Differences in Consumption of Flavonoid Phytochemicals toward Total Cholesterol and LDL-Cholesterol Levels in Dyslipidemia and Non-Dyslipidemia Groups of Minangkabau Ethnic Women

Introduction: Dyslipidemia is the primary risk factor for cardiovascular disease. Prevalance of dyslipidemia in Indonesia is still high, which is related to lifestyles such as unhealthy diet. Flovonoids are one type of phytochemical that is abundant in fruits, vegetables, nuts, and flavors that have a preventive effect on degenerative diseases.

Purpose: To determine differences in flavonoid phytochemical consumption of total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C) in dyslipidemia and non-dyslipidemia groups of Minangkabau ethnic women.

Method: The study design was comparative cross-sectional, examination of lipid levels of TC and LDL-C was carried out to determine dyslipidemia status. Subjects consisted of 72 women with dyslipidemia and 74 women with non-dyslipidemia. Interviews on food consumption used a food consumption frequency questionnaire (semi-quantitative food frequency questionnaire).

Results: The mean TC and LDL-C were higher in the dyslipidemia group, there was an inverse correlation between flavan 3-ols, flavones, flavonols, antocyanidins and isoflavones with TC and LDL-C. There were significant differences in flavonols and antocyanidin consumptions among the dyslipidemia and nondyslipidemia groups (p < 0.05).

Conclusion: The flavonoid consumption can improve dyslipidemia status (TC and LDL-C).