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How Efficacious is Esmolol in Suppressing the Stress Response to Laryngoscopy and Intubation in ENT Surgeries


Affiliations
1 Associate Professor, Department of Anaesthesia, MMIMSR, Mullana, Ambala, India
2 Assistant Professor, Department of E.N.T.GMC, Patiala,, India
3 ENT Consultant, Department of Anaesthesia, MMIMSR, Mullana, Ambala, India
4 Post Graduate Student, MMIMSR, Mullana, Ambala, India
     

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Introduction: Attenuation of stress response during laryngoscopy and intubation has been one of the major concerns of the anaesthetist. Various techniques have been used to suppress this response like deepening the level of anaesthesia and various drugs like β blockers,local anaestheticsetc. In this study Esmolol was used to suppress the stress response. Material and Method: 60 patients undergoing elective ENT surgery under general anaesthesia of ASA grade I and II were randomly divided into two groups of 30 each. Group I (n=30)-Control –no drug was given. Group II (n=30)-patients received pretreatment with Injection Esmolol 0.5mg/kg. Results: The results were tabulated and statistically analyzed with student t-test and Chi square test using ANOVA (analysis of variance). Conclusion: Esmolol attenuates the stress response to laryngoscopy and intubation in the form of increase in pulse rate and blood pressure and that esmolol given 3 minutes before induction provides stable cardiovascular conditions as compared to the control group and attenutates the pressor response but does not obliterate it completely.

Keywords

Esmolol, Stress Response, Laryngoscopy, Intubation.
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  • How Efficacious is Esmolol in Suppressing the Stress Response to Laryngoscopy and Intubation in ENT Surgeries

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Authors

Babita Ramdev
Associate Professor, Department of Anaesthesia, MMIMSR, Mullana, Ambala, India
Dinesh Kumar Sharma Sharma
Assistant Professor, Department of E.N.T.GMC, Patiala,, India
Sangita R. Sharma
ENT Consultant, Department of Anaesthesia, MMIMSR, Mullana, Ambala, India
Sapna Bansal
Associate Professor, Department of Anaesthesia, MMIMSR, Mullana, Ambala, India
T. Venugopal
Post Graduate Student, MMIMSR, Mullana, Ambala, India
Ritu Singh
Post Graduate Student, MMIMSR, Mullana, Ambala, India

Abstract


Introduction: Attenuation of stress response during laryngoscopy and intubation has been one of the major concerns of the anaesthetist. Various techniques have been used to suppress this response like deepening the level of anaesthesia and various drugs like β blockers,local anaestheticsetc. In this study Esmolol was used to suppress the stress response. Material and Method: 60 patients undergoing elective ENT surgery under general anaesthesia of ASA grade I and II were randomly divided into two groups of 30 each. Group I (n=30)-Control –no drug was given. Group II (n=30)-patients received pretreatment with Injection Esmolol 0.5mg/kg. Results: The results were tabulated and statistically analyzed with student t-test and Chi square test using ANOVA (analysis of variance). Conclusion: Esmolol attenuates the stress response to laryngoscopy and intubation in the form of increase in pulse rate and blood pressure and that esmolol given 3 minutes before induction provides stable cardiovascular conditions as compared to the control group and attenutates the pressor response but does not obliterate it completely.

Keywords


Esmolol, Stress Response, Laryngoscopy, Intubation.



DOI: https://doi.org/10.37506/v11%2Fi2%2F2020%2Fijphrd%2F194939