Comparative Evaluation of Effect of Preoperative Oral Medication of Ketorolac on Anesthetic Efficacy of Inferior Alveolar Nerve Block in Patients with Irreversible Pulpitis:A Randomized Clinical Trial

Aim: The purpose of this randomized control study was to determine the effect of the administration of the preoperative ketorolac on the success of the inferior alveolar nerve (IAN) block in patients with symptomatic irreversible pulpitis

Materials and Method: Ninety adult volunteers who were actively experiencing pain participated in this study. The subjects were divided into 3 groups on a random basis and were randomly divided into three groups. Group 1 patients were advised to take tablet Ketorol-DT for 2 days as per the dosage recommendation by the manufacturer before the endodontic procedure. Group 2 patients were given tablet Ketorol-DT 1 hour before anesthesia and group 3 patients receive no preoperative medication. All patients received standard inferior alveolar nerve block of 2% lidocaine with 1:80,000 epinephrine. Endodontic access preparation was initiated after 15 minutes of initial inferior alveolar nerve block. Pain during treatment was recorded by using Heft Parker visual analog scale. Success was recorded as none or mild pain.

Result: Preoperative administration of tablet Ketorol-DT before 2days has a significant effect on success rate of Inferior alveolar nerve block in patients with irreversible pulpitis. There is no statistical difference between group 2 and group 3.

Conclusion: Preoperative administration of tablet Ketorol-DT before 2days has a significant effect on success rate of Inferior alveolar nerve block in patients with Irreversible pulpitis.