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Feasibility of Quantitative Diffusion Weighted MR Imaging with Calculated Apparent Diffusion Coefficients in Characterization of Pediatric Head and Neck Masses


Affiliations
1 National Cancer Institute, Cairo University, Egypt
2 Radiology Department, University of Missouri, National Cancer Institute, Cairo University, Egypt
3 Cairo University, Egypt
     

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Purpose: Assessing DW MR imaging and ADC value in pediatric head and neck lesions and ability of determination benign from malignant masses.

Methods: Study was undertaken on 56 patients as 39:17, male: female, respectively where they had head or neck mass. Patients exposed to routine MRI to characterize lesions. Diffusion weighted imaging sequence was added to routine MR and evaluation of DWIs.

Results: We found that ± ADC of malignant, benign lesions as0.64 X 10-3, 1.58 X 10-3, and 2.10 X 10-3 mm2/sec. ADC of 1.25 X 10-3 mm2/sec threshold value was used to differentiating among tumors which were represented 100% and 94.1% for sensitivity and specificity, respectively.

Conclusion: Beneficial roles for DW imaging to discriminate between malignant and benign head and neck tumors.


Keywords

Diffusion MR Imaging, Pediatric Head and Neck Masses.
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  • Feasibility of Quantitative Diffusion Weighted MR Imaging with Calculated Apparent Diffusion Coefficients in Characterization of Pediatric Head and Neck Masses

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Authors

Ahmed Gabr
National Cancer Institute, Cairo University, Egypt
Ayman M. Nada
Radiology Department, University of Missouri, National Cancer Institute, Cairo University, Egypt
Mohammed Gomaa
National Cancer Institute, Cairo University, Egypt
Rania Hashem
Cairo University, Egypt
Ahmed Shokry
National Cancer Institute, Cairo University, Egypt
Ahmad Kamel
National Cancer Institute, Cairo University, Egypt

Abstract


Purpose: Assessing DW MR imaging and ADC value in pediatric head and neck lesions and ability of determination benign from malignant masses.

Methods: Study was undertaken on 56 patients as 39:17, male: female, respectively where they had head or neck mass. Patients exposed to routine MRI to characterize lesions. Diffusion weighted imaging sequence was added to routine MR and evaluation of DWIs.

Results: We found that ± ADC of malignant, benign lesions as0.64 X 10-3, 1.58 X 10-3, and 2.10 X 10-3 mm2/sec. ADC of 1.25 X 10-3 mm2/sec threshold value was used to differentiating among tumors which were represented 100% and 94.1% for sensitivity and specificity, respectively.

Conclusion: Beneficial roles for DW imaging to discriminate between malignant and benign head and neck tumors.


Keywords


Diffusion MR Imaging, Pediatric Head and Neck Masses.



DOI: https://doi.org/10.37506/v10%2Fi12%2F2019%2Fijphrd%2F192433