Porphyromonas Gingivalis fimA Genotype in Chronic Periodontitis

Background: Periodontitisis an inflammation of the periodontium with varied etiologyleading to loss of periodontal supporting tissues of the teeth including the periodontal ligament and alveolar bone. Periodontitis progresses as a result of the direct effects of bacterial virulence factors on host tissues, as well as selfdamaging host responses to the colonizing bacteria.

Method: PCR was performed on the sub gingival plaque samples positive for P.gingivalis from chronic periodontitis patients (n=103) and healthy subjects (n=22) Chi-square test was performed to calculate the statistical significance.

Result: P.gingivalis type II fimA genotype was positivein 50.5% and 13.60% among patients with chronic periodontitis and health respectively. positivity for P.gingivalistype II fimA genotype. Statistical significance was observed for the prevalence of P.gingivalistype II fimA genotype (p=0.03) in chronic periodontitis group.

Conclusion: The significant presence of P. gingivalistype II fimA genotypein chronic periodontitis compared to health suggests their role in the etiology of chronic periodontitis.