia, gallstones, carcinoma of stomach and IHD. The same blood group antigens are secreted in the body fluids. The blood group antigens have protective action on its secreting mucosa. Some studies have related secretor status with various diseases. Very few studies have been done in India, to relate IHD with ABO blood groups and secretor status. The present study was undertaken to determine, whether the correlation exists between IHD and ABO blood group and secretor status.

Two hundred IHD patients admitted in SJIC, Bangalore were studied for blood group and secretor status and compared with age and sex matched controls. Among the control group 'O' was most common while in the IHD patients, an overall excess of blood group 'A' was found. In the gender difference serum HDL values were significantly higher in females than males. Serum triglyceride values were significantly higher in blood group 'A' compared to other groups. IHD cases have been divided into MI and non MI group and its relation has been observed with blood group. There was significant excess of Myocardial infarction in blood group 'O' and 'B'.

In this study we have not observed any significant relation of IHD with secretor status.


Keywords

Ischemic Heart Disease, ABO Blood Group, Secretor Status
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  • ABO Blood Group and Secretor Status in IHD Patients

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Authors

Ashwini D. Pujari
Dept. of Physiology, MRMC, Gulbarga, India
Dinanath K. Pujari
Dept. of Anatomy, MRMC, Gulbarga, Karnataka, India

Abstract


Various studies have been done trying to relate ABO blood groups with diseases e.g. Peptic ulcer, duodenal ulcer, pernicious anaemia, gallstones, carcinoma of stomach and IHD. The same blood group antigens are secreted in the body fluids. The blood group antigens have protective action on its secreting mucosa. Some studies have related secretor status with various diseases. Very few studies have been done in India, to relate IHD with ABO blood groups and secretor status. The present study was undertaken to determine, whether the correlation exists between IHD and ABO blood group and secretor status.

Two hundred IHD patients admitted in SJIC, Bangalore were studied for blood group and secretor status and compared with age and sex matched controls. Among the control group 'O' was most common while in the IHD patients, an overall excess of blood group 'A' was found. In the gender difference serum HDL values were significantly higher in females than males. Serum triglyceride values were significantly higher in blood group 'A' compared to other groups. IHD cases have been divided into MI and non MI group and its relation has been observed with blood group. There was significant excess of Myocardial infarction in blood group 'O' and 'B'.

In this study we have not observed any significant relation of IHD with secretor status.


Keywords


Ischemic Heart Disease, ABO Blood Group, Secretor Status

References