Open Access
Subscription Access
Open Access
Subscription Access
Seroprevalence of Hepatitis C Antibodies in Healthy Blood Donors in Western U.P, India
Subscribe/Renew Journal
Blood transfusion is an effective mode of transmission of hepatitis C infection. In developed countries various measures have been taken to reduce the spread of infection through this route. In India, mandatory screening for HCV was introduced as late as 2002 though it was started in Japan&US in 1990. Still, the studies all over India suggest that despite testing of blood units HCV infection is still a significant problem.
HCV is transmitted by blood to blood contact. In developing countries about 90 % of persons with chronic HCV were infected through transfusion of unscreened blood or blood products or via intravenous drug abuse or sexual exposure. Also, in developing countries, the primary sources of HCV infection may be unsterilized injection equipment.
The present study was conducted to find out seroprevalence of hepatitis C in 6000 donors in greater noida. The screening was done by ELISA third generation microelisa kit.
Seroprevalence of anti HCV in 6000 donors was 1.28 % with the prevalence of 1.34 % in voluntary&of 1.28% in replacement donors.
Males show higher incidence of 1.29%&females 0.66 %.
Blood group B negative showed higher positivity (1.886%) followed by A positive (1.408%) closely followed by O positive (1.4008%).
Age group >51 yrs show positivity of 5.405% followed by age group of 31-40 yrs ( 1.745 %)
Keywords
- Bassily S, Hyams KC, Fouad RA et al .A high risk of hepatitis C infection among Egyptian blood donors, role of parenteral abuse. Am J trop Med Hyg 1995;52(6);503-5.
- Gosavi MS, Shah SK, Shah SR et al .Prevalence of hepatitis C virus infection in Mumbai. Indian J med Sci 1997;51(10):378-85.
- Makroo RN, Raina V, Kaushik V. Prevalence of hepatitis C virus antibody in healthy blood donors. Indian J Med Res 1999 ;110:123-5.
- Sirchia G, Bellobuono A, Giovonetti A et al . Antibodies to hepatitis C virus in Italian blood donors, Lancet 1989:797.
- Mechave YV, Dhot PS. Prevalence of Hepatitis C virus antibody in heterogeneous population of blood donors. Med Jr. Armed forces India 1999;55:313-4.
- Per meet Kaur Bagga, SP Singh. Seroprevalence of hepatitis C antibodies in healthy blood donors –a prospective study. Ind J pathol and microbial 2007:vol 50(2);429-32.
Abstract Views: 221
PDF Views: 0