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Treatment Success Rate among Multi-Drug Resistant Tuberculosis Patients Registered Under Programmatic Management of Drug Resistant Tuberculosis Services in District Amritsar, Punjab, India


Affiliations
1 Associate Professor, Department of Community Medicine, Sri Guru Ram Das Institute of Medical Sciences and Research, Sri Amritsar, India
2 District TB Officer, Office of Civil Surgeon, Tarn Taran, Punjab, India
3 Professor & Head, Department of Community Medicine, Sri Guru Ram Das Institute of Medical Sciences and Research, Sri Amritsar, India
     

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Background: MDR-TB has become an urgent public health problem worldwide, threatening the global TB control. The success rate of treating multi drug resistant remains very low.

Method: This cross-sectional study was conducted on all MDR-TB patients who were registered and being treated under PMDT services in Amritsar district from 1st January 2015 to 31st December 2016. The treatment outcome with their clinico-demographic determinants was ascertained. Data management and analysis was done by using Microsoft excel and SPSS.

Results: Out of 110 registered MDR-TB patients, 88 (80.0%) were males and 22 (20.0%) were females. The various treatment outcomes observed were- 36 (32.7%) cured, 20 (18.2%) treatment completed, 16 (14.5%) defaulted, 22 (20.0%) died, 11 (10.0%) regimen changed or shifted to XDR TB regime, 5(4.5%) transferred out. The success rate (cured + treatment completed) was 50.9%.

Conclusions: On statistical analysis, it was observed that age (p=0.012), weight band of patients under RNTCP (p=0.040) were significantly associated with the treatment outcome. Other factors like sex, residence, type of tuberculosis and the HIV status of the patient did not affect the treatment outcome.


Keywords

Multi-Drug Resistant TB, Treatment Outcomes, Success Rate.
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  • Treatment Success Rate among Multi-Drug Resistant Tuberculosis Patients Registered Under Programmatic Management of Drug Resistant Tuberculosis Services in District Amritsar, Punjab, India

Abstract Views: 37  |  PDF Views: 0

Authors

Pooja Sadana
Associate Professor, Department of Community Medicine, Sri Guru Ram Das Institute of Medical Sciences and Research, Sri Amritsar, India
Vishal Verma
District TB Officer, Office of Civil Surgeon, Tarn Taran, Punjab, India
Priyanka Devgun
Professor & Head, Department of Community Medicine, Sri Guru Ram Das Institute of Medical Sciences and Research, Sri Amritsar, India

Abstract


Background: MDR-TB has become an urgent public health problem worldwide, threatening the global TB control. The success rate of treating multi drug resistant remains very low.

Method: This cross-sectional study was conducted on all MDR-TB patients who were registered and being treated under PMDT services in Amritsar district from 1st January 2015 to 31st December 2016. The treatment outcome with their clinico-demographic determinants was ascertained. Data management and analysis was done by using Microsoft excel and SPSS.

Results: Out of 110 registered MDR-TB patients, 88 (80.0%) were males and 22 (20.0%) were females. The various treatment outcomes observed were- 36 (32.7%) cured, 20 (18.2%) treatment completed, 16 (14.5%) defaulted, 22 (20.0%) died, 11 (10.0%) regimen changed or shifted to XDR TB regime, 5(4.5%) transferred out. The success rate (cured + treatment completed) was 50.9%.

Conclusions: On statistical analysis, it was observed that age (p=0.012), weight band of patients under RNTCP (p=0.040) were significantly associated with the treatment outcome. Other factors like sex, residence, type of tuberculosis and the HIV status of the patient did not affect the treatment outcome.


Keywords


Multi-Drug Resistant TB, Treatment Outcomes, Success Rate.



DOI: https://doi.org/10.37506/v11%2Fi1%2F2020%2Fijphrd%2F193857