Indian Journal of Public Health Research & Development

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Primary Extraskeletal Ewing's Sarcoma of Nasal Cavity


Affiliations
1 Dept. of Pathology, Navodaya Medical College, Raichur, Karnataka
     

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Extra skeletal Ewing's Sarcoma (EES) of nasal cavity is a rare soft tissue tumor, morphologically similar to the commoner Ewing's sarcoma (ES) arising from bone. We report a case of EES of nasal cavity in a nine year old male who presented with nasal obstruction. Contrast enhanced CT scan showed mildly enhancing soft tissue attenuating mass. Histopathologically examination showed round cell tumor which was confirmed by special stain and immunohistochemistry. PAS showed positivity for intracellular glycogen, Immunohistochemistry showed positivity for MIC-2, CK, S- 100, EMA.

An extensive review of literature, to the best of our knowledge, did not reveal many cases of EES of nasal cavity, in children younger than ten years


Keywords

ES, Primitive Neuroectodermal Tumor ( PNET ), Nasal cavity, Children
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  • Tefft M, Vawter GF, Mitus A. Paravertebral ‘ Round cell ’ tumors in children. Radiology. 1969; 92: 1501-1509.

  • Angervall L, Enzinger FM. Extraskeletal neoplasm resembling Ewing’s sarcoma. Cancer. 1975; 36: 240-251.

  • Iriz A, Albayrak L, Eryilmaz A.Extraskeletal primary Ewing’s sarcoma of the nasal cavity. International journal of Paediatric Otorhinolaryngology 2007; 2(3):194-197.

  • Chaudary N, Gupta D, Natesh V, Singh S. Extra skeletal Ewing’s sarcoma of parapharyngeal space. International journal of pediatric otorhinolaryngology 2010; 5 (4): 159-164.

  • Ewing J. Diffuse endothelioma of bone. Proc NY Pathol Soc. 1921; 21:17–24.

  • Harman M, Kiroglu F, Kosen M, Unal O. Primary Ewing’s sarcoma of the paranasal sinus with intracranial extension; Imaging features. Dentomaxillofacial radiology. 2003; 32: 343-346.

  • Kang MS, Yoon HK, Choi JB, Eum JW. Extraskeletal Ewing’s sarcoma of the hard palate. J Korean Med Sci 2005; 20: 687- 690.

  • Boor A, Jurkovic I, Friedmann I, Plank L, Kocan P. Extraskeletal Ewing’s sarcoma of the nose. J. Laryngol. Otol. 2001; 115: 74-76.

  • Lane S, Ironside JW. Extra skeletal ewings sarcoma of the nasal fossa. J. Laryngol. Otol. 1990; 104: 570-573.

  • Howard DJ, Daniels HA. Ewings sarcoma of the nose. Ear Nose Throat J. 1993; 72: 277-279.

  • Howarth KL, Khodaei I, Karkanevatos A, Clarke RW. A sinonasal primary Ewing’s sarcoma. Int. J. Pediatr. Otorhinolaryngol. 2004; 68:221–224.

  • Aferzon M, Wood WE, Powell JR. Ewing’s sarcoma of the ethmoid sinus. Otolaryngol. Head Neck Surg. 2003; 128:897–901.

  • Guiter GE, Gamboni MM, Zakowski MF. The cytology of extraskeletal Ewing sarcoma. Cancer. 1999;87:141–148.

  • Csokonai LV, Liktor B, Arato G, Helffrich F. Ewings sarcoma in the nasal cavity. Otolaryngol. Head Neck Surg. 2001;125:665-667.

  • Sandoval C, Meyer WH, Parham DM, Kun LE, Hustu HO, Luo X, et al. Outcome in 43 children presenting with metastatic Ewing’s Sarcoma: The St. Jude Childrens research hospital experience, 1962-1992.Med. Pediatr. Oncol.1996; 26:180-185.

  • Toda T, Atari E, Sadi AM, Kiyuna M, Kojya S. Primitive neuroectodermal tumor in sinonasal region. Auris Nasus Larynx. 1999; 26:83-90.


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  • Primary Extraskeletal Ewing's Sarcoma of Nasal Cavity

Abstract Views: 391  |  PDF Views: 0

Authors

A S Anand
Dept. of Pathology, Navodaya Medical College, Raichur, Karnataka
V R Chandrakanth
Dept. of Pathology, Navodaya Medical College, Raichur, Karnataka
C M Sagar
Dept. of Pathology, Navodaya Medical College, Raichur, Karnataka
Vidisha Athanikar
Dept. of Pathology, Navodaya Medical College, Raichur, Karnataka

Abstract


Extra skeletal Ewing's Sarcoma (EES) of nasal cavity is a rare soft tissue tumor, morphologically similar to the commoner Ewing's sarcoma (ES) arising from bone. We report a case of EES of nasal cavity in a nine year old male who presented with nasal obstruction. Contrast enhanced CT scan showed mildly enhancing soft tissue attenuating mass. Histopathologically examination showed round cell tumor which was confirmed by special stain and immunohistochemistry. PAS showed positivity for intracellular glycogen, Immunohistochemistry showed positivity for MIC-2, CK, S- 100, EMA.

An extensive review of literature, to the best of our knowledge, did not reveal many cases of EES of nasal cavity, in children younger than ten years


Keywords


ES, Primitive Neuroectodermal Tumor ( PNET ), Nasal cavity, Children

References