Correlative Study of Prolactin Level and Hypothyroidism in Both Primary and Secondary Infertility in Females of Uttar Pradesh

In the present study, 40 females of primary infertility and 40 females of secondary infertility aged between 18-40 years were studied, primary infertility females grouped as group-A and secondary infertility females grouped as group-B. In group A,the duration of marriage of 21 (52.5%) was 1 to 5 years, 12 (30%) had 6 to 10 years, 7(17.5%) had more than 10 years. In group B, 11(27.5%) had 1-5 years of marriage duration, 16(40%) had 6-10 years and 13(32.5%) had more than 10 years of marriage period. The menses history in group A was: 13(32.5%) had regular menses, 19(47.5%) had oligomenorrhea, 5(12.5%) had amenorrhea and 3(7.5%) had menorrhagia. In group B, 12(30%) had regular menses, 17(45.5%) had oligomenorrhea, 9(421.5%) hadoligomenorrhea, 9(22.5%) had amenorrhea and 2(5%) had menorrhagia.In group A, serum prolactin level in 17(42.5%) females was 0-20mg/ml, 23 (57.5%) was 21-100mg/ml. In group B, 26(65%) had 21- 100mg/ml and1(2.5%) had >100 mg/ml. In group A, TSH level in 3(7.5%) was 4.7 μIU/ml. In group B 2(5%) females had 4.7 μIU/ml. This correlative study of S. prolactin and TSH hormones will be quite useful to obstetrics and gynecologist, endocrinologist, to rule out proper cause and treat the infertility efficiently, because due to increased rate of infertility majority of couples are finding surrogative mothers which are quite expensive and may lead to legal complications.