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Risk of Hemorrhage in Methanol Toxicity


Affiliations
1 Loghman-Hakim Poison Hospital, Department of Clinical Toxicology and Forensic Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran, Islamic Republic of
2 Toxicological Research Center,Shahid Beheshti University of Medical Sciences, Tehran, Iran, Islamic Republic of
3 Department of Clinical Toxicology and Forensic Medicine, Iran University of medical sciences, Tehran, Iran, Islamic Republic of
     

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Methanol is a clear, colorless liquid with a smell and taste similar to ethanol. Intoxications with methanol are still frequent in large parts of the developing world. Hemodialysis should be done in severe toxicity to eliminate toxic metabolites. In this case report, we describe 37-year-old chronic alcohol abuser with methanol poisoning, who got hematuria and upper GI bleeding after hemodialysis. The upper GI endoscopic findings showed only low grade esophageal ulcer. Hematuria and upper GI bleeding in our patient might also have been due to the effect of heparinization during hemodialysis.
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  • Rathi M, Sakhuja V, Jha V. Visual blurring and metabolic acidosis after ingestion of bootlegged alcohol. Hemodial Int. 2006 Jan; 10(1):8-14.
  • Blanco M, Casad R, zquez F. Va´, Pumar J. M. CT and MR Imaging Findings in Methanol Intoxication. AJNR Am J Neuroradiol. 2006 Feb;27:452– 454
  • Jacobsen D, McMartin K. Methanol and formaldehyde poisoning. In: Brent J, Wallace K.L, Burkhat K.K, Phillips S.D, Donovan J .W. Critical Care Toxicology. 1st ed. Elsevier Mosby.2005; 42:475-484
  • Kraut JA, Kurtz I. Toxic alcohol ingestions: clinical features, diagnosis, and management. Clin J Am Soc Nephrol. 2008 Jan; 3(1):208-25.
  • Seth Schonwald, MD, et al, Medical Toxicology: a synopsis and study guide, Alcohols, second edition, USA: lippincott Williams & wilkins, 2001.p 164: 22-26.
  • Lewis R.Goldfranks, MD, et al, Toxicologic Emergencies : Toxic Alcohols, 7th Edition, USA : McGraw – Hill, 2002 . p 982: 25-30.
  • Théfenne H, Turc J, Carmoi T, Gardet V, Renard C.[Acute methanol poisoning: about. 2005 Sep-Oct;63(5):556-60. one case]
  • Kalkan S, Cevik AA, Cavdar C, Aygoren O, Akgun A, Ergun N, Tuncok Y Acute methanol poisonings reported to the Drug and Poison Information Center in Izmir, Turkey. Vet Hum Toxicol. 2003 Dec; 45(6):334-7.
  • Sebe A, Satar S, Uzun B, Topal M, Yesilagac H, Avci A. Intracranial hemorrhage associated with methanol intoxication. Mt Sinai J Med. 2006 Dec; 73(8):1120-2.
  • Giudicissi FM, Holanda CV, Nader NA, et al. Bilateral putaminal hemorrhage related to methanol poisoning: a complication of hemodialysis? Case report. Arq Neuropsiquiatr 1995; 53(3-A):485–487.
  • xPhang PT, Passerini L, Mielke B, et al. Brain hemorrhage associated with methanol poisoning. Crit Care Med 1988; 16(2):137–140

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  • Risk of Hemorrhage in Methanol Toxicity

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Authors

Babak Mostafazadeh
Loghman-Hakim Poison Hospital, Department of Clinical Toxicology and Forensic Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran, Islamic Republic of
Arezou Mahdavinejad
Toxicological Research Center,Shahid Beheshti University of Medical Sciences, Tehran, Iran, Islamic Republic of
Abbas Aghabiklooei
Department of Clinical Toxicology and Forensic Medicine, Iran University of medical sciences, Tehran, Iran, Islamic Republic of

Abstract


Methanol is a clear, colorless liquid with a smell and taste similar to ethanol. Intoxications with methanol are still frequent in large parts of the developing world. Hemodialysis should be done in severe toxicity to eliminate toxic metabolites. In this case report, we describe 37-year-old chronic alcohol abuser with methanol poisoning, who got hematuria and upper GI bleeding after hemodialysis. The upper GI endoscopic findings showed only low grade esophageal ulcer. Hematuria and upper GI bleeding in our patient might also have been due to the effect of heparinization during hemodialysis.

References