Protocol for Review of “Efficiency of Probiotics”

Introduction: According to World Health Organization, “Gestational Diabetes Mellitus (GDM) is defined as any degree of glucose intolerance with onset or first recognized during pregnancy”. The goal of this review is to determine the efficiency of probiotics on maternal blood glucose level among patients with gestational diabetes mellitus and to analyse its effects on glycaemic control.

Method: This review will include only randomized controlled trials that are in English, published between the year 2008 to 2018. The data will be collected from the following electronic databases: namely Google Scholar, Pubmed and Cochrane. Data will be collected using some of the following medical subheading (MeSH) terms as search string:#probiotics (mesh terms)#, #probiotics# [All Fields] OR #Lactobacillus# OR #Bifidibacterium#, #Glycaemic control#, #Effects#, # gestational diabetes mellitus#, #fasting blood glucose level#, #insulin level#.

Discussion: The studies identified will be reviewed and assessed for its relevancy and quality based on the Joanna Briggs Institute (JBI) guidelines by two independent reviewers. JBI data extraction form for experimental studies from JBI Reviewer’s Manual will be used to extract the quantitative data from the included studies. Narrative analysis, qualitative synthesis and meta-analysis will be used to report the findings of the review.