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Association of Serum Levels of Vitamin D and Interleukin 6 in Type 1 Diabetes in an Egyptian Population


Affiliations
1 Professor of Clinical Pathology, Faculty of Medicine, Minia University, Minia, Egypt
2 Assistant Professor of Clinical Pathology, Faculty of Medicine, Minia University, Minia, Egypt
     

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Type 1 diabetes is an inflammatory disease of the pancreatic is lets due interaction of activated T-cells and proinflammatory cytokines in the immune infiltrate. Vitamin D has vital immunomodulatory properties that help in prevention of occurrence of T1DM.IL-6 is a multifunctional cytokine which has role in the pathogeneses of type 1 diabetes. This study was conducted to evaluate levels of vitamin D and IL6 in type 1 diabetic children and their relation to RBS, glycemic control and c-peptide level.

Keywords

Type I diabetes, vitamin D, Il-6, immunomodulatory process
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  • Association of Serum Levels of Vitamin D and Interleukin 6 in Type 1 Diabetes in an Egyptian Population

Abstract Views: 80  |  PDF Views: 0

Authors

Ashraf M. Osman
Professor of Clinical Pathology, Faculty of Medicine, Minia University, Minia, Egypt
Hanan M. Kamel
Professor of Clinical Pathology, Faculty of Medicine, Minia University, Minia, Egypt
Lamia H. Ali
Professor of Clinical Pathology, Faculty of Medicine, Minia University, Minia, Egypt
Hend M. Moness
Professor of Clinical Pathology, Faculty of Medicine, Minia University, Minia, Egypt
Dalia A. Meshref
Assistant Professor of Clinical Pathology, Faculty of Medicine, Minia University, Minia, Egypt

Abstract


Type 1 diabetes is an inflammatory disease of the pancreatic is lets due interaction of activated T-cells and proinflammatory cytokines in the immune infiltrate. Vitamin D has vital immunomodulatory properties that help in prevention of occurrence of T1DM.IL-6 is a multifunctional cytokine which has role in the pathogeneses of type 1 diabetes. This study was conducted to evaluate levels of vitamin D and IL6 in type 1 diabetic children and their relation to RBS, glycemic control and c-peptide level.

Keywords


Type I diabetes, vitamin D, Il-6, immunomodulatory process



DOI: https://doi.org/10.37506/v11%2Fi2%2F2020%2Fijphrd%2F194980