Indian Journal of Forensic Medicine & Toxicology

Zinah Salah Mawlood ¹, Ghassan Abdul-Hamid Naji ¹

Affiliations
1 Department of Prosthodontics, College of Dentistry/ University of Baghdad, IQ

Abstract

The aim of the current study is to evaluate the antifungal efficacy of several different percentages of Bergamot Essential Oil (BEO) incorporated into heat cure PMMA denture base material against Candida albicans.

Materials and Method: Eighty samples were divided into eight groups including six various percentages of BEO (2%,3%, 4% ,5%, 6% and 7% by volume) and 0% BEO as a control group, in addition to 1.4% by weight of nystatin which represent the positive control group. All these additives were incorporated into heat cure PMMA denture material. After 48h incubation in distilled water, all samples were assessed by Candida albicans colonies viable count test.

Results: For Candida albicans activity test; the experimental groups (2%,3%, 4%, 5%, 6% and 7% of BEO) showed highly significant decrease in the mean values of the viable count of Candida albicans when compared to the control group (0% BEO) (p<0.01). In contrast, a non-significant difference among experimental groups and 1.4% nystatin group.

Conclusion: Bergamot essential oil was successfully incorporated into heat cure PMMA denture base material and could act as potential antifungal agent with a drug delivery system against Candida albicans. It seemed that adding of 5% and 6% BEO was the most beneficial effects against the growth of fungi. 

Keywords

Heat Cure PMMA, Denture Base, Bergamot Essential Oil, Nystatin, Candida Albicans.

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Ghassan Abdul-Hamid Naji ¹, Mohammed Moudhaffer Ali ¹, Firas Abdulameer Farhan ¹

Affiliations
1 Department of Prosthodontics, College of Dentistry/ University of Baghdad, IQ

Abstract

The aim of this study was to assess the effect of glass flakes addition on some physical and mechanical properties of a maxillofacial silicone material. Material and method: A room temperature vulcanized (RTV) maxillofacial silicone (VST-50, Factor II Inc., USA) and Micronized glass flake, surface pre-treated with silane coupling agent (GF002, Glass flake Ltd, Leeds, UK) were used in this study. Two hundred (200) specimens were prepared and divided into five main groups based on the tests conducted (tear strength, tensile strength, elongation percentage, surface hardness and surface roughness). Then, each group was farther divided into four subgroups according to weight percentage of glass flakes as follow; control group (0%), other groups contain 0.5%, 1% and 1.5% of glass flake micro-particles (10 specimen from each group). Results: The collected data were analyzed with a one-way ANOVA and LSD multiple comparison test were utilized to show the differences among four studied groups. The 1% glass flakes-incorporated specimens exhibited the highest mean values of tear strength, tensile strength and elongation percentage. While, the highest mean values of hardness and roughness were obtained with 1.5% specimens.

Keywords

Glass flakes, Maxillofacial silicone material (VST-50), Tear strength, Tensile strength, elongation percentage, Hardness, Roughness.

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