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Posterior Reversible Encephalopathy Syndrome (PRES) following Disulfiram Intoxication - a Case Report


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1 Department of Radiodiagnosis, G.S.L. Medical College & Hospital, Rajahmundry, Andhra Pradesh
     

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Posterior reversible encephalopathy syndrome (PRES) also known as reversible posterior leukoencephalopathy (RPLS) is a syndrome characterized by headache, confusion, seizures and visual loss. It may occur due to a number of causes, predominantly malignant hypertension, ecclampsia and some medical treatments.

We present a case of PRES due to disulfiram intoxication in a chronic alcoholic patient. The condition was diagnosed on MRI which showed the typical radiological features. The patient recovered completely with complete reversal of radiological changes after the causative agent disulfiram was discontinued.


Keywords

Disulfiram, Reversible, Encephalopathy, MRI, White Matter
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  • Posterior Reversible Encephalopathy Syndrome (PRES) following Disulfiram Intoxication - a Case Report

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Authors

Anindita Mishra
Department of Radiodiagnosis, G.S.L. Medical College & Hospital, Rajahmundry, Andhra Pradesh
V Mythri Priyadarshi
Department of Radiodiagnosis, G.S.L. Medical College & Hospital, Rajahmundry, Andhra Pradesh

Abstract


Posterior reversible encephalopathy syndrome (PRES) also known as reversible posterior leukoencephalopathy (RPLS) is a syndrome characterized by headache, confusion, seizures and visual loss. It may occur due to a number of causes, predominantly malignant hypertension, ecclampsia and some medical treatments.

We present a case of PRES due to disulfiram intoxication in a chronic alcoholic patient. The condition was diagnosed on MRI which showed the typical radiological features. The patient recovered completely with complete reversal of radiological changes after the causative agent disulfiram was discontinued.


Keywords


Disulfiram, Reversible, Encephalopathy, MRI, White Matter

References