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The Effect of Metabolic Syndrome on Systolic Function of Left Ventricle Using Echocardiographic Examination


Affiliations
1 Clinical Pharmacy Department-Faculty of Pharmacy-Misr University for Science and Technology, Egypt
2 Pharmaceutical Department-Faculty of Pharmacy-Menia University, Egypt
3 Internal Medicine Department- Faculty of Medicine-Misr University for Science and Technology, Egypt
4 Cardiology Department Faculty of Medicine-Misr University for Science and Technology, Egypt
     

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Objective: Metabolic syndrome may cause bad prognosis on diastolic or systolic function of the left ventricle. Thus, this research aimed to recognize the possible effect of metabolic syndrome on systolic and diastolic function of left ventricle using ECHO. Study Design: Prospective case-control study. Place and duration of study: Soad Kafafi Hospital, Egypt, from May 2016 to March 2018. Methodology: This research included forty patients with metabolic syndrome (18 male, 22 female, mean age=54.13±6.33 years) and forty control matching age and sex volunteers without history of metabolic syndrome disorder (15 male, 25 female, mean age=52.20±5.27).MS was defined according to ATP-NCEP III criteria. Waist circumference will be measured to all participants at the start of study inclusion. Height and weight was measured to calculate Body mass index using standardized formula. Participants underwent laboratory investigations and complete echocardiography. Left ventricular function of the heart was assessed using Echocardiographic examination. Results: There was a statistical significant difference regarding Left atrial (LA) diameter, Inter ventricular septum and posterior wall thickness in metabolic syndrome patients than normal control persons. The incidence of diastolic dysfunction was significantly higher in metabolic syndrome group compared to control. Conclusion: MS may cause LV diastolic dysfunction although systolic function was preserved.

Keywords

metabolic syndrome, diastolic dysfunction, diabetes, hypertension, left ventricular function
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  • The Effect of Metabolic Syndrome on Systolic Function of Left Ventricle Using Echocardiographic Examination

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Authors

Doaa H. EL-Farook
Clinical Pharmacy Department-Faculty of Pharmacy-Misr University for Science and Technology, Egypt
Hatem A. Sarhan
Pharmaceutical Department-Faculty of Pharmacy-Menia University, Egypt
Manal M. Mohamed
Internal Medicine Department- Faculty of Medicine-Misr University for Science and Technology, Egypt
Ahmed EL-Barbary
Cardiology Department Faculty of Medicine-Misr University for Science and Technology, Egypt
Khaled A. Khaled
Pharmaceutical Department-Faculty of Pharmacy-Menia University, Egypt

Abstract


Objective: Metabolic syndrome may cause bad prognosis on diastolic or systolic function of the left ventricle. Thus, this research aimed to recognize the possible effect of metabolic syndrome on systolic and diastolic function of left ventricle using ECHO. Study Design: Prospective case-control study. Place and duration of study: Soad Kafafi Hospital, Egypt, from May 2016 to March 2018. Methodology: This research included forty patients with metabolic syndrome (18 male, 22 female, mean age=54.13±6.33 years) and forty control matching age and sex volunteers without history of metabolic syndrome disorder (15 male, 25 female, mean age=52.20±5.27).MS was defined according to ATP-NCEP III criteria. Waist circumference will be measured to all participants at the start of study inclusion. Height and weight was measured to calculate Body mass index using standardized formula. Participants underwent laboratory investigations and complete echocardiography. Left ventricular function of the heart was assessed using Echocardiographic examination. Results: There was a statistical significant difference regarding Left atrial (LA) diameter, Inter ventricular septum and posterior wall thickness in metabolic syndrome patients than normal control persons. The incidence of diastolic dysfunction was significantly higher in metabolic syndrome group compared to control. Conclusion: MS may cause LV diastolic dysfunction although systolic function was preserved.

Keywords


metabolic syndrome, diastolic dysfunction, diabetes, hypertension, left ventricular function



DOI: https://doi.org/10.37506/v11%2Fi2%2F2020%2Fijphrd%2F194972